Serine

insulin receptor substrate 1 ; Mus musculus







148 Article(s)
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1 35192202 A novel natural PPARγ agonist, Gypenoside LXXV, ameliorates cognitive deficits by enhancing brain glucose uptake via the activation of Akt/GLUT4 signaling in db/db mice. 2022 Apr 1
2 35508278 Mechanisms by which smoothelin-like protein 1 reverses insulin resistance in myotubules and mice. 2022 Jul 1 3
3 33011364 20-HETE interferes with insulin signaling and contributes to obesity-driven insulin resistance. 2021 Feb 2
4 33326146 Ameliorative effect of persimmon (Diospyros kaki) in cognitively impaired diabetic mice. 2021 Jan 2
5 34234788 Exercise Counterbalances Rho/ROCK2 Signaling Impairment in the Skeletal Muscle and Ameliorates Insulin Sensitivity in Obese Mice. 2021 1
6 31981662 Hypoglycaemic effect and mechanism of an RG-II type polysaccharide purified from Aconitum coreanum in diet-induced obese mice. 2020 Apr 15 1
7 32432228 Insulin Signal Transduction is Impaired in the Type 2 Diabetic Retina. 2020 1
8 32714408 Compound Danshen Dripping Pills Prevented Leptin Deficiency-Induced Hepatic ER Stress, Stimulated Autophagy, and Improved Insulin Resistance of ob/ob Mice. 2020 1
9 33303821 Saturated fatty acids induce insulin resistance in podocytes through inhibition of IRS1 via activation of both IKKβ and mTORC1. 2020 Dec 10 3
10 30629257 Transgenerational Effects of Periconception Heavy Metal Administration on Adipose Weight and Glucose Homeostasis in Mice at Maturity. 2019 Apr 1 2
11 30964050 Involvement of insulin receptor substrates in cognitive impairment and Alzheimer's disease. 2019 Aug 1
12 31095431 Glucose Homeostasis following Diesel Exhaust Particulate Matter Exposure in a Lung Epithelial Cell-Specific IKK2-Deficient Mouse Model. 2019 May 1
13 31233775 The hepatic-targeted, resveratrol loaded nanoparticles for relief of high fat diet-induced nonalcoholic fatty liver disease. 2019 Aug 10 1
14 31339708 γ-Glutamylvaline Prevents Low-Grade Chronic Inflammation via Activation of a Calcium-Sensing Receptor Pathway in 3T3-L1Mouse Adipocytes. 2019 Jul 31 1
15 31426549 Serine Phosphorylation of IRS1 Correlates with Aβ-Unrelated Memory Deficits and Elevation in Aβ Level Prior to the Onset of Memory Decline in AD. 2019 Aug 17 9
16 31464308 Gymnemic acid alleviates inflammation and insulin resistance via PPARδ- and NFκB-mediated pathways in db/db mice. 2019 Sep 1 1
17 28984034 Microcystin-LR disrupts insulin signaling by hyperphosphorylating insulin receptor substrate 1 and glycogen synthase. 2018 Jan 3
18 29339083 miRNA15a regulates insulin signal transduction in the retinal vasculature. 2018 Apr 2
19 29374854 Liraglutide ameliorates palmitate-induced insulin resistance through inhibiting the IRS-1 serine phosphorylation in mouse skeletal muscle cells. 2018 Sep 2
20 29433422 The effect of noise exposure on insulin sensitivity in mice may be mediated by the JNK/IRS1 pathway. 2018 Feb 12 1
21 29496905 Control of hyperglycemia in male mice by leflunomide: mechanisms of action. 2018 Apr 2
22 29778537 A new indanedione derivative alleviates symptoms of diabetes by modulating RAGE-NF-kappaB pathway in db/db mice. 2018 Jul 2 2
23 29789397 The Wnt antagonist and secreted frizzled-related protein 5: implications on lipid metabolism, inflammation, and type 2 diabetes mellitus. 2018 Aug 31 2
24 29988567 Metformin treatment ameliorates diabetes-associated decline in hippocampal neurogenesis and memory via phosphorylation of insulin receptor substrate 1. 2018 Jul 1
