2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

interleukin 6 ; Homo sapiens







73 Article(s)
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1 34725715 β2-Adrenoceptor Activation Stimulates IL-6 Production via PKA, ERK1/2, Src, and Beta-Arrestin2 Signaling Pathways in Human Bronchial Epithelia. 2021 Dec 1
2 33228785 Cyr61 synthesis is induced by interleukin-6 and promotes migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis. 2020 Nov 23 1
3 30724633 Silica nanoparticles as an enhancer in the IL-1β-induced inflammation cycle of A549 cells. 2019 Apr 1
4 31322196 Effect of S100A8 and S100A9 on expressions of cytokine and skin barrier protein in human keratinocytes. 2019 Sep 1
5 28328292 IL-6 is involved in malignancy and doxorubicin sensitivity of renal carcinoma cells. 2018 Jan 2 2
6 30007092 Upregulation of IL-6 expression in human salivary gland cell line by IL-17 via activation of p38 MAPK, ERK, PI3K/Akt, and NF-κB pathways. 2018 Oct 1
7 26431069 Induction of proinflammatory cytokine production in intervertebral disc cells by macrophage-like THP-1 cells requires mitogen-activated protein kinase activity. 2016 Jan 1
8 25715004 Latanoprost-induced Cytokine and Chemokine Release From Human Tenon's Capsule Fibroblasts: Role of MAPK and NF-κB Signaling Pathways. 2015 Dec 1
9 25738264 Testosterone enhances lipopolysaccharide-induced interleukin-6 and macrophage chemotactic protein-1 expression by activating the extracellular signal-regulated kinase 1/2/nuclear factor-κB signalling pathways in 3T3-L1 adipocytes. 2015 Jul 1
10 23161148 Neuroprotection of interleukin-6 against NMDA-induced neurotoxicity is mediated by JAK/STAT3, MAPK/ERK, and PI3K/AKT signaling pathways. 2013 Mar 2
11 22087578 IL-6 and soluble IL-6 receptor stimulate the production of MMPs and their inhibitors via JAK-STAT and ERK-MAPK signalling in human chondrocytes. 2012 Apr 1 1
12 22110547 Mechanisms of Edible Bird's Nest Extract-Induced Proliferation of Human Adipose-Derived Stem Cells. 2012 1
13 20739465 TRPV1 activation is required for hypertonicity-stimulated inflammatory cytokine release in human corneal epithelial cells. 2011 Jan 1
14 21123455 IL-6 trans-signaling in formation and progression of malignant ascites in ovarian cancer. 2011 Jan 15 1
15 21172926 Advanced glycation end products induce the expression of interleukin-6 and interleukin-8 by receptor for advanced glycation end product-mediated activation of mitogen-activated protein kinases and nuclear factor-κB in human osteoarthritis chondrocytes. 2011 May 1
16 21288261 P2 porin and loop L7 from Haemophilus influenzae modulate expression of IL-6 and adhesion molecules in astrocytes. 2011 May 1
17 21757746 Cholangiocyte N-Ras protein mediates lipopolysaccharide-induced interleukin 6 secretion and proliferation. 2011 Sep 2 1
18 19823118 Lipoteichoic acid-induced TNF-α and IL-6 gene expressions and oxidative stress production in macrophages are suppressed by ketamine through downregulating Toll-like receptor 2-mediated activation oF ERK1/2 and NFκB. 2010 May 2
19 19923143 Bradykinin and high glucose promote renal tubular inflammation. 2010 Mar 2
20 20375905 Interleukin-6 inhibits endothelial nitric oxide synthase activation and increases endothelial nitric oxide synthase binding to stabilized caveolin-1 in human vascular endothelial cells. 2010 May 2
21 20731619 Roles of MAPK pathway activation during cytokine induction in BEAS-2B cells exposed to fine World Trade Center (WTC) dust. 2010 Oct-Dec 1
22 18825409 Regulation of TLR4-induced IL-6 response in bladder cancer cells by opposing actions of MAPK and PI3K signaling. 2009 Mar 1
23 19011039 Interleukin-6 stimulation of growth of prostate cancer in vitro and in vivo through activation of the androgen receptor. 2009 Mar 1
24 19061939 Neuroprotection of interleukin-6 against NMDA attack and its signal transduction by JAK and MAPK. 2009 Jan 30 3
25 19438975 Porphyromonas gingivalis fimbriae-dependent interleukin-6 autocrine regulation by increase of gp130 in endothelial cells. 2009 Aug 1
26 19494504 Intracellular protein phosphorylation in eosinophils and the functional relevance in cytokine production. 2009 1
27 18177344 Mycoplasma genitalium-derived lipid-associated membrane proteins induce activation of MAPKs, NF-kappaB and AP-1 in THP-1 cells. 2008 Mar 2
28 18660424 Cytokine, chemokine, and adhesion molecule expression mediated by MAPKs in human corneal fibroblasts exposed to poly(I:C). 2008 Aug 1
29 19016005 Interleukin-6 stimulates lipolysis in porcine adipocytes. 2008 Jun 1
30 19034873 Albumin induces interleukin-6 release from primary human proximal tubule epithelial cells. 2008 Nov-Dec 1
31 17178391 Highly homologous Mycobacterium tuberculosis chaperonin 60 proteins with differential CD14 dependencies stimulate cytokine production by human monocytes through cooperative activation of p38 and ERK1/2 mitogen-activated protein kinases. 2007 Feb 1
32 17267401 Insulin antagonizes interleukin-6 signaling and is anti-inflammatory in 3T3-L1 adipocytes. 2007 Mar 30 1
33 17761160 Cooperation of calcineurin and ERK for UTP-induced IL-6 production in HaCaT keratinocytes. 2007 Nov 14 1
34 17876544 Inflammatory responses induced by interleukin-17 family members in human colonic subepithelial myofibroblasts. 2007 Sep 1
35 16516857 Interleukin-6 triggers human cerebral endothelial cells proliferation and migration: the role for KDR and MMP-9. 2006 Apr 21 1
36 15611272 Activation of cytokine production by secreted phospholipase A2 in human lung macrophages expressing the M-type receptor. 2005 Jan 1 1
37 16003000 Carbon monoxide inhibits IL-17-induced IL-6 production through the MAPK pathway in human pulmonary epithelial cells. 2005 Aug 1
38 14737074 Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis. 2004 Mar 2
39 14998552 Inhibition of p38 and ERK MAP kinases blocks endotoxin-induced nitric oxide production and differentially modulates cytokine expression. 2004 May 1
40 15129368 The interleukin-6/soluble interleukin-6 receptor system induces parathyroid hormone-related protein in human osteoblastic cells. 2004 Aug 2
41 15345332 Activation of osteoblastic functions by a mediator of pain, bradykinin. 2004 Oct 1 1
42 15363595 Iron-induced interleukin-6 gene expression: possible mediation through the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways. 2004 Oct 15 1
43 12505790 Interferon-gamma induces C/EBP beta expression and activity through MEK/ERK and p38 in T84 colon epithelial cells. 2003 May 1
44 12595539 JAK2/STAT3, not ERK1/2, mediates interleukin-6-induced activation of inducible nitric-oxide synthase and decrease in contractility of adult ventricular myocytes. 2003 May 2 1
45 12915102 Coal-induced interleukin-6 gene expression is mediated through ERKs and p38 MAPK pathways. 2003 Aug 15 1
46 14586407 Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways. 2003 Oct 30 1
47 11891214 Activation of extracellular signal-regulated kinase (ERK)1/2, but not p38 and c-Jun N-terminal kinase, is involved in signaling of a novel cytokine, ML-1. 2002 May 3 1
48 12016129 IL-17 stimulates inflammatory responses via NF-kappaB and MAP kinase pathways in human colonic myofibroblasts. 2002 Jun 1
49 12115737 Transcription factors C/EBP-beta and -delta regulate IL-6 production in IL-1beta-stimulated human enterocytes. 2002 Jul 1
50 12183057 Extracellular signal-regulated kinases 1 and 2 participate in interleukin-17 plus tumor necrosis factor-alpha-induced stabilization of interleukin-6 mRNA in human pancreatic myofibroblasts. 2002 Aug 19 1