| 1 |
35108527 | Gene silencing by EZH2 suppresses TGF-β activity within the decidua to avert pregnancy-adverse wound healing at the maternal-fetal interface. | 2022 Feb 1 |
1 |
| 2 |
35500243 | Design and Synthesis of Dual EZH2/BRD4 Inhibitors to Target Solid Tumors. | 2022 May 12 |
1 |
| 3 |
32772228 | The Role of EZH2 Inhibitor, GSK-126, in Seizure Susceptibility. | 2021 Mar |
1 |
| 4 |
33414441 | Loss of EHF facilitates the development of treatment-induced neuroendocrine prostate cancer. | 2021 Jan 5 |
1 |
| 5 |
33608392 | EZH2 is required for parathyroid and thymic development through differentiation of the third pharyngeal pouch endoderm. | 2021 Mar 1 |
1 |
| 6 |
33632299 | Chromatin remodeling by the histone methyltransferase EZH2 drives lung pre-malignancy and is a target for cancer prevention. | 2021 Feb 25 |
2 |
| 7 |
34031939 | EZH2-mediated inhibition of KLF14 expression promotes HSCs activation and liver fibrosis by downregulating PPARγ. | 2021 Jul |
1 |
| 8 |
34144503 | Ezh2 knockout in mesenchymal cells causes enamel hyper-mineralization. | 2021 Aug 27 |
2 |
| 9 |
34224844 | High glucose-stimulated enhancer of zeste homolog-2 (EZH2) forces suppression of deptor to cause glomerular mesangial cell pathology. | 2021 Oct |
1 |
| 10 |
34344022 | Spatial transcriptomics analysis of uterine gene expression in enhancer of zeste homolog 2 conditional knockout mice†. | 2021 Nov 15 |
1 |
| 11 |
34409953 | LINC01232 Promotes Gastric Cancer Proliferation through Interacting with EZH2 to Inhibit the Transcription of KLF2. | 2021 Oct 28 |
2 |
| 12 |
34600894 | DZNep protects against retinal ganglion cell death in an NMDA-induced mouse model of retinal degeneration. | 2021 Nov |
1 |
| 13 |
34930462 | DZNep promotes mouse bone defect healing via enhancing both osteogenesis and osteoclastogenesis. | 2021 Dec 20 |
2 |
| 14 |
34937916 | Selective EZH2 inhibitor zld1039 alleviates inflammation in cisplatin-induced acute kidney injury partially by enhancing RKIP and suppressing NF-κB p65 pathway. | 2021 Dec 22 |
2 |
| 15 |
31914694 | Enhancer of zeste homolog 2 modulates oxidative stress-mediated pyroptosis in vitro and in a mouse kidney ischemia-reperfusion injury model. | 2020 Jan |
2 |
| 16 |
32094206 | Ezh2 Represses Transcription of Innate Lymphoid Genes in B Lymphocyte Progenitors and Maintains the B-2 Cell Fate. | 2020 Apr 1 |
1 |
| 17 |
32553389 | EZH2 is involved in vulnerability to neuroinflammation and depression-like behaviors induced by chronic stress in different aged mice. | 2020 Jul 1 |
2 |
| 18 |
32562311 | Inhibition of EZH2 alleviates angiogenesis in a model of corneal neovascularization by blocking FoxO3a-mediated oxidative stress. | 2020 Aug |
2 |
| 19 |
32731005 | EZH2 expression and its role in spermatogonial stem cell self-renewal in goats. | 2020 Oct 1 |
2 |
| 20 |
32906688 | Combination Treatment with GSK126 and Pomalidomide Induces B-Cell Differentiation in EZH2 Gain-of-Function Mutant Diffuse Large B-Cell Lymphoma. | 2020 Sep 7 |
1 |
| 21 |
33016573 | Critical regulation of a NDIME/MEF2C axis in embryonic stem cell neural differentiation and autism. | 2020 Nov 5 |
2 |
| 22 |
30954472 | Enhancer of Zeste 2 Polycomb Repressive Complex 2 Subunit Is Required for Uterine Epithelial Integrity. | 2019 Jun |
1 |
| 23 |
30971429 | Enhancer of zeste homolog 2 (EZH2) regulates adipocyte lipid metabolism independent of adipogenic differentiation: Role of apolipoprotein E. | 2019 May 24 |
2 |
| 24 |
31070797 | Proteasomal Degradation of Enhancer of Zeste Homologue 2 in Cholangiocytes Promotes Biliary Fibrosis. | 2019 Nov |
1 |
| 25 |
31534051 | Inhibition of EZH2 methyltransferase decreases immunoediting of mesothelioma cells by autologous macrophages through a PD-1-dependent mechanism. | 2019 Sep 19 |
