Sorafenib

fms related receptor tyrosine kinase 3 ; Homo sapiens







202 Article(s)
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1 34459465 Acute myeloid leukemia with cup-like blasts and FLT3-ITD and NPM1 mutations mimics features of acute promyelocytic leukemia: a case of durable remission after sorafenib and low-dose cytarabine. 2022 Jan 1 1
2 35062934 Novel FLT3/AURK multikinase inhibitor is efficacious against sorafenib-refractory and sorafenib-resistant hepatocellular carcinoma. 2022 Jan 21 1
3 35349331 Sorafenib in Combination With Standard Chemotherapy for Children With High Allelic Ratio FLT3/ITD+ Acute Myeloid Leukemia: A Report From the Children's Oncology Group Protocol AAML1031. 2022 Jun 20 1
4 35460465 FLT3-inhibitor therapy for prevention and treatment of relapse after allogeneic hematopoietic cell transplantation. 2022 Apr 23 1
5 35532877 FLT3-targeted treatment for acute myeloid leukemia. 2022 May 9 2
6 35549749 The FLT3 Y842D mutation may be highly sensitive to midostaurin: a case report. 2022 May 2
7 35565314 Target Therapy for Extramedullary Relapse of FLT3-ITD Acute Myeloid Leukemia: Emerging Data from the Field. 2022 Apr 27 1
8 35571528 Diagnosis and Management of Atypical Chronic Myeloid Leukemia with a t(2;13)(q33;q12) Translocation. 2022 1
9 35637252 Clinical outcomes in patients with relapsed/refractory FLT3-mutated acute myeloid leukemia treated with gilteritinib who received prior midostaurin or sorafenib. 2022 May 30 1
10 32753705 Maintenance sorafenib is superior to prophylactic donor lymphocyte infusion at improving the prognosis of acute myeloid leukemia with FMS-like tyrosine kinase 3 internal tandem duplication after allogeneic hematopoietic stem cell transplantation. 2021 Jan 1
11 32852395 Partial Response to Sorafenib in a Child With a Myeloid/Lymphoid Neoplasm, Eosinophilia, and a ZMYM2-FLT3 Fusion. 2021 May 1 2
12 33472354 Maintenance therapy for FLT3-ITD-mutated acute myeloid leukemia. 2021 Mar 1 1
13 33514926 Pre-emptive use of Sorafenib combined with DLI post HSCT in AML FLT3+: a single center experience. 2021 Jun 1
14 33628103 LY3214996 relieves acquired resistance to sorafenib in hepatocellular carcinoma cells. 2021 1
15 33637883 Correction to: Pre-emptive use of Sorafenib combined with DLI post HSCT in AML FLT3+: a single center experience. 2021 Jun 1
16 33667419 Computational model of cardiomyocyte apoptosis identifies mechanisms of tyrosine kinase inhibitor-induced cardiotoxicity. 2021 Jun 1
17 34024909 FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation. 2021 May 24 1
18 34341323 Maintenance therapies in acute myeloid leukemia: the renaissance of an old therapeutic concept. 2021 Nov 1 1
19 34486940 FMS-like tyrosine kinase-3 (FLT3) inhibitors with better binding affinity and ADMET properties than sorafenib and gilteritinib against acute myeloid leukemia: in silico studies. 2021 Sep 6 4
20 34820336 LY294002 Is a Promising Inhibitor to Overcome Sorafenib Resistance in FLT3-ITD Mutant AML Cells by Interfering With PI3K/Akt Signaling Pathway. 2021 3
21 34876631 FLT3-ITD allelic ratio and HLF expression predict FLT3 inhibitor efficacy in adult AML. 2021 Dec 7 1
22 35071015 Hypomethylating Agent-Based Combination Therapies to Treat Post-Hematopoietic Stem Cell Transplant Relapse of Acute Myeloid Leukemia. 2021 1
23 31511612 Fusion driven JMML: a novel CCDC88C-FLT3 fusion responsive to sorafenib identified by RNA sequencing. 2020 Feb 1
24 32022292 Harnessing the immune system after allogeneic stem cell transplant in acute myeloid leukemia. 2020 May 1
25 32332018 High FLT3 Levels May Predict Sorafenib Benefit in Hepatocellular Carcinoma. 2020 Aug 15 6
