| 1 |
31868102 | Ellagitannins from Punica granatum leaves suppress microsomal prostaglandin E synthase-1 expression and induce lung cancer cells to undergo apoptosis. | 2020 Apr |
1 |
| 2 |
32410351 | Polysubstituted Pyrimidines as mPGES-1 Inhibitors: Discovery of Potent Inhibitors of PGE2 Production with Strong Anti-inflammatory Effects in Carrageenan-Induced Rat Paw Edema. | 2020 Aug 5 |
2 |
| 3 |
32655834 | miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells. | 2020 Jun 30 |
1 |
| 4 |
27012893 | Insights into the structure activity relationship of mPGES-1 inhibitors: Hints for better inhibitor design. | 2016 Jul |
1 |
| 5 |
27177970 | Identification of the two-phase mechanism of arachidonic acid regulating inflammatory prostaglandin E2 biosynthesis by targeting COX-2 and mPGES-1. | 2016 Aug 1 |
2 |
| 6 |
27482714 | The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation. | 2016 Aug |
1 |
| 7 |
27597418 | Inhibition of the enzymes in the leukotriene and prostaglandin pathways in inflammation by 3-aryl isocoumarins. | 2016 Nov 29 |
1 |
| 8 |
25260492 | Development of 2-aryl substituted quinazolin-4(3H)-one, pyrido[4,3-d]pyrimidin-4(3H)-one and pyrido[2,3-d]pyrimidin-4(3H)-one derivatives as microsomal prostaglandin E(2) synthase-1 inhibitors. | 2014 Oct 15 |
1 |
| 9 |
23260349 | Discovery and SAR of PF-4693627, a potent, selective and orally bioavailable mPGES-1 inhibitor for the potential treatment of inflammation. | 2013 Feb 15 |
1 |
| 10 |
24101387 | The effect of reactive oxygen species on the synthesis of prostanoids from arachidonic acid. | 2013 Aug |
1 |
| 11 |
22337655 | Lead discovery for microsomal prostaglandin E synthase using a combination of high-throughput fluorescent-based assays and RapidFire mass spectrometry. | 2012 Jun |
1 |
| 12 |
22449023 | Structure-activity relationship of nonacidic quinazolinone inhibitors of human microsomal prostaglandin synthase 1 (mPGES 1). | 2012 Apr 26 |
1 |
| 13 |
22822059 | Cyclooxygenase-2, not microsomal prostaglandin E synthase-1, is the mechanism for interleukin-1β-induced prostaglandin E2 production and inhibition of insulin secretion in pancreatic islets. | 2012 Sep 14 |
1 |
| 14 |
20844471 | Amelioration of cisplatin nephrotoxicity by genetic or pharmacologic blockade of prostaglandin synthesis. | 2011 Jan |
2 |
| 15 |
21310608 | A novel class of dual mPGES-1/5-LO inhibitors based on the α-naphthyl pirinixic acid scaffold. | 2011 Mar 1 |
1 |
| 16 |
21410457 | A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm. | 2011 Aug |
2 |
| 17 |
21576350 | Selective PGE(2) suppression inhibits colon carcinogenesis and modifies local mucosal immunity. | 2011 Aug |
1 |
| 18 |
20546888 | Coordinated up-regulation of cyclooxygenase-2 and microsomal prostaglandin E synthase 1 transcription by nuclear factor kappa B and early growth response-1 in macrophages. | 2010 Oct |
1 |
| 19 |
18984580 | Mutation of a critical arginine in microsomal prostaglandin E synthase-1 shifts the isomerase activity to a reductase activity that converts prostaglandin H2 into prostaglandin F2alpha. | 2009 Jan 2 |
1 |
| 20 |
19114118 | Up-regulation of microsomal prostaglandin E synthase-1 in COX-1 and COX-2 knock-out mouse fibroblast cell lines. | 2009 Apr |
1 |
| 21 |
18240928 | Induction of prostaglandin E2 synthesis and microsomal prostaglandin E synthase-1 expression in murine microglia by glioma-derived soluble factors. Laboratory investigation. | 2008 Feb |
1 |
| 22 |
17437488 | The expression pattern of prostaglandin E synthase and EP receptor isoforms in normal mouse skin and preinvasive skin neoplasms. | 2007 May |
2 |
| 23 |
16619662 | Induction of macrophagic prostaglandin E2 synthesis by glioma cells. | 2006 Apr |
1 |
| 24 |
16720448 | Simultaneous expression of cyclooxygenase-2 and microsomal prostaglandin E synthase in squamous cell carcinoma of the larynx. | 2006 Jun |
1 |
| 25 |
16766159 | Signal pathways involved in the regulation of prostaglandin E synthase-1 in human gingival fibroblasts. | 2006 Dec |
1 |
| 26 |
17023389 | Shunting of prostanoid biosynthesis in microsomal prostaglandin E synthase-1 null embryo fibroblasts: regulatory effects on inducible nitric oxide synthase expression and nitrite synthesis. | 2006 Nov |
1 |
| 27 |
16081677 | Curcumin suppresses interleukin 1beta-mediated microsomal prostaglandin E synthase 1 by altering early growth response gene 1 and other signaling pathways. | 2005 Nov |
1 |
| 28 |
12941808 | Cooperation of cyclooxygenase 1 and cyclooxygenase 2 in intestinal polyposis. | 2003 Aug 15 |
2 |
| 29 |
14558087 | Prostaglandin E2 is an enhancer of interleukin-1beta-induced expression of membrane-associated prostaglandin E synthase in rheumatoid synovial fibroblasts. | 2003 Oct |
1 |
| 30 |
12233875 | Coexpression of microsomal prostaglandin E synthase with cyclooxygenase-2 in human rheumatoid synovial cells. | 2002 Sep |
1 |
| 31 |
10869354 | Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2. | 2000 Oct 20 |
2 |