fludarabine

signal transducer and activator of transcription 1 ; Homo sapiens







45 Article(s)
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1 33125792 Interferon-γ decreases ATP-binding cassette subfamily G member 1-mediated cholesterol efflux through small ubiquitin-like modifier/ubiquitin-dependent liver X receptor-α degradation in macrophages. 2021 Dec 2
2 33238771 STAT1 participates in the induction of substance P expression in airway epithelial cells by respiratory syncytial virus. 2021 Feb-Mar 1
3 33300108 Drug-repositioning screening identified fludarabine and risedronic acid as potential therapeutic compounds for malignant pleural mesothelioma. 2021 Jun 1
4 34297045 Mantle cell lymphoma polarizes tumor-associated macrophages into M2-like macrophages, which in turn promote tumorigenesis. 2021 Jul 27 1
5 34414234 Dexmedetomidine Directs T Helper Cells toward Th1 Cell Differentiation via the STAT1-T-Bet Pathway. 2021 1
6 34445570 Kahweol Exerts Skin Moisturizing Activities by Upregulating STAT1 Activity. 2021 Aug 18 2
7 34462423 VAV2 is required for DNA repair and implicated in cancer radiotherapy resistance. 2021 Aug 30 1
8 34508746 Interleukin-35 inhibits lipopolysaccharide-induced endothelial cell activation by downregulating inflammation and apoptosis. 2021 Oct 15 2
9 32945463 IFN‑γ induces apoptosis in human melanocytes by activating the JAK1/STAT1 signaling pathway. 2020 Oct 2
10 30078219 Role of STAT signaling and autocrine action of chemokines during H2 O 2 induced HTR-8/SVneo trophoblastic cells invasion. 2019 Feb 1
11 30674474 Hypomethylation of STAT1 and HLA-DRB1 is associated with type-I interferon-dependent HLA-DRB1 expression in lupus CD8+ T cells. 2019 Apr 1
12 31196186 Deferasirox drives ROS-mediated differentiation and induces interferon-stimulated gene expression in human healthy haematopoietic stem/progenitor cells and in leukemia cells. 2019 Jun 13 1
13 31333586 Dapagliflozin Attenuates Renal Tubulointerstitial Fibrosis Associated With Type 1 Diabetes by Regulating STAT1/TGFβ1 Signaling. 2019 1
14 31427448 Functional Characterization of an Interferon Gamma Receptor-Like Protein on Entamoeba histolytica. 2019 Nov 1
15 31772586 miR-129-5p Regulates the Immunomodulatory Functions of Adipose-Derived Stem Cells via Targeting Stat1 Signaling. 2019 1
16 29796115 miR-29c plays a suppressive role in breast cancer by targeting the TIMP3/STAT1/FOXO1 pathway. 2018 1
17 29990747 MicroRNA-193b-3p regulates hepatocyte apoptosis in selenium-deficient broilers by targeting MAML1. 2018 Sep 2
18 28552376 Involvement of STAT1 in proliferation and invasiveness of trophoblastic cells. 2017 Sep 2
19 28881584 Dimerization of EGFR and HER2 induces breast cancer cell motility through STAT1-dependent ACTA2 induction. 2017 Aug 1 1
20 26255980 Gain-of-function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC). 2015 Oct 1
21 26497667 Inhibition of integrin β1 decreases the malignancy of ovarian cancer cells and potentiates anticancer therapy via the FAK/STAT1 signaling pathway. 2015 Dec 1
22 24335311 STAT1 interaction with E3-14.7K in monocytes affects the efficacy of oncolytic adenovirus. 2014 Feb 1
23 24911872 Fludarabine downregulates indoleamine 2,3-dioxygenase in tumors via a proteasome-mediated degradation mechanism. 2014 1
24 24211327 In silico simulations of STAT1 and STAT3 inhibitors predict SH2 domain cross-binding specificity. 2013 Nov 15 5
25 22479354 Interferon-α regulates glutaminase 1 promoter through STAT1 phosphorylation: relevance to HIV-1 associated neurocognitive disorders. 2012 1
26 26105330 PP007. Effects of STAT1 suppression on ERK1/2 in trophoblastic cells. 2012 Jul 5
27 21752694 STAT1 as a novel therapeutical target in pro-atherogenic signal integration of IFNγ, TLR4 and IL-6 in vascular disease. 2011 Aug 2
28 20435158 Induction of indoleamine 2,3-dioxygenase by interferon-gamma in human lens epithelial cells: apoptosis through the formation of 3-hydroxykynurenine. 2010 Sep 1
29 19100922 Radiosensitization by inhibiting STAT1 in renal cell carcinoma. 2009 Jan 1 3
30 19103208 HIV-1 gp120 induces cytokine expression, leukocyte adhesion, and transmigration across the blood-brain barrier: modulatory effects of STAT1 signaling. 2009 Mar 1
31 19404407 Type I interferons and interferon regulatory factors regulate TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected macrophages. 2009 1
32 18003888 STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier. 2008 Feb 15 1
33 18054268 Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through activation of the Jak2 tyrosine kinase pathway in vascular endothelial cells. 2008 2
34 17072862 STAT1 signaling is associated with acquired crossresistance to doxorubicin and radiation in myeloma cell lines. 2007 Jan 1 1
35 17179173 Inhibition of interleukin 1-induced matrix metalloproteinase 13 expression in human chondrocytes by interferon gamma. 2007 Jun 1
36 16380218 Functional characterization of human osteoclast inhibitory peptide-1 (OIP-1/hSca) gene promoter. 2006 Apr 12 1
37 15621835 Role of the STAT1 pathway in apoptosis induced by fludarabine and JAK kinase inhibitors in B-cell chronic lymphocytic leukemia. 2005 Mar 2
38 14654078 Oral fludarabine has significant activity in patients with previously untreated chronic lymphocytic leukemia, and leads to increased STAT1 levels in vivo. 2004 Feb 3
39 15022320 MEK/ERK and signal transducer and activator of transcription signaling pathways modulate oncostatin M-stimulated CCL2 expression in human osteoblasts through a common transcription factor. 2004 Mar 1
40 15217838 Differential roles of STAT1alpha and STAT1beta in fludarabine-induced cell cycle arrest and apoptosis in human B cells. 2004 Oct 15 1
41 12085225 Resistance to fludarabine-induced apoptosis in Epstein-Barr virus infected B cells. 2002 Jul 4 1
42 11556541 Cathepsins are upregulated by IFN-gamma/STAT1 in human muscle culture: a possible active factor in dermatomyositis. 2001 Sep 2
43 10637471 Serine/threonine phosphorylation in cytokine signal transduction. 2000 Jan 1
44 10906175 Lentivirus infection in the brain induces matrix metalloproteinase expression: role of envelope diversity. 2000 Aug 1
45 10202937 Fludarabine-induced immunosuppression is associated with inhibition of STAT1 signaling. 1999 Apr 6