| 1 |
34708329 | SIRT6 Negatively Regulates Schwann Cells Dedifferentiation via Targeting c-Jun During Wallerian Degeneration After Peripheral Nerve Injury. | 2022 Jan |
4 |
| 2 |
35172823 | Clinicopathological and prognostic value of SIRT6 in patients with solid tumors: a meta-analysis and TCGA data review. | 2022 Feb 16 |
2 |
| 3 |
35256952 | Targeting a cryptic allosteric site of SIRT6 with small-molecule inhibitors that inhibit the migration of pancreatic cancer cells. | 2022 Feb |
1 |
| 4 |
35278642 | SIRT6 serves as a polyhedron in glycolytic metabolism and ageing-related diseases. | 2022 Jun 1 |
4 |
| 5 |
35457169 | Neuroprotective Potential of Dendritic Cells and Sirtuins in Multiple Sclerosis. | 2022 Apr 14 |
1 |
| 6 |
32541922 | MDL-800, an allosteric activator of SIRT6, suppresses proliferation and enhances EGFR-TKIs therapy in non-small cell lung cancer. | 2021 Jan |
4 |
| 7 |
33440786 | Mono(ADP-ribosyl)ation Enzymes and NAD+ Metabolism: A Focus on Diseases and Therapeutic Perspectives. | 2021 Jan 11 |
1 |
| 8 |
33619381 | A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma. | 2021 Feb |
1 |
| 9 |
33800266 | The Two-Faced Role of SIRT6 in Cancer. | 2021 Mar 8 |
2 |
| 10 |
33920726 | A Comprehensive Analysis into the Therapeutic Application of Natural Products as SIRT6 Modulators in Alzheimer's Disease, Aging, Cancer, Inflammation, and Diabetes. | 2021 Apr 17 |
2 |
| 11 |
34094839 | Mechanism of allosteric activation of SIRT6 revealed by the action of rationally designed activators. | 2021 May |
2 |
| 12 |
34213345 | Emerging Therapeutic Potential of SIRT6 Modulators. | 2021 Jul 22 |
2 |
| 13 |
34239868 | SIRT6 Promotes Osteogenic Differentiation of Adipose-Derived Mesenchymal Stem Cells Through Antagonizing DNMT1. | 2021 |
4 |
| 14 |
34573442 | Mammalian SIRT6 Represses Invasive Cancer Cell Phenotypes through ATP Citrate Lyase (ACLY)-Dependent Histone Acetylation. | 2021 Sep 21 |
1 |
| 15 |
34731617 | Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis. | 2021 Nov 2 |
2 |
| 16 |
34787870 | Decreased serum SIRT6 as a novel predictor of coronary artery disease. | 2021 Nov |
1 |
| 17 |
34906231 | SIRT6 inhibition delays peripheral nerve recovery by suppressing migration, phagocytosis and M2-polarization of macrophages. | 2021 Dec 14 |
4 |
| 18 |
34950960 | Roles of SIRT6 in kidney disease: a novel therapeutic target. | 2021 Dec 24 |
1 |
| 19 |
31822559 | Mechanism of activation for the sirtuin 6 protein deacylase. | 2020 Jan 31 |
1 |
| 20 |
32236974 | Robust expression of SIRT6 inhibits pulpitis via activation of the TRPV1 channel. | 2020 Jul |
3 |
| 21 |
32283646 | Structural Insight into the Interactions between Structurally Similar Inhibitors and SIRT6. | 2020 Apr 9 |
2 |
| 22 |
32483423 | Small-molecule activating SIRT6 elicits therapeutic effects and synergistically promotes anti-tumor activity of vitamin D3 in colorectal cancer. | 2020 |
4 |
| 23 |
32518153 | Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators. | 2020 Aug 7 |
2 |
| 24 |
33087267 | NAD+-mediated regulation of mammalian base excision repair. | 2020 Sep |
2 |
| 25 |
30514106 | SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells. | 2019 Mar |
1 |
| 26 |
30655890 | SIRT6 inhibits proliferation and invasion in osteosarcoma cells by targeting N-cadherin. | 2019 Jan |
