| 1 |
34954891 | EHMT1/EHMT2 in EMT, cancer stemness and drug resistance: emerging evidence and mechanisms. | 2022 Mar |
1 |
| 2 |
35634322 | Ethanol Induces Secretion of Proinflammatory Extracellular Vesicles That Inhibit Adult Hippocampal Neurogenesis Through G9a/GLP-Epigenetic Signaling. | 2022 |
1 |
| 3 |
32700783 | Upregulation of histone H3K9 methylation in fetal endothelial cells from preeclamptic pregnancies. | 2021 Mar |
1 |
| 4 |
33153976 | Residues flanking the ARKme3T/S motif allow binding of diverse targets to the HP1 chromodomain: Insights from molecular dynamics simulations. | 2021 Jan |
1 |
| 5 |
33361537 | Oxidative stress-induced aberrant G9a activation disturbs RE-1-containing neuron-specific genes expression, leading to degeneration in human SH-SY5Y neuroblastoma cells. | 2021 Jan 1 |
1 |
| 6 |
33523893 | TBC1D3 promotes neural progenitor proliferation by suppressing the histone methyltransferase G9a. | 2021 Jan |
1 |
| 7 |
33718701 | Mimicking H3 Substrate Arginine in the Design of G9a Lysine Methyltransferase Inhibitors for Cancer Therapy: A Computational Study for Structure-Based Drug Design. | 2021 Mar 9 |
3 |
| 8 |
34010627 | Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development. | 2021 Oct 7 |
1 |
| 9 |
34140780 | G9a Regulates Cell Sensitivity to Radiotherapy via Histone H3 Lysine 9 Trimethylation and CCDC8 in Lung Cancer. | 2021 |
1 |
| 10 |
34168040 | A disproportionate impact of G9a methyltransferase deficiency on the X chromosome. | 2021 Jul 1 |
1 |
| 11 |
34619147 | Heterodimerization of H3K9 histone methyltransferases G9a and GLP activates methyl reading and writing capabilities. | 2021 Nov |
1 |
| 12 |
34681949 | EHMT2/G9a as an Epigenetic Target in Pediatric and Adult Brain Tumors. | 2021 Oct 19 |
2 |
| 13 |
34685453 | Structure, Activity, and Function of the Protein Lysine Methyltransferase G9a. | 2021 Oct 14 |
3 |
| 14 |
34877957 | Amide-derived lysine analogues as substrates and inhibitors of histone lysine methyltransferases and acetyltransferases. | 2021 Dec 22 |
1 |
| 15 |
31756401 | Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening. | 2020 Jan |
3 |
| 16 |
32028644 | EHMT2 Inhibition Induces Cell Death in Human Non-Small Cell Lung Cancer by Altering the Cholesterol Biosynthesis Pathway. | 2020 Feb 3 |
1 |
| 17 |
32684241 | Euchromatin histone methyltransferase II (EHMT2) regulates the expression of ras-related GTP binding C (RRAGC) protein. | 2020 Nov |
1 |
| 18 |
33077425 | Histone Methyltransferase G9a Regulates Expression of Nuclear Receptors and Cytochrome P450 Enzymes in HepaRG Cells at Basal Level and in Fatty Acid Induced Steatosis. | 2020 Dec |
1 |
| 19 |
33088284 | Hypoxia-Inducible Lysine Methyltransferases: G9a and GLP Hypoxic Regulation, Non-histone Substrate Modification, and Pathological Relevance. | 2020 |
3 |
| 20 |
33299050 | Fine-tuning of lysine side chain modulates the activity of histone lysine methyltransferases. | 2020 Dec 9 |
2 |
| 21 |
33330479 | Deficiency of G9a Inhibits Cell Proliferation and Activates Autophagy via Transcriptionally Regulating c-Myc Expression in Glioblastoma. | 2020 |
1 |
| 22 |
30700744 | G9a-dependent histone methylation can be induced in G1 phase of cell cycle. | 2019 Jan 30 |
1 |
| 23 |
30703547 | Epigenetics and memory: Emerging role of histone lysine methyltransferase G9a/GLP complex as bidirectional regulator of synaptic plasticity. | 2019 Mar |
1 |
| 24 |
30710318 | Inhibition of Histone Methyltransferase G9a Attenuates Noise-Induced Cochlear Synaptopathy and Hearing Loss. | 2019 Jun |
3 |
