Serine

interleukin 6 ; Homo sapiens







56 Article(s)
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1 34826187 JNK-mediated Ser27 phosphorylation and stabilization of SIRT1 promote growth and progression of colon cancer through deacetylation-dependent activation of Snail. 2022 Apr 1
2 33711835 Simultaneous Quantitative Detection of IL-6 and PCT Using SERS magnetic immunoassay with sandwich structure. 2021 Mar 31 3
3 33885657 Rapid, highly sensitive and quantitative detection of interleukin 6 based on SERS magnetic immunoassay. 2021 Apr 22 2
4 33972660 FMRP regulates STAT3 mRNA localization to cellular protrusions and local translation to promote hepatocellular carcinoma metastasis. 2021 May 10 1
5 34544857 Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells. 2021 Sep 28 6
6 34682865 Diosmetin Induces Modulation of Igf-1 and Il-6 Levels to Alter Rictor-Akt-PKCα Cascade in Inhibition of Prostate Cancer. 2021 Oct 15 2
7 32786691 Serum Proteomics in COVID-19 Patients: Altered Coagulation and Complement Status as a Function of IL-6 Level. 2020 Nov 6 1
8 31001483 BAG3 Suppresses Loading of Ago2 to IL6 mRNA in Pancreatic Ductal Adenocarcinoma. 2019 6
9 27716424 Anti-inflammatory effects of Salvia plebeia R. Br extract in vitro and in ovalbumin-induced mouse model. 2016 Oct 5 1
10 24487064 A non-canonical function of eukaryotic elongation factor 1A1: regulation of interleukin-6 expression. 2014 May 1
11 20974848 IL-6-induced enhancement of c-Myc translation in multiple myeloma cells: critical role of cytoplasmic localization of the rna-binding protein hnRNP A1. 2011 Jan 7 2
12 20978825 Adiponectin reduces C-reactive protein expression and downregulates STAT3 phosphorylation induced by IL-6 in HepG2 cells. 2011 Jan 1
13 21474440 Glucocorticoid-independent repression of tumor necrosis factor (TNF) alpha-stimulated interleukin (IL)-6 expression by the glucocorticoid receptor: a potential mechanism for protection against an excessive inflammatory response. 2011 Jun 3 1
14 20379953 Kansuinine A and Kansuinine B from Euphorbia kansui L. inhibit IL-6-induced Stat3 activation. 2010 Oct 1
15 19009233 The fungal secondary metabolite trichodimerol inhibits TGF-β dependent cellular effects and tube formation of MDA-MB-231 cells. 2009 Dec 1
16 19038492 Identification of genes, including the gene encoding p27Kip1, regulated by serine 276 phosphorylation of the p65 subunit of NF-kappaB. 2009 Mar 8 1
17 19182994 Ha-ras oncogene-induced Stat3 phosphorylation enhances oncogenicity of the cell. 2009 Mar 2
18 19365107 Gly80Ser polymorphism of phospholipase A2-IID is associated with cytokine inducibility in A549 cells. 2009 2
19 19670249 Prostasin regulates iNOS and cyclin D1 expression by modulating protease-activated receptor-2 signaling in prostate epithelial cells. 2009 Dec 1 1
20 19885032 Extracellular Signal-regulated Kinase Activation Is Required for Serine 727 Phosphorylation of STAT3 in Schwann Cells in vitro and in vivo. 2009 Jun 4
21 17993646 Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway. 2008 Jan 11 2
22 18204781 Phosphorylation and nuclear translocation of STAT3 regulated by the Epstein-Barr virus latent membrane protein 1 in nasopharyngeal carcinoma. 2008 Feb 1
23 19026125 IL-6 receptor, IL-8 receptor and TNF-alpha238 (G/A) polymorphisms are not associated with Behçet's disease in patients of German or Turkish origin. 2008 Jul-Aug 1
24 19074889 IL-6-induced stimulation of c-myc translation in multiple myeloma cells is mediated by myc internal ribosome entry site function and the RNA-binding protein, hnRNP A1. 2008 Dec 15 1
25 17242212 Interleukin-6 impairs the insulin signaling pathway, promoting production of nitric oxide in human umbilical vein endothelial cells. 2007 Mar 3