26 32373219 Targeted sequencing reveals the mutational landscape responsible for sorafenib therapy in advanced hepatocellular carcinoma. 2020 1
27 32673171 Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With FLT3-Internal Tandem Duplication Mutation (SORMAIN). 2020 Sep 10 1
28 32697348 Phase 1 study of combinatorial sorafenib, G-CSF, and plerixafor treatment in relapsed/refractory, FLT3-ITD-mutated acute myelogenous leukemia patients. 2020 Nov 1
29 32791048 Sorafenib maintenance in patients with FLT3-ITD acute myeloid leukaemia undergoing allogeneic haematopoietic stem-cell transplantation: an open-label, multicentre, randomised phase 3 trial. 2020 Sep 2
30 32882995 Novel Multitarget Therapies for Lung Cancer and Respiratory Disease. 2020 Sep 1 1
31 32984009 First Report of Sorafenib in Patients With Acute Myeloid Leukemia Harboring Non-Canonical FLT3 Mutations. 2020 1
32 33255818 Pan-RAF Inhibition Shows Anti-Leukemic Activity in RAS-Mutant Acute Myeloid Leukemia Cells and Potentiates the Effect of Sorafenib in Cells with FLT3 Mutation. 2020 Nov 25 2
33 30270754 FLT3 inhibitors in acute myeloid leukemia: Current and future. 2019 Jan 1
34 30514174 Discontinuation of sorafenib can lead to the emergence of FLT3-ITD-positive acute myeloid leukemia. 2019 Dec 1
35 30537918 Dose-related periorbital edema following sorafenib in a patient with acute myeloid leukemia. 2019 Dec 2
36 30681373 Advancing treatment of acute myeloid leukemia: the future of FLT3 inhibitors. 2019 Mar 1
37 30792203 Sorafenib improves survival of FLT3-mutated acute myeloid leukemia in relapse after allogeneic stem cell transplantation: a report of the EBMT Acute Leukemia Working Party. 2019 Sep 1
38 30898762 Role of CYP3A4 in bone marrow microenvironment-mediated protection of FLT3/ITD AML from tyrosine kinase inhibitors. 2019 Mar 26 2
39 31009704 Sorafenib Therapy Is Associated with Improved Outcomes for FMS-like Tyrosine Kinase 3 Internal Tandem Duplication Acute Myeloid Leukemia Relapsing after Allogeneic Hematopoietic Stem Cell Transplantation. 2019 Aug 1
40 31046582 Renal Cell Carcinoma With Extensive Tumor Thrombus Into the Inferior Vena Cava and Right Atrium in a 70-Year-Old Man. 2019 May-Jun 2
41 31122828 Efficacy and Feasibility of Sorafenib as a Maintenance Agent After Allogeneic Hematopoietic Stem Cell Transplantation for Fms-like Tyrosine Kinase 3 Mutated Acute Myeloid Leukemia: An Update. 2019 Aug 4
42 31203997 Incorporating FLT3 inhibitors in the frontline treatment of FLT3 mutant acute myeloid leukemia. 2019 Jun 3
43 31207705 [Analysis of induction efficacy and prognostic factors in FLT3-ITD positive acute myeloid leukemia in the real world]. 2019 May 14 4
44 31237017 Prognostic significance of baseline FLT3-ITD mutant allele level in acute myeloid leukemia treated with intensive chemotherapy with/without sorafenib. 2019 Sep 2
45 31243041 Availability of FLT3 inhibitors: how do we use them? 2019 Aug 29 1
46 31281512 Melatonin enhances sorafenib-induced cytotoxicity in FLT3-ITD acute myeloid leukemia cells by redox modification. 2019 4
47 31310323 Sorafenib plus intensive chemotherapy improves survival in patients with newly diagnosed, FLT3-internal tandem duplication mutation-positive acute myeloid leukemia. 2019 Nov 1 3
48 31391334 Augmentation of IFN-γ+ CD8+ T cell responses correlates with survival of HCC patients on sorafenib therapy. 2019 Aug 8 1
49 31418362 [Effect of Low-Dose Triptolide and Sorafenib Alone and Their Combination on AML Cell Line MV411 and the Pathway of STAT5]. 2019 Aug 2
50 28876197 The impact of FLT3 mutations on treatment response and survival in Chinese de novo AML patients. 2018 Apr 1