Sorafenib

platelet derived growth factor receptor alpha ; Homo sapiens







17 Article(s)
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Title
Pub. Year
#Total Relationships
1 34875133 Detection of gene mutations and gene-gene fusions in circulating cell-free DNA of glioblastoma patients: an avenue for clinically relevant diagnostic analysis. 2022 May 1
2 33376527 Genome-wide prioritization reveals novel gene signatures associated with cardiotoxic effects of tyrosine kinase inhibitors. 2021 Feb 1
3 30318721 Prolonged response to sorafenib in a patient with refractory metastatic osteosarcoma and a somatic PDGFRA D846V mutation. 2019 Jan 1
4 21396851 Prognostic prediction in patients with metastatic renal cell carcinoma treated with sorafenib based on expression levels of potential molecular markers in radical nephrectomy specimens. 2013 Jan 1
5 23243060 Induction of endoplasmic reticulum stress by sorafenib and activation of NF-κB by lestaurtinib as a novel resistance mechanism in Hodgkin lymphoma cell lines. 2013 Feb 1
6 24324073 Small molecule-based chemotherapeutic approach in p16-positive and -negative HNSCC in vitro. 2013 Dec 2
7 21818111 Limited clinical activity of nilotinib and sorafenib in FIP1L1-PDGFRA positive chronic eosinophilic leukemia with imatinib-resistant T674I mutation. 2012 Jan 1
8 22294526 Clinical activity of sorafenib in patients with advanced gastrointestinal stromal tumor bearing PDGFRA exon 18 mutation: a case series. 2012 Mar 1
9 22406992 Sorafenib and HDAC inhibitors synergize to kill CNS tumor cells. 2012 May 1
10 22665524 Sorafenib inhibits many kinase mutations associated with drug-resistant gastrointestinal stromal tumors. 2012 Aug 3
11 22821509 The role of insulin-like growth factors signaling in merlin-deficient human schwannomas. 2012 Nov 1
12 21727212 Nilotinib alone or in combination with selumetinib is a drug candidate for neurofibromatosis type 2. 2011 Jul 1
13 20726440 Identification and characterization of novel oncogenes in chronic eosinophilic leukemia and T-cell acute lymphoblastic leukemia. 2010 3
14 19210352 A novel FIP1L1-PDGFRA mutant destabilizing the inactive conformation of the kinase domain in chronic eosinophilic leukemia/hypereosinophilic syndrome. 2009 Jun 3
15 19212337 FIP1L1-PDGFRalpha D842V, a novel panresistant mutant, emerging after treatment of FIP1L1-PDGFRalpha T674I eosinophilic leukemia with single agent sorafenib. 2009 May 1
16 17846009 [Angiogenesis and renal cell carcinoma]. 2007 Jul 2
17 16645167 Sorafenib is a potent inhibitor of FIP1L1-PDGFRalpha and the imatinib-resistant FIP1L1-PDGFRalpha T674I mutant. 2006 Aug 15 1