Methotrexate

solute carrier family 22 member 8 ; Homo sapiens







24 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35019195 The key role of organic anion transporter 3 in the drug-drug interaction between tranilast and methotrexate. 2022 Apr 1
2 31691080 Coadministration of vindesine with high-dose methotrexate therapy increases acute kidney injury via BCRP, MRP2, and OAT1/OAT3. 2020 Feb 1
3 29285751 Endogenous Metabolites-Mediated Communication Between OAT1/OAT3 and OATP1B1 May Explain the Association Between SLCO1B1 SNPs and Methotrexate Toxicity. 2018 Oct 1
4 29307856 The inhibitory effects of eighteen front-line antibiotics on the substrate uptake mediated by human Organic anion/cation transporters, Organic anion transporting polypeptides and Oligopeptide transporters in in vitro models. 2018 Mar 30 1
5 29353278 Stereoselective Inhibition of Renal Basolateral Human Organic Anion Transporter 3 by Lansoprazole Enantiomers. 2018 2
6 28566636 Inhibition of Methotrexate Uptake via Organic Anion Transporters OAT1 and OAT3 by Glucuronides of Nonsteroidal Anti-inflammatory Drugs. 2017 5
7 28801980 Effects of proton pump inhibitors and famotidine on elimination of plasma methotrexate: Evaluation of drug-drug interactions mediated by organic anion transporter 3. 2017 Dec 6
8 28890383 Interaction between rhein acyl glucuronide and methotrexate based on human organic anion transporters. 2017 Nov 1 1
9 24042472 Characteristics of pemetrexed transport by renal basolateral organic anion transporter hOAT3. 2014 5
10 25239859 Proton pump inhibitors inhibit methotrexate transport by renal basolateral organic anion transporter hOAT3. 2014 Dec 4
11 24036158 Interaction of immunosuppressive drugs with human organic anion transporter (OAT) 1 and OAT3, and multidrug resistance-associated protein (MRP) 2 and MRP4. 2013 Dec 1
12 21440623 In vitro risk assessment of AZD9056 perpetrating a transporter-mediated drug-drug interaction with methotrexate. 2011 May 18 1
13 21457143 Inhibitory effect of selective cyclooxygenase-2 inhibitor etoricoxib on human organic anion transporter 3 (hOAT3). 2011 Apr 4
14 22072415 Stereoselective inhibitory effect of flurbiprofen, ibuprofen and naproxen on human organic anion transporters hOAT1 and hOAT3. 2011 Dec 3
15 20460822 Transport of aminopterin by human organic anion transporters hOAT1 and hOAT3: Comparison with methotrexate. 2010 4
16 20478302 Drug interaction between celecoxib and methotrexate in organic anion transporter 3-transfected renal cells and in rats in vivo. 2010 Aug 25 3
17 20877132 Inhibitory effect of selective cyclooxygenase-2 inhibitor lumiracoxib on human organic anion transporters hOAT1 and hOAT3. 2010 3
18 17660957 Impaired clearance of methotrexate in organic anion transporter 3 (Slc22a8) knockout mice: a gender specific impact of reduced folates. 2008 Feb 4
19 18240155 Enhanced systemic availability of methotrexate in the presence of morin in rats. 2008 May 1
20 18789319 Evaluation of the interaction between nonsteroidal anti-inflammatory drugs and methotrexate using human organic anion transporter 3-transfected cells. 2008 Oct 31 8
21 17578901 Species difference in the inhibitory effect of nonsteroidal anti-inflammatory drugs on the uptake of methotrexate by human kidney slices. 2007 Sep 1
22 15548848 Methotrexate-loxoprofen interaction: involvement of human organic anion transporters hOAT1 and hOAT3. 2004 Oct 6
23 12130730 Characterization of methotrexate transport and its drug interactions with human organic anion transporters. 2002 Aug 7
24 11306713 Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. 2001 May 1