Wortmannin

insulin receptor substrate 1 ; Homo sapiens







12 Article(s)
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Title
Pub. Year
#Total Relationships
1 20936651 Comparison of intracellular signalling by insulin and the hypermitogenic AspB10 analogue in MCF-7 breast adenocarcinoma cells. 2011 May 1
2 18501560 Leptin induces IL-8 expression via leptin receptor, IRS-1, PI3K, Akt cascade and promotion of NF-kappaB/p300 binding in human synovial fibroblasts. 2008 Aug 1
3 17617622 Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-kappaB, and p300 pathway in microglia. 2007 Jul 15 1
4 15713122 Mechanism of feedback regulation of insulin receptor substrate-1 phosphorylation in primary adipocytes. 2005 Jun 1 1
5 11875115 14-3-3 facilitates insulin-stimulated intracellular trafficking of insulin receptor substrate 1. 2002 Mar 1
6 11147790 Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation. 2001 Jan 2
7 10830273 Persistent activation of phosphatidylinositol 3-kinase causes insulin resistance due to accelerated insulin-induced insulin receptor substrate-1 degradation in 3T3-L1 adipocytes. 2000 Jun 1
8 10497255 Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function. 1999 Oct 1 2
9 9761740 Phosphatidylinositol 3'-kinase associates with an insulin receptor substrate-1 serine kinase distinct from its intrinsic serine kinase. 1998 Oct 15 1
10 9036989 Activation of the phosphatidylinositol 3-kinase serine kinase by IFN-alpha. 1997 Mar 1 1
11 8660383 Differential regulation of insulin-stimulated tyrosine phosphorylation of IRS-1 and SHC by Wortmannin in intact cells. 1996 Jun 5 6
12 7695630 Normal activation of p70 S6 kinase by insulin in cells overexpressing dominant negative 85kD subunit of phosphoinositide 3-kinase. 1995 Mar 17 2