26 17703129 Can the protective actions of JAK-STAT in the heart be exploited therapeutically? Parsing the regulation of interleukin-6-type cytokine signaling. 2007 Aug 1
27 16362041 Identification of MEKK2/3 serine phosphorylation site targeted by the Toll-like receptor and stress pathways. 2006 Jan 11 1
28 16467451 IL-6 haplotypes, inflammation, and risk for cardiovascular disease in a multiethnic dialysis cohort. 2006 Mar 1
29 16714289 Prostaglandin E2 stimulates p53 transactivational activity through specific serine 15 phosphorylation in human synovial fibroblasts. Role in suppression of c/EBP/NF-kappaB-mediated MEKK1-induced MMP-1 expression. 2006 Jul 21 1
30 17258468 STAT1 and STAT3 phosphorylation by porins are independent of JAKs but are dependent on MAPK pathway and plays a role in U937 cells production of interleukin-6. 2006 Dec 1
31 15764709 STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylation. 2005 Mar 22 3
32 15940250 Accelerated proliferation of myeloma cells by interleukin-6 cooperating with fibroblast growth factor receptor 3-mediated signals. 2005 Sep 15 1
33 12496440 House dust mite Dermatophagoides farinae augments proinflammatory mediator productions and accessory function of alveolar macrophages: implications for allergic sensitization and inflammation. 2003 Jan 1 1
34 12710894 Reduction of serum C-reactive protein by statin therapy may reflect decreased isoprenylation of Rac-1, a mediator of the IL-6 signal transduction pathway. 2003 May 3
35 11270639 Interleukin-6 up-regulates the oxytocin receptor in cultured uterine smooth muscle cells. 2001 Mar 1
36 11335711 Sequential activation of Rac-1, SEK-1/MKK-4, and protein kinase Cdelta is required for interleukin-6-induced STAT3 Ser-727 phosphorylation and transactivation. 2001 Jul 20 4
37 11429693 The YXXQ motif in gp 130 is crucial for STAT3 phosphorylation at Ser727 through an H7-sensitive kinase pathway. 2001 Jun 14 1
38 10636920 Activation of the Stat3 signaling pathway is required for differentiation by interleukin-6 in PC12-E2 cells. 2000 Jan 21 2
39 10727406 Interleukin-6-induced STAT3 transactivation and Ser727 phosphorylation involves Vav, Rac-1 and the kinase SEK-1/MKK-4 as signal transduction components. 2000 Apr 1 3
40 11027495 Inhibition of interleukin-6 signaling and Stat3 activation by a new class of bioactive cyclopentenone derivatives. 2000 Sep 24 1
41 11056211 Inhibition of interleukin-6 signaling by galiellalactone. 2000 Oct 27 1
42 10446219 Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner. 1999 Aug 20 3
43 9466577 Synovial fibroblasts and the sphingomyelinase pathway: sphingomyelin turnover and ceramide generation are not signaling mechanisms for the actions of tumor necrosis factor-alpha. 1998 Feb 1
44 9558728 Interleukin-6 and related cytokines: effect on the acute phase reaction. 1998 2
45 9736697 Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases. 1998 Sep 15 2
46 9808569 Thymocyte contact or monoclonal antibody-mediated clustering of 3beta1 or 6beta4 integrins activate interleukin-6 (IL-6) transcription factors (NF-kappaB and NF-IL6) and IL-6 production in human thymic epithelial cells. 1998 Nov 15 2
47 9343414 STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation. 1997 Nov 1
48 8621406 A di-leucine motif and an upstream serine in the interleukin-6 (IL-6) signal transducer gp130 mediate ligand-induced endocytosis and down-regulation of the IL-6 receptor. 1996 Mar 8 3
49 8706672 Participation of two Ser-Ser-Phe-Tyr repeats in interleukin-6 (IL-6)-binding sites of the human IL-6 receptor. 1996 Jun 15 6
50 7533107 Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction. 1995 Feb 27 4