Cysteine

transient receptor potential cation channel subfamily A member 1 ; Homo sapiens







44 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33152265 A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel. 2021 Jan 20 1
2 34189279 Functional evidence of distinct electrophile-induced activation states of the ion channel TRPA1. 2021 Sep 1
3 31866091 Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel. 2020 Mar 4 2
4 32933054 Electrophile-Induced Conformational Switch of the Human TRPA1 Ion Channel Detected by Mass Spectrometry. 2020 Sep 11 1
5 30738091 Identification of molecular targets for toxic action by persulfate, an industrial sulfur compound. 2019 May 1
6 30794546 Multimerization of Homo sapiens TRPA1 ion channel cytoplasmic domains. 2019 1
7 30794923 The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel. 2019 Apr 1
8 30345869 Etomidate and propylene glycol activate nociceptive TRP ion channels. 2018 Jan-Dec 1
9 28769017 TRP channels in oxygen physiology: distinctive functional properties and roles of TRPA1 in O2 sensing. 2017 2
10 28805980 An environmental pollutant, 9,10-phenanthrenequinone, activates human TRPA1 via critical cysteines 621 and 665. 2017 Aug 1
11 29163216 Distinct Mechanism of Cysteine Oxidation-Dependent Activation and Cold Sensitization of Human Transient Receptor Potential Ankyrin 1 Channel by High and Low Oxaliplatin. 2017 5
12 26969190 Sensing of redox status by TRP channels. 2016 Aug 1
13 27241698 The exceptionally high reactivity of Cys 621 is critical for electrophilic activation of the sensory nerve ion channel TRPA1. 2016 Jun 4
14 27356469 Systemic desensitization through TRPA1 channels by capsazepine and mustard oil - a novel strategy against inflammation and pain. 2016 Jun 30 2
15 25897313 The role of flavor and fragrance chemicals in TRPA1 (transient receptor potential cation channel, member A1) activity associated with allergies. 2015 2
16 26064575 Potency of irritation by benzylidenemalononitriles in humans correlates with TRPA1 ion channel activation. 2015 Jan 1
17 26411770 Deciphering Subtype-Selective Modulations in TRPA1 Biosensor Channels. 2015 2
18 24202912 Transnitrosylation directs TRPA1 selectivity in N-nitrosamine activators. 2014 Jan 4
19 24944203 The NADPH oxidase inhibitor diphenyleneiodonium activates the human TRPA1 nociceptor. 2014 Aug 15 1
20 24961969 TRPs as chemosensors (ROS, RNS, RCS, gasotransmitters). 2014 2
21 25041656 Contact sensitizer 2,4-dinitrochlorobenzene is a highly potent human TRPA1 agonist. 2014 Oct 1
22 25302704 Hydrogen sulfide and polysulfides as biological mediators. 2014 Oct 9 1
23 25505619 Nordihydroguaiaretic acid activates hTRPA1 and modulates behavioral responses to noxious cold in mice. 2014 Dec 1
24 23220116 Stimulation of human TRPA1 channels by clinical concentrations of the antirheumatic drug auranofin. 2013 Feb 15 3
25 23396078 Photochemical activation of TRPA1 channels in neurons and animals. 2013 Apr 1
26 23478802 Benzoquinone reveals a cysteine-dependent desensitization mechanism of TRPA1. 2013 May 6
27 24027177 Etodolac activates and desensitizes transient receptor potential ankyrin 1. 2013 Dec 1
28 21518269 Sustained TRPA1 activation in vivo. 2012 Feb 1
29 22207754 Identification of in vivo disulfide conformation of TRPA1 ion channel. 2012 Feb 24 10
30 22222967 Primary alcohols activate human TRPA1 channel in a carbon chain length-dependent manner. 2012 Apr 1
31 22740698 Methylglyoxal activates nociceptors through transient receptor potential channel A1 (TRPA1): a possible mechanism of metabolic neuropathies. 2012 Aug 17 1
32 22869685 Isothiocyanates from Wasabia japonica activate transient receptor potential ankyrin 1 channel. 2012 Nov 2
33 23001121 The transient receptor potential channel TRPA1: from gene to pathophysiology. 2012 Nov 1
34 21078588 Irritating channels: the case of TRPA1. 2011 Apr 1 1
35 21094256 TRPA1 is activated by direct addition of cysteine residues to the N-hydroxysuccinyl esters of acrylic and cinnamic acids. 2011 Jan 4
36 21855605 Curcumin ((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) activates and desensitizes the nociceptor ion channel TRPA1. 2011 Oct 10 2
37 21861907 Activation of TRPA1 by membrane permeable local anesthetics. 2011 Aug 23 2
38 19888597 Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs. 2010 Mar 1
39 21112285 The Met268Pro mutation of mouse TRPA1 changes the effect of caffeine from activation to suppression. 2010 Dec 1 1
40 18463259 Molecular determinants of species-specific activation or blockade of TRPA1 channels. 2008 May 7 1
41 18501939 Tear gasses CN, CR, and CS are potent activators of the human TRPA1 receptor. 2008 Sep 1 1
42 18769139 Molecular characterization of TRPA1 channel activation by cysteine-reactive inflammatory mediators. 2008 Jul-Aug 5
43 18815250 Identification of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels. 2008 Sep 24 1
44 17164327 TRP channel activation by reversible covalent modification. 2006 Dec 19 1