Potassium

potassium voltage-gated channel subfamily Q member 1 ; Homo sapiens







94 Article(s)
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1 35629795 Investigating Structural Dynamics of KCNE3 in Different Membrane Environments Using Molecular Dynamics Simulations. 2022 Apr 27 1
2 33373586 KCNE1 is an auxiliary subunit of two distinct ion channel superfamilies. 2021 Jan 21 1
3 33498651 Molecular Mechanism of Autosomal Recessive Long QT-Syndrome 1 without Deafness. 2021 Jan 23 4
4 33535882 Specific protein kinase C isoform exerts chronic inhibition on the slowly activating delayed-rectifier potassium current by affecting channel trafficking. 2021 Dec 1
5 31785237 PKCβII specifically regulates KCNQ1/KCNE1 channel membrane localization. 2020 Jan 1
6 31825788 The membrane protein KCNQ1 potassium ion channel: Functional diversity and current structural insights. 2020 May 1 1
7 31834838 Physical and functional interaction sites in cytoplasmic domains of KCNQ1 and KCNE1 channel subunits. 2020 Feb 1 1
8 31919767 Characterization and functional roles of KCNQ-encoded voltage-gated potassium (Kv7) channels in human corpus cavernosum smooth muscle. 2020 Jan 1
9 32270035 The unconventional biogenesis of Kv7.1-KCNE1 complexes. 2020 Apr 2
10 32338831 Rottlerin: Structure Modifications and KCNQ1/KCNE1 Ion Channel Activity. 2020 Jun 17 2
11 30918124 I Ks ion-channel pore conductance can result from individual voltage sensor movements. 2019 Apr 16 1
12 30967788 Investigating the Complex Arrhythmic Phenotype Caused by the Gain-of-Function Mutation KCNQ1-G229D. 2019 4
13 31236320 Gating modulation of the KCNQ1 channel by KCNE proteins studied by voltage-clamp fluorometry. 2019 2
14 31461851 Regulation of IKs Potassium Current by Isoproterenol in Adult Cardiomyocytes Requires Type 9 Adenylyl Cyclase. 2019 Aug 27 1
15 31803246 The Identification of Differentially Expressed Genes Showing Aberrant Methylation Patterns in Pheochromocytoma by Integrated Bioinformatics Analysis. 2019 1
16 31946488 Pharmacotherapeutic Effects of Quinidine on Short QT Syndrome by Using Purkinje-Ventricle Model: A Simulation Study. 2019 Jul 1
17 28193246 Possible mechanisms for sensorineural hearing loss and deafness in patients with propionic acidemia. 2017 Feb 13 1
18 28233402 Probing the interaction of the potassium channel modulating KCNE1 in lipid bilayers via solid-state NMR spectroscopy. 2017 Aug 1
19 28976808 Ca2+-Calmodulin and PIP2 interactions at the proximal C-terminus of Kv7 channels. 2017 Nov 2 2
20 25444851 Microscopic mechanisms for long QT syndrome type 1 revealed by single-channel analysis of I(Ks) with S3 domain mutations in KCNQ1. 2015 Feb 1
21 25712016 Identification of a key residue in Kv7.1 potassium channel essential for sensing external potassium ions. 2015 Mar 1
22 23844633 LQTS in Northern BC: homozygosity for KCNQ1 V205M presents with a more severe cardiac phenotype but with minimal impact on auditory function. 2014 Jul 1
23 24357532 KCNQ1 long QT syndrome patients have hyperinsulinemia and symptomatic hypoglycemia. 2014 Apr 4
24 24721657 Recent molecular insights from mutated IKS channels in cardiac arrhythmia. 2014 Apr 1
25 24947509 Novel Kv7.1-phosphatidylinositol 4,5-bisphosphate interaction sites uncovered by charge neutralization scanning. 2014 Aug 15 1
26 25037568 Long QT mutations at the interface between KCNQ1 helix C and KCNE1 disrupt I(KS) regulation by PKA and PIP₂. 2014 Sep 15 1
27 23424208 Probucol and the cholesterol synthesis inhibitors simvastatin and triparanol regulate I ks channel function differently. 2013 Oct 1
28 24190995 Intracellular ATP binding is required to activate the slowly activating K+ channel I(Ks). 2013 Nov 19 1
29 24314077 Building KCNQ1/KCNE1 channel models and probing their interactions by molecular-dynamics simulations. 2013 Dec 3 2
30 22095730 Dominant-negative control of cAMP-dependent IKs upregulation in human long-QT syndrome type 1. 2012 Jan 20 4
31 22508963 Pro-arrhythmogenic effects of the S140G KCNQ1 mutation in human atrial fibrillation - insights from modelling. 2012 Sep 15 1
32 22745159 Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channel. 2012 Jul 17 2
33 22778270 The A-kinase anchoring protein Yotiao facilitates complex formation between adenylyl cyclase type 9 and the IKs potassium channel in heart. 2012 Aug 24 3
34 22908235 KCNQ1 channels do not undergo concerted but sequential gating transitions in both the absence and the presence of KCNE1 protein. 2012 Oct 5 1
35 23000022 Impaired ion channel function related to a common KCNQ1 mutation - implications for risk stratification in long QT syndrome 1. 2012 Dec 10 1
36 21059661 The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure. 2011 Jan 7 2
37 21084310 Characterization of a binding site for anionic phospholipids on KCNQ1. 2011 Jan 21 1
38 21241800 Biophysical properties of mutant KCNQ1 S277L channels linked to hereditary long QT syndrome with phenotypic variability. 2011 Apr 1
39 21895724 A dual mechanism for I(Ks) current reduction by the pathogenic mutation KCNQ1-S277L. 2011 Dec 3
40 21915266 Drosophila KCNQ channel displays evolutionarily conserved electrophysiology and pharmacology with mammalian KCNQ channels. 2011 1
41 22073228 N-terminal arginines modulate plasma-membrane localization of Kv7.1/KCNE1 channel complexes. 2011 1
42 19907016 Mechanisms of disease pathogenesis in long QT syndrome type 5. 2010 Feb 1
43 19913547 The rate-dependent biophysical properties of the LQT1 H258R mutant are counteracted by a dominant negative effect on channel trafficking. 2010 Jun 3
44 20139709 KCNQ1/KCNE1 assembly, co-translation not required. 2010 Mar-Apr 1
45 20348026 Trafficking-competent KCNQ1 variably influences the function of HERG long QT alleles. 2010 Jul 1
46 20399767 Ginsenoside Rg3 activates human KCNQ1 K+ channel currents through interacting with the K318 and V319 residues: a role of KCNE1 subunit. 2010 Jul 10 5
47 20421371 Mechanistic basis for LQT1 caused by S3 mutations in the KCNQ1 subunit of IKs. 2010 May 1
48 20436212 Action potential clamp and mefloquine sensitivity of recombinant 'I KS' channels incorporating the V307L KCNQ1 mutation. 2010 Apr 1
49 20660394 Patient-specific induced pluripotent stem-cell models for long-QT syndrome. 2010 Oct 7 1
50 18536934 The gastric HK-ATPase: structure, function, and inhibition. 2009 Jan 1