| 1 |
32844279 | The pro-apoptotic domain of BIM protein forms toxic amyloid fibrils. | 2021 Mar |
1 |
| 2 |
34478517 | Heterogeneous modulation of Bcl-2 family members and drug efflux mediate MCL-1 inhibitor resistance in multiple myeloma. | 2021 Oct 26 |
2 |
| 3 |
30501963 | BH3 mimetics derived from Bim-BH3 domain core region show PTP1B inhibitory activity. | 2019 Jan 15 |
3 |
| 4 |
30860026 | Bim escapes displacement by BH3-mimetic anti-cancer drugs by double-bolt locking both Bcl-XL and Bcl-2. | 2019 Mar 12 |
2 |
| 5 |
31408950 | Activating the Intrinsic Pathway of Apoptosis Using BIM BH3 Peptides Delivered by Peptide Amphiphiles with Endosomal Release. | 2019 Aug 12 |
1 |
| 6 |
29053589 | Structural and Functional Insight into Canarypox Virus CNP058 Mediated Regulation of Apoptosis. | 2017 Oct 20 |
1 |
| 7 |
29340082 | Reciprocal sensitivity of diffuse large B-cell lymphoma cells to Bcl-2 inhibitors BIRD-2 versus venetoclax. | 2017 Dec 19 |
1 |
| 8 |
26486506 | BAK is a predictive and prognostic biomarker for the therapeutic effect of docetaxel treatment in patients with advanced gastric cancer. | 2016 Jul |
1 |
| 9 |
26640142 | Targeting glutamine metabolism in multiple myeloma enhances BIM binding to BCL-2 eliciting synthetic lethality to venetoclax. | 2016 Jul 28 |
1 |
| 10 |
27661108 | Acquired resistance to venetoclax (ABT-199) in t(14;18) positive lymphoma cells. | 2016 Oct 25 |
1 |
| 11 |
25174872 | IL-10/Janus kinase/signal transducer and activator of transcription 3 signaling dysregulates Bim expression in autoimmune lymphoproliferative syndrome. | 2015 Mar |
1 |
| 12 |
26447615 | Targeting ERK1/2-bim signaling cascades by BH3-mimetic ABT-737 as an alternative therapeutic strategy for oral cancer. | 2015 Nov 3 |
1 |
| 13 |
24825889 | Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-β. | 2014 May 27 |
1 |
| 14 |
23234544 | The BH3 mimetic ABT-263 synergizes with the MEK1/2 inhibitor selumetinib/AZD6244 to promote BIM-dependent tumour cell death and inhibit acquired resistance. | 2013 Mar 1 |
1 |
| 15 |
23243017 | Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism. | 2013 Feb 15 |
1 |
| 16 |
22355769 | Bak Conformational Changes Induced by Ligand Binding: Insight into BH3 Domain Binding and Bak Homo-Oligomerization. | 2012 |
2 |
| 17 |
22622039 | A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers. | 2012 Jun |
1 |
| 18 |
21148306 | The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner. | 2011 Mar 18 |
3 |
| 19 |
21628457 | Multiple BH3 mimetics antagonize antiapoptotic MCL1 protein by inducing the endoplasmic reticulum stress response and up-regulating BH3-only protein NOXA. | 2011 Jul 15 |
1 |
| 20 |
20074640 | Refining the minimal sequence required for ERK1/2-dependent poly-ubiquitination and proteasome-dependent turnover of BIM. | 2010 May |
1 |
| 21 |
20160166 | Apoptosis induced by JAK2 inhibition is mediated by Bim and enhanced by the BH3 mimetic ABT-737 in JAK2 mutant human erythroid cells. | 2010 Apr 8 |
1 |
| 22 |
19557009 | Bax activation by Bim? | 2009 Sep |
1 |
| 23 |
18843207 | A novel Bim-BH3-derived Bcl-XL inhibitor: biochemical characterization, in vitro, in vivo and ex-vivo anti-leukemic activity. | 2008 Oct |
4 |
| 24 |
16645638 | Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets. | 2007 Jan |
1 |
| 25 |
17389404 | Structural insights into the degradation of Mcl-1 induced by BH3 domains. | 2007 Apr 10 |
1 |
| 26 |
9430630 | Bim: a novel member of the Bcl-2 family that promotes apoptosis. | 1998 Jan 15 |
1 |