Dexamethasone

BCL2 like 11 ; Homo sapiens







17 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35205731 Chemotherapy-Free Targeted Anti-BCR-ABL+ Acute Lymphoblastic Leukemia Therapy May Benefit the Heart. 2022 Feb 15 1
2 32242100 Reversal of glucocorticoid resistance in paediatric acute lymphoblastic leukaemia is dependent on restoring BIM expression. 2020 Jun 2
3 30598523 Akt2 mediates glucocorticoid resistance in lymphoid malignancies through FoxO3a/Bim axis and serves as a direct target for resistance reversal. 2019 Jan 1 3
4 28529032 Synergistic Cytotoxicity of Lenalidomide and Dexamethasone in Mantle Cell Lymphoma via Cereblon-dependent Targeting of the IL-6/STAT3/PI3K Axis. 2017 Jun 1
5 25336632 Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells. 2015 Jan 8 2
6 26231047 Obatoclax is a direct and potent antagonist of membrane-restricted Mcl-1 and is synthetic lethal with treatment that induces Bim. 2015 Aug 1 2
7 26376801 FOXO3a and Posttranslational Modifications Mediate Glucocorticoid Sensitivity in B-ALL. 2015 Dec 1
8 22825467 Glucocorticoid-mediated BIM induction and apoptosis are regulated by Runx2 and c-Jun in leukemia cells. 2012 Jul 19 11
9 21047686 Lenalidomide synergizes with dexamethasone to induce growth arrest and apoptosis of mantle cell lymphoma cells in vitro and in vivo. 2011 Mar 1
10 19914305 Bim is the key mediator of glucocorticoid-induced apoptosis and of its potentiation by rapamycin in human myeloma cells. 2010 Feb 9
11 20067466 Glutathione S-transferase M1 inhibits dexamethasone-induced apoptosis in association with the suppression of Bim through dual mechanisms in a lymphoblastic leukemia cell line. 2010 Mar 3
12 21121775 Quantitative analysis and modeling of glucocorticoid-controlled gene expression. 2010 Nov 1
13 19404317 MEK inhibitors potentiate dexamethasone lethality in acute lymphoblastic leukemia cells through the pro-apoptotic molecule BIM. 2009 Oct 3
14 19559478 Dexamethasone-induced apoptosis and up-regulation of Bim is dependent on glycogen synthase kinase-3. 2009 Dec 3
15 18064628 Regulation of bim in glucocorticoid-mediated osteoblast apoptosis. 2008 May 5
16 18515658 Dexamethasone-induced apoptotic mechanisms in myeloma cells investigated by analysis of mutant glucocorticoid receptors. 2008 Aug 15 2
17 16309671 Inhibition of PI3-kinase-Akt pathway enhances dexamethasone-induced apoptosis in a human follicular lymphoma cell line. 2006 Feb 1 1