11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene

interleukin 1 receptor associated kinase 1 ; Homo sapiens







8 Article(s)
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1 33402387 Targeting the IRAK1-S100A9 Axis Overcomes Resistance to Paclitaxel in Nasopharyngeal Carcinoma. 2021 Mar 1 2
2 33232476 Determining the recommended dose of pacritinib: results from the PAC203 dose-finding trial in advanced myelofibrosis. 2020 Nov 24 1
3 33275766 Pacritinib demonstrates spleen volume reduction in patients with myelofibrosis independent of JAK2V617F allele burden. 2020 Dec 8 1
4 29235894 Pacritinib and its use in the treatment of patients with myelofibrosis who have thrombocytopenia. 2018 Apr 1
5 29616317 Outcomes of patients with myelofibrosis treated with compassionate use pacritinib: a sponsor-independent international study. 2018 Aug 2
6 29743719 Inhibition of interleukin-1 receptor-associated kinase-1 is a therapeutic strategy for acute myeloid leukemia subtypes. 2018 Nov 6
7 29785143 Pilot study of the antifibrotic effects of the multikinase inhibitor pacritinib in a mouse model of liver fibrosis. 2018 1
8 27931243 Phase 1/2 study of pacritinib, a next generation JAK2/FLT3 inhibitor, in myelofibrosis or other myeloid malignancies. 2016 Dec 8 2