allyl isothiocyanate

transient receptor potential cation channel subfamily A member 1 ; Homo sapiens







76 Article(s)
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1 34973335 Selective activation of TRPA1 ion channels by nitrobenzene skin sensitizers DNFB and DNCB. 2022 Feb 4
2 35163843 Functional Transient Receptor Potential Ankyrin 1 and Vanilloid 1 Ion Channels Are Overexpressed in Human Oral Squamous Cell Carcinoma. 2022 Feb 8 3
3 32415670 Development of AITC-induced dermal blood flow as a translational in vivo biomarker of TRPA1 activity in human and rodent skin. 2021 Jan 3
4 33458442 Allyl isothiocyanate (AITC) activates nonselective cation currents in human cardiac fibroblasts: possible involvement of TRPA1. 2021 Jan 3
5 33479347 Functional expression of the transient receptor potential ankyrin type 1 channel in pancreatic adenocarcinoma cells. 2021 Jan 21 2
6 33579280 AITC inhibits fibroblast-myofibroblast transition via TRPA1-independent MAPK and NRF2/HO-1 pathways and reverses corticosteroids insensitivity in human lung fibroblasts. 2021 Feb 12 3
7 34058071 Translational and pharmacokinetic-pharmacodynamic application for the clinical development of GDC-0334, a novel TRPA1 inhibitor. 2021 Sep 1
8 34912298 Intersections in Neuropsychiatric and Metabolic Disorders: Possible Role of TRPA1 Channels. 2021 1
9 32050145 An inflammatory stimulus sensitizes TRPA1 channel to increase cytokine release in human lung fibroblasts. 2020 May 6
10 32233794 Transient receptor potential ankyrin-1 causes rapid bronchodilation via nonepithelial PGE2. 2020 May 1 1
11 32402637 Regulation of vascular tone by transient receptor potential ankyrin 1 channels. 2020 1
12 33117171 Transgenic Chlamydomonas Expressing Human Transient Receptor Potential Ankyrin 1 (TRPA1) Channels to Assess the Effect of Agonists and Antagonists. 2020 5
13 33320598 Induction of Irritation and Inflammation in a 3D Innervated Tissue Model of the Human Cornea. 2020 Dec 14 2
14 30679204 trans-Anethole of Fennel Oil is a Selective and Nonelectrophilic Agonist of the TRPA1 Ion Channel. 2019 Apr 2
15 31170994 Heterogeneity of cough hypersensitivity mediated by TRPV1 and TRPA1 in patients with chronic refractory cough. 2019 Jun 6 4
16 31216970 TRPA1 Channel as a Regulator of Neurogenic Inflammation and Pain: Structure, Function, Role in Pathophysiology, and Therapeutic Potential of Ligands. 2019 Feb 1
17 31488616 Transient receptor potential ankyrin1 channel is endogenously expressed in T cells and is involved in immune functions. 2019 Sep 30 4
18 31796582 TRPA1 modulation by piperidine carboxamides suggests an evolutionarily conserved binding site and gating mechanism. 2019 Dec 17 2
19 31805147 Pharmacological or genetic targeting of Transient Receptor Potential (TRP) channels can disrupt the planarian escape response. 2019 4
20 27759880 The peptide Phα1β, from spider venom, acts as a TRPA1 channel antagonist with antinociceptive effects in mice. 2017 Jan 4
21 28515697 TRPA1 Channels Modify TRPV1-Mediated Current Responses in Dorsal Root Ganglion Neurons. 2017 3
22 28571526 TRPA1 Channels Mediate Human Gingival Fibroblast Response to Phenytoin. 2017 Jul 1
23 28576617 Synthesis of resveratrol derivatives as new analgesic drugs through desