| 1 |
34593606 | A Novel Therapeutic Strategy Targeting the Mesenchymal Phenotype of Malignant Pleural Mesothelioma by Suppressing LSD1. | 2022 Jan |
5 |
| 2 |
34914972 | HnRNPK and lysine specific histone demethylase-1 regulates IP-10 mRNA stability in monocytes. | 2022 Apr 5 |
1 |
| 3 |
35042538 | 4,5-Dimethoxycanthin-6-one is a novel LSD1 inhibitor that inhibits proliferation of glioblastoma cells and induces apoptosis and pyroptosis. | 2022 Jan 18 |
2 |
| 4 |
35351830 | Evolution Increases Primates Brain Complexity Extending RbFOX1 Splicing Activity to LSD1 Modulation. | 2022 May 4 |
2 |
| 5 |
35487595 | Promising natural lysine specific demethylase 1 inhibitors for cancer treatment: advances and outlooks. | 2022 Apr |
2 |
| 6 |
35504875 | Anti-cancer effect of LINC00478 in bladder cancer correlates with KDM1A-dependent MMP9 demethylation. | 2022 May 3 |
1 |
| 7 |
35636128 | Synthesis, biological evaluation and docking studies of methylene bearing cyanopyrimidine derivatives possessing a hydrazone moiety as potent Lysine specific demethylase-1 (LSD1) inhibitors: A promising anticancer agents. | 2022 Sep |
1 |
| 8 |
32698753 | QSAR Modeling, Molecular Docking and Molecular Dynamics Simulations Studies of Lysine-Specific Demethylase 1 (LSD1) Inhibitors as Anticancer Agents. | 2021 |
1 |
| 9 |
33367935 | Isatin inhibits the invasion and metastasis of SH‑SY5Y neuroblastoma cells in vitro and in vivo. | 2021 Jan |
1 |
| 10 |
33397384 | Histone methyltransferase SUV39H2 regulates LSD1-dependent CDH1 expression and promotes epithelial mesenchymal transition of osteosarcoma. | 2021 Jan 4 |
1 |
| 11 |
33533576 | Synthesis of Carboxamide-Containing Tranylcypromine Analogues as LSD1 (KDM1A) Inhibitors Targeting Acute Myeloid Leukemia. | 2021 Apr 20 |
2 |
| 12 |
33550070 | Target separation and antitumor metastasis activity of sesquiterpene-based lysine-specific demethylase 1 inhibitors from zedoary turmeric oil. | 2021 Mar |
1 |
| 13 |
33581557 | Annual review of LSD1/KDM1A inhibitors in 2020. | 2021 Mar 15 |
2 |
| 14 |
33750776 | Epigenetic modulation reveals differentiation state specificity of oncogene addiction. | 2021 Mar 9 |
1 |
| 15 |
33755924 | First-in-Human Randomized Trial to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of the KDM1A Inhibitor Vafidemstat. | 2021 Mar |
1 |
| 16 |
33799951 | High KDM1A Expression Associated with Decreased CD8+T Cells Reduces the Breast Cancer Survival Rate in Patients with Breast Cancer. | 2021 Mar 7 |
1 |
| 17 |
33823549 | A functional LSD1 coregulator screen reveals a novel transcriptional regulatory cascade connecting R-loop homeostasis with epigenetic regulation. | 2021 May 7 |
1 |
| 18 |
33935733 | Monobenzone, a Novel and Potent KDM1A Inhibitor, Suppresses Migration of Gastric Cancer Cells. | 2021 |
1 |
| 19 |
33986438 | LSD1-mediated demethylation of OCT4 safeguards pluripotent stem cells by maintaining the transcription of PORE-motif-containing genes. | 2021 May 13 |
1 |
| 20 |
34031383 | Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication. | 2021 May 24 |
1 |
| 21 |
34246782 | Combination LSD1 and HOTAIR-EZH2 inhibition disrupts cell cycle processes and induces apoptosis in glioblastoma cells. | 2021 Sep |
2 |
| 22 |
34453478 | In vivo evaluation of the lysine-specific demethylase (KDM1A/LSD1) inhibitor SP-2577 (Seclidemstat) against pediatric sarcoma preclinical models: A report from the Pediatric Preclinical Testing Consortium (PPTC). | 2021 Nov |
2 |
| 23 |
34925656 | KDM1A Identified as a Potential Oncogenic Driver and Prognostic Biomarker via Multi-Omics Analysis. | 2021 |
1 |
| 24 |
34927013 | Comprehensive in Vitro Characterization of the LSD1 Small Molecule Inhibitor Class in Oncology. | 2021 Dec 10 |
2 |
| 25 |
32147995 | [Function of histone demethylasehistone lysine-specific demethylase 1A in tumor initiation and progression]. | 2020 Feb 25 |
1 |
| 26 |
32191225 | The LSD1 inhibitor iadademstat (ORY-1001) targets SOX2-driven breast cancer stem cells: a potential epigenetic therapy in luminal-B and HER2-positive breast cancer subtypes. | 2020 Mar 18 |
2 |
| 27 |
32379508 | LSD1: a viable therapeutic target in cutaneous squamous cell carcinoma? | 2020 Jul |
1 |
| 28 |
32567837 | Nucleosome Binding by the Lysine Specific Demethylase 1 (LSD1) Enzyme Enables Histone H3 Demethylation. | 2020 Jul 14 |
2 |
| 29 |
32647649 | The Histone Lysine-specific Demethylase 1 Inhibitor, SP2509 Exerts Cytotoxic Effects against Renal Cancer Cells through Downregulation of Bcl-2 and Mcl-1. | 2020 Jun 30 |
3 |
| 30 |
32651355 | Long intergenic non-protein-coding RNA 01446 facilitates the proliferation and metastasis of gastric cancer cells through interacting with the histone lysine-specific demethylase LSD1. | 2020 Jul 10 |
1 |
| 31 |
32709337 | Precise separation of lysine-specific demethylase 1 inhibitors from Corydalis yanhusuo using multi-mode counter-current chromatography guided by virtual screening. | 2020 Aug 16 |
1 |
| 32 |
32850370 | LSD1 Promotes Bladder Cancer Progression by Upregulating LEF1 and Enhancing EMT. | 2020 |
1 |
| 33 |
32868907 | Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer. | 2020 Oct |
3 |
| 34 |
32889380 | Capsaicin: A "hot" KDM1A/LSD1 inhibitor from peppers. | 2020 Oct |
2 |
| 35 |
33318631 | LSD1: more than demethylation of histone lysine residues. | 2020 Dec |
2 |
| 36 |
30111819 | Inhibition of histone lysine-specific demethylase 1 elicits breast tumor immunity and enhances antitumor efficacy of immune checkpoint blockade. | 2019 Jan |
1 |
| 37 |
30514804 | Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all-trans retinoic acid in acute myeloid leukemia across subtypes. | 2019 Jun |
2 |
| 38 |
30615537 | Impact of Epigenetic Regulation on Head and Neck Squamous Cell Carcinoma. | 2019 Mar |
1 |
| 39 |
30655368 | Molecular mechanisms of bleeding disorderassociated GFI1BQ287* mutation and its affected pathways in megakaryocytes and platelets. | 2019 Jul |
1 |
| 40 |
30828079 | Lysine-Specific Demethylase 1 (LSD1/KDM1A) Is a Novel Target Gene of c-Myc. | 2019 |
2 |
| 41 |
30846414 | Knockdown of KDM1B inhibits cell proliferation and induces apoptosis of pancreatic cancer cells. | 2019 May |
2 |
| 42 |
30866496 | Expanding the Role of the Histone Lysine-Specific Demethylase LSD1 in Cancer. | 2019 Mar 7 |
1 |
| 43 |
30951900 | Inhibition of lysine-specific demethylase LSD1 induces senescence in Glioblastoma cells through a HIF-1α-dependent pathway. | 2019 May |
1 |
| 44 |
31096156 | Discovery and synthesis of novel indole derivatives-containing 3-methylenedihydrofuran-2(3H)-one as irreversible LSD1 inhibitors. | 2019 Aug 1 |
2 |
| 45 |
31118464 | Regulation of Cholesterol Homeostasis by a Novel Long Non-coding RNA LASER. | 2019 May 22 |
1 |
| 46 |
31205679 | Cytoplasmic translocation of nuclear LSD1 (KDM1A) in human hepatoma cells is induced by its inhibitors. | 2019 Jun 5 |
2 |
| 47 |
31207107 | Catalytic inhibition of KDM1A in Ewing sarcoma is insufficient as a therapeutic strategy. | 2019 Sep |
2 |
| 48 |
31211500 | Knockdown of KDM1A suppresses tumour migration and invasion by epigenetically regulating the TIMP1/MMP9 pathway in papillary thyroid cancer. | 2019 Aug |
4 |
| 49 |
31428587 | LSD1 Activates PI3K/AKT Signaling Through Regulating p85 Expression in Prostate Cancer Cells. | 2019 |
2 |
| 50 |
31435463 | shRNA-interfering LSD1 inhibits proliferation and invasion of gastric cancer cells via VEGF-C/PI3K/AKT signaling pathway. | 2019 Aug 15 |
1 |