1 |
| 27 |
30885209 | NF-κB upregulates glutamine-fructose-6-phosphate transaminase 2 to promote migration in non-small cell lung cancer. | 2019 Mar 18 |
1 |
| 28 |
31005557 | Sirtuin 6 inhibits MWCNTs-induced epithelial-mesenchymal transition in human bronchial epithelial cells via inactivating TGF-β1/Smad2 signaling pathway. | 2019 Jul 1 |
4 |
| 29 |
31844103 | Structural basis for the activation and inhibition of Sirtuin 6 by quercetin and its derivatives. | 2019 Dec 16 |
2 |
| 30 |
29363378 | Downregulation of SIRT6 is associated with poor prognosis in patients with non-small cell lung cancer. | 2018 Apr |
8 |
| 31 |
29512698 | Downregulation of SIRT6 by miR-34c-5p is associated with poor prognosis and promotes colon cancer proliferation through inhibiting apoptosis via the JAK2/STAT3 signaling pathway. | 2018 May |
2 |
| 32 |
29874586 | Increased Amino Acid Uptake Supports Autophagy-Deficient Cell Survival upon Glutamine Deprivation. | 2018 Jun 5 |
1 |
| 33 |
29966233 | A Review of the Recent Advances Made with SIRT6 and its Implications on Aging Related Processes, Major Human Diseases, and Possible Therapeutic Targets. | 2018 Jun 29 |
4 |
| 34 |
30250025 | Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells. | 2018 Sep 24 |
2 |
| 35 |
30670969 | SIRT6 Suppresses NFATc4 Expression and Activation in Cardiomyocyte Hypertrophy. | 2018 |
1 |
| 36 |
27766571 | Strong Correlation between the Expression Levels of HDAC4 and SIRT6 in Hematological Malignancies of the Adults. | 2017 Jul |
2 |
| 37 |
28355567 | SIRT6 Is Essential for Adipocyte Differentiation by Regulating Mitotic Clonal Expansion. | 2017 Mar 28 |
1 |
| 38 |
28656307 | SIRT6 inhibits growth of gastric cancer by inhibiting JAK2/STAT3 pathway. | 2017 Aug |
1 |
| 39 |
28887543 | The Oxidative State of Cysteine Thiol 144 Regulates the SIRT6 Glucose Homeostat. | 2017 Sep 8 |
2 |
| 40 |
28958848 | SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects. | 2017 Oct 15 |
1 |
| 41 |
26675349 | Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells. | 2016 Mar 3 |
2 |
| 42 |
26717993 | The complex role of SIRT6 in carcinogenesis. | 2016 Feb |
1 |
| 43 |
26886147 | Sequence Variants of SIRT6 Gene Promoter in Myocardial Infarction. | 2016 Apr |
1 |
| 44 |
26898756 | A crucial role of SUMOylation in modulating Sirt6 deacetylation of H3 at lysine 56 and its tumor suppressive activity. | 2016 Sep 15 |
1 |
| 45 |
27180906 | SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b. | 2016 Jun 2 |
2 |
| 46 |
27767101 | Oxidative stress dependent microRNA-34a activation via PI3Kα reduces the expression of sirtuin-1 and sirtuin-6 in epithelial cells. | 2016 Oct 21 |
1 |
| 47 |
25288139 | Epigenetic modulation of chronic anxiety and pain by histone deacetylation. | 2015 Oct |
2 |
| 48 |
25404738 | Sequential actions of SIRT1-RELB-SIRT3 coordinate nuclear-mitochondrial communication during immunometabolic adaptation to acute inflammation and sepsis. | 2015 Jan 2 |
1 |
| 49 |
25807436 | The histone deacetylase SIRT6 inhibits ovarian cancer cell proliferation via down-regulation of Notch 3 expression. | 2015 |
1 |
| 50 |
25819580 | Depletion of SIRT6 causes cellular senescence, DNA damage, and telomere dysfunction in human chondrocytes. | 2015 Aug |
1 |