Poly I-C

DExD/H-box helicase 58 ; Homo sapiens







31 Article(s)
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Pub. Year
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1 35594991 Discovery proteomics analysis determines that driver oncogenes suppress antiviral defense pathways through reduction in interferon-b autocrine stimulation. 2022 May 17 2
2 32491861 Combined Intranasal Nanoemulsion and RIG-I Activating RNA Adjuvants Enhance Mucosal, Humoral, and Cellular Immunity to Influenza Virus. 2021 Feb 1 2
3 33402460 PolyIC Induces Retinoic Acid-inducible Gene-I and Melanoma Differentiation-associated Gene 5 and Modulates Inflammation in Podocytes. 2021 Jan-Feb 5
4 33459340 Opposite actions of two dsRNA-binding proteins PACT and TRBP on RIG-I mediated signaling. 2021 Feb 12 2
5 34729315 Cytosolic delivery of the immunological adjuvant Poly I:C and cytotoxic drug crystals via a carrier-free strategy significantly amplifies immune response. 2021 Oct 1
6 30808838 Cytosolic Sensors of Viral RNA Are Involved in the Production of Interleukin-6 via Toll-Like Receptor 3 Signaling in Human Glomerular Endothelial Cells. 2019 1
7 31046839 Immunotherapeutic effects of intratumoral nanoplexed poly I:C. 2019 May 2 1
8 29496994 Fascin1 suppresses RIG-I-like receptor signaling and interferon-β production by associating with IκB kinase ϵ (IKKϵ) in colon cancer. 2018 Apr 27 1
9 30179292 Innate immune sensor laboratory of genetics and physiology 2 suppresses tumor cell growth and functions as a prognostic marker in neuroblastoma. 2018 Nov 1
10 28109979 Interferon (IFN)-induced protein 35 (IFI35) negatively regulates IFN-β-phosphorylated STAT1-RIG-I-CXCL10/CCL5 axis in U373MG astrocytoma cells treated with polyinosinic-polycytidylic acid. 2017 Mar 1 1
11 28794402 DEC1 negatively regulates the expression of CXCL10 and CCL5 induced by poly IC in normal human mesangial cells. 2017 2
12 25469248 Effects of ionizing radiation on retinoic acid-inducible gene-I-like receptors. 2015 Jan 3
13 25803620 Differential responses of normal human melanocytes to intra- and extracellular dsRNA. 2015 Jun 1
14 26208481 MDA5 complements TLR3 in suppression of neuroblastoma. 2015 Sep 22 4
15 26283481 Stimulation of the RIG-I/MAVS Pathway by Polyinosinic:Polycytidylic Acid Upregulates IFN-β in Airway Epithelial Cells with Minimal Costimulation of IL-8. 2015 Sep 15 1
16 23648811 Small non-coding RNAs encoded within the herpes simplex virus type 1 latency associated transcript (LAT) cooperate with the retinoic acid inducible gene I (RIG-I) to induce beta-interferon promoter activity and promote cell survival. 2013 Aug 2
17 23911868 Length of dsRNA (poly I:C) drives distinct innate immune responses, depending on the cell type. 2013 Nov 1
18 22198151 A synthetic double-stranded RNA, poly I:C, induces a rapid apoptosis of human CD34(+) cells. 2012 Apr 1
19 22590509 Triggering of the dsRNA sensors TLR3, MDA5, and RIG-I induces CD55 expression in synovial fibroblasts. 2012 2
20 22973045 Double-stranded RNA induces biphasic STAT1 phosphorylation by both type I interferon (IFN)-dependent and type I IFN-independent pathways. 2012 Dec 1
21 23062195 Poly I:C-induced tumor cell apoptosis mediated by pattern-recognition receptors. 2012 Nov 2
22 21130742 Contribution of IPS-1 to polyI:C-induced cytokine production in conjunctival epithelial cells. 2011 Jan 7 1
23 21715345 Inhibition of TLR3-mediated proinflammatory effects by Alkylphosphocholines in human retinal pigment epithelial cells. 2011 Aug 17 1
24 21832855 Polyinosinic-polycytidylic acid induces the expression of interferon-stimulated gene 20 in mesangial cells. 2011 1
25 20639488 TLR3 and Rig-like receptor on myeloid dendritic cells and Rig-like receptor on human NK cells are both mandatory for production of IFN-gamma in response to double-stranded RNA. 2010 Aug 15 1
26 20930504 Anticancer function of polyinosinic-polycytidylic acid. 2010 Dec 15 6
27 19007809 Identification of an Atlantic salmon IFN multigene cluster encoding three IFN subtypes with very different expression properties. 2009 Apr 1
28 19154402 Polyinosinic-polycytidylic acid liposome induces human hepatoma cells apoptosis which correlates to the up-regulation of RIG-I like receptors. 2009 Mar 1
29 17928888 IFN-alpha enhances poly-IC responses in human keratinocytes by inducing expression of cytosolic innate RNA receptors: relevance for psoriasis. 2008 Apr 1
30 18471880 Signal regulatory protein alpha negatively regulates both TLR3 and cytoplasmic pathways in type I interferon induction. 2008 Jun 1
31 19669308 Increased expression of Toll-like receptor 3 in intrahepatic biliary epithelial cells at sites of ductular reaction in diseased livers. 2008 Jun 2