2 |
| 26 |
31592235 | P21 and P27 promote tumorigenesis and progression via cell cycle acceleration in seminal vesicles of TRAMP mice. | 2019 |
3 |
| 27 |
29244146 | Ezh2 Mutations Found in the Weaver Overgrowth Syndrome Cause a Partial Loss of H3K27 Histone Methyltransferase Activity. | 2018 Apr 1 |
2 |
| 28 |
29288200 | EZH2 Represses the B Cell Transcriptional Program and Regulates Antibody-Secreting Cell Metabolism and Antibody Production. | 2018 Feb 1 |
1 |
| 29 |
29415998 | Homocysteine activates autophagy by inhibition of CFTR expression via interaction between DNA methylation and H3K27me3 in mouse liver. | 2018 Feb 7 |
2 |
| 30 |
29466371 | Ezh2 is not required for cardiac regeneration in neonatal mice. | 2018 |
1 |
| 31 |
29632530 | Ezh2 Regulates Activation-Induced CD8+ T Cell Cycle Progression via Repressing Cdkn2a and Cdkn1c Expression. | 2018 |
1 |
| 32 |
29775417 | Targeting histone methyltransferase enhancer of zeste homolog-2 inhibits renal epithelial-mesenchymal transition and attenuates renal fibrosis. | 2018 May 18 |
2 |
| 33 |
29789597 | Enhancer of zeste homolog 2-catalysed H3K27 trimethylation plays a key role in acute-on-chronic liver failure via TNF-mediated pathway. | 2018 May 22 |
2 |
| 34 |
29899112 | Enhancer of zeste homolog 2 (Ezh2) controls bone formation and cell cycle progression during osteogenesis in mice. | 2018 Aug 17 |
2 |
| 35 |
30172749 | Long noncoding RNA HOTAIR promotes the self-renewal of leukemia stem cells through epigenetic silencing of p15. | 2018 Nov |
1 |
| 36 |
30257200 | Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue Regeneration. | 2018 Sep 25 |
1 |
| 37 |
30305391 | The deletion of the protein phosphatase 1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2. | 2018 Nov 23 |
1 |
| 38 |
30327434 | Loss of histone methyltransferase Ezh2 stimulates an osteogenic transcriptional program in chondrocytes but does not affect cartilage development. | 2018 Dec 7 |
1 |
| 39 |
30341286 | Targeting enhancer of zeste homolog 2 protects against acute kidney injury. | 2018 Oct 19 |
2 |
| 40 |
28223321 | A non-canonical function of Ezh2 preserves immune homeostasis. | 2017 Apr |
1 |
| 41 |
28246193 | Hsp90 inhibition destabilizes Ezh2 protein in alloreactive T cells and reduces graft-versus-host disease in mice. | 2017 May 18 |
1 |
| 42 |
29101351 | Programmed cell senescence in skeleton during late puberty. | 2017 Nov 3 |
1 |
| 43 |
26307668 | Suppression of EZH2 Prevents the Shift of Osteoporotic MSC Fate to Adipocyte and Enhances Bone Formation During Osteoporosis. | 2016 Feb |
2 |
| 44 |
26590165 | EZH2 Inhibition Blocks Multiple Myeloma Cell Growth through Upregulation of Epithelial Tumor Suppressor Genes. | 2016 Feb |
1 |
| 45 |
27135738 | An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation. | 2016 Jun |
1 |
| 46 |
27226494 | EZH2 is required for mouse oocyte meiotic maturation by interacting with and stabilizing spindle assembly checkpoint protein BubRI. | 2016 Sep 19 |
2 |
| 47 |
27758858 | Enhancer of Zeste Homolog 2 Inhibition Stimulates Bone Formation and Mitigates Bone Loss Caused by Ovariectomy in Skeletally Mature Mice. | 2016 Nov 18 |
2 |
| 48 |
27783950 | Roles of H3K27me2 and H3K27me3 Examined during Fate Specification of Embryonic Stem Cells. | 2016 Oct 25 |
1 |
| 49 |
27897169 | EZH1 and EZH2 promote skeletal growth by repressing inhibitors of chondrocyte proliferation and hypertrophy. | 2016 Nov 29 |
1 |
| 50 |
25043748 | The methyltransferase EZH2 is not required for mammary cancer development, although high EZH2 and low H3K27me3 correlate with poor prognosis of ER-positive breast cancers. | 2015 Oct |
2 |