25 30030460 Uncaria tomentosa improves insulin sensitivity and inflammation in experimental NAFLD. 2018 Jul 20 1
26 30043179 Programming of central and peripheral insulin resistance by low birthweight and postnatal catch-up growth in male mice. 2018 Oct 1
27 30050584 QiDiTangShen Granules Reduced Diabetic Kidney Injury by Regulating the Phosphorylation Balance of the Tyrosine and Serine Residues of Insulin Receptor Substrate 1. 2018 2
28 30316815 PPARγ is a major regulator of branched-chain amino acid blood levels and catabolism in white and brown adipose tissues. 2018 Dec 1
29 27462872 Nandinine, a Derivative of Berberine, Inhibits Inflammation and Reduces Insulin Resistance in Adipocytes via Regulation of AMP-Kinase Activity. 2017 Feb 1
30 27771511 High fat diet induces brain insulin resistance and cognitive impairment in mice. 2017 Feb 1
31 28334990 Insulin resistance and exendin-4 treatment for multiple system atrophy. 2017 May 1 1
32 28338397 Clove and Its Active Compound Attenuate Free Fatty Acid-Mediated Insulin Resistance in Skeletal Muscle Cells and in Mice. 2017 Apr 2
33 28386117 Overexpression of matrix metalloproteinase-9 (MMP-9) rescues insulin-mediated impairment in the 5XFAD model of Alzheimer's disease. 2017 Apr 6 2
34 28550243 Apomorphine Therapy for Neuronal Insulin Resistance in a Mouse Model of Alzheimer's Disease. 2017 2
35 28870245 Mice overexpressing growth hormone exhibit increased skeletal muscle myostatin and MuRF1 with attenuation of muscle mass. 2017 Sep 4 3
36 28941626 Deletion of protein tyrosine phosphatase 1B obliterates endoplasmic reticulum stress-induced myocardial dysfunction through regulation of autophagy. 2017 Dec 1
37 29490521 Toll-like receptor 4 regulates insulin signal transduction in retinal Müller cells. 2017 Dec 2
38 25594850 Role of Mig-6 in hepatic glucose metabolism. 2016 Jan 1
39 26827782 Phycocyanin ameliorates alloxan-induced diabetes mellitus in mice: Involved in insulin signaling pathway and GK expression. 2016 Mar 5 1
40 26846849 Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase. 2016 Apr 15 3
41 26926180 Corosolic acid inhibits adipose tissue inflammation and ameliorates insulin resistance via AMPK activation in high-fat fed mice. 2016 Feb 15 2
42 27746687 Ginsenoside Rb1 and compound K improve insulin signaling and inhibit ER stress-associated NLRP3 inflammasome activation in adipose tissue. 2016 Oct 1
43 27872488 PLD1 regulates adipogenic differentiation through mTOR - IRS-1 phosphorylation at serine 636/639. 2016 Nov 22 4
44 30023489 Macrophage-Mediated Effects of Airborne Fine Particulate Matter (PM2.5) on Hepatocyte Insulin Resistance in Vitro. 2016 Nov 30 1
45 25381390 Hypochlorous acid via peroxynitrite activates protein kinase Cθ and insulin resistance in adipocytes. 2015 Feb 6
46 25706874 LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes. 2015 Mar 1
47 26079879 Melatonin inhibits tunicamycin-induced endoplasmic reticulum stress and insulin resistance in skeletal muscle cells. 2015 Aug 7 3
48 26112408 Lipid-induced Muscle Insulin Resistance Is Mediated by GGPPS via Modulation of the RhoA/Rho Kinase Signaling Pathway. 2015 Aug 14 1
49 26449763 Paradoxical effect of rapamycin on inflammatory stress-induced insulin resistance in vitro and in vivo. 2015 Oct 9 1
50 26474286 IGF-1 mediated phosphorylation of specific IRS-1 serines in Ames dwarf fibroblasts is associated with longevity. 2015 Nov 3 6