| 25 |
30718920 | Cyclin D1 integrates G9a-mediated histone methylation. | 2019 May |
2 |
| 26 |
30790655 | An augmentation in histone dimethylation at lysine nine residues elicits vision impairment following traumatic brain injury. | 2019 Apr |
1 |
| 27 |
31276898 | Recent progress in histone methyltransferase (G9a) inhibitors as anticancer agents. | 2019 Oct 1 |
2 |
| 28 |
29113759 | Pharmacological and transcriptional inhibition of the G9a histone methyltransferase suppresses proliferation and modulates redox homeostasis in human microvascular endothelial cells. | 2018 Feb |
2 |
| 29 |
29133140 | The histone methyltransferase G9a: a new therapeutic target in biliary tract cancer. | 2018 Feb |
2 |
| 30 |
29774081 | G9a stimulates CRC growth by inducing p53 Lys373 dimethylation-dependent activation of Plk1. | 2018 |
1 |
| 31 |
29805595 | Clinicopathological significance of G9A expression in colorectal carcinoma. | 2018 Jun |
1 |
| 32 |
29855824 | GLP overexpression is associated with poor prognosis in Chronic Lymphocytic Leukemia and its inhibition induces leukemic cell death. | 2018 Oct |
3 |
| 33 |
29860315 | Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration. | 2018 Jul 27 |
1 |
| 34 |
30022091 | MDC1 methylation mediated by lysine methyltransferases EHMT1 and EHMT2 regulates active ATM accumulation flanking DNA damage sites. | 2018 Jul 18 |
1 |
| 35 |
30286792 | Tri-methylation of ATF7IP by G9a/GLP recruits the chromodomain protein MPP8. | 2018 Oct 4 |
3 |
| 36 |
27174055 | G9a - An Appealing Antineoplastic Target. | 2017 |
3 |
| 37 |
28135087 | Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase. | 2017 Mar 9 |
1 |
| 38 |
28301528 | Genome-wide mapping of histone H3K9me2 in acute myeloid leukemia reveals large chromosomal domains associated with massive gene silencing and sites of genome instability. | 2017 |
2 |
| 39 |
28361100 | A novel de novo frameshift deletion in EHMT1 in a patient with Kleefstra Syndrome results in decreased H3K9 dimethylation. | 2017 Mar |
2 |
| 40 |
28443098 | The Lysine Methyltransferase G9a in Immune Cell Differentiation and Function. | 2017 |
3 |
| 41 |
28460359 | Synthesis and biological evaluation of benzimidazole derivatives as the G9a Histone Methyltransferase inhibitors that induce autophagy and apoptosis of breast cancer cells. | 2017 Jun |
3 |
| 42 |
28483947 | Regulation of USP37 Expression by REST-Associated G9a-Dependent Histone Methylation. | 2017 Aug |
1 |
| 43 |
26997278 | Alternative Splicing of G9a Regulates Neuronal Differentiation. | 2016 Mar 29 |
1 |
| 44 |
27056598 | Unexpected Distinct Roles of the Related Histone H3 Lysine 9 Methyltransferases G9a and G9a-Like Protein in Myoblasts. | 2016 Jun 5 |
1 |
| 45 |
27174920 | Inhibition of EHMT2/G9a epigenetically increases the transcription of Beclin-1 via an increase in ROS and activation of NF-κB. | 2016 Jun 28 |
1 |
| 46 |
27606339 | Histone methylation, alternative splicing and neuronal differentiation. | 2016 |
1 |
| 47 |
27874088 | G9a participates in nerve injury-induced Kcna2 downregulation in primary sensory neurons. | 2016 Nov 22 |
1 |
| 48 |
25749385 | G9a is essential for EMT-mediated metastasis and maintenance of cancer stem cell-like characters in head and neck squamous cell carcinoma. | 2015 Mar 30 |
1 |
| 49 |
25978433 | The SUV39H1 inhibitor chaetocin induces differentiation and shows synergistic cytotoxicity with other epigenetic drugs in acute myeloid leukemia cells. | 2015 May 15 |
1 |
| 50 |
26338712 | A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin. | 2015 Oct 23 |
1 |