Lysine

histone deacetylase 8 ; Homo sapiens







12 Article(s)
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Pub. Year
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1 33827976 A selective HDAC8 inhibitor potentiates antitumor immunity and efficacy of immune checkpoint blockade in hepatocellular carcinoma. 2021 Apr 7 2
2 33998791 Comparative QM/MM Molecular Dynamics and Umbrella Sampling Simulations: Interaction of the Zinc-Bound Intermediate Gem-Diolate Trapoxin A Inhibitor and Acetyl-l-lysine Substrate with Histone Deacetylase 8. 2021 May 27 2
3 34917889 Kinetic Characterization of Human Histone Deacetylase 8 With Medium-Chain Fatty Acyl Lysine. 2021 2
4 30358439 HDAC8 inhibition ameliorates pulmonary fibrosis. 2019 Jan 1 1
5 30054507 Histone deacetylase 8 protects human proximal tubular epithelial cells from hypoxia-mimetic cobalt- and hypoxia/reoxygenation-induced mitochondrial fission and cytotoxicity. 2018 Jul 27 1
6 28509866 HDAC8 Prevents Anthrax Lethal Toxin-induced Cell Cycle Arrest through Silencing PTEN in Human Monocytic THP-1 Cells. 2017 May 16 1
7 27459069 HDAC8 Catalyzes the Hydrolysis of Long Chain Fatty Acyl Lysine. 2016 Oct 21 3
8 27933794 Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8. 2016 Dec 6 2
9 26383163 Histone Deacetylase HDAC8 Promotes Insulin Resistance and β-Catenin Activation in NAFLD-Associated Hepatocellular Carcinoma. 2015 Nov 15 1
10 22272142 Dynamic structure-based pharmacophore model development: a new and effective addition in the histone deacetylase 8 (HDAC8) inhibitor discovery. 2011 2
11 20870437 Docking-enabled pharmacophore model for histone deacetylase 8 inhibitors and its application in anti-cancer drug discovery. 2010 Nov 1
12 14701748 Negative regulation of histone deacetylase 8 activity by cyclic AMP-dependent protein kinase A. 2004 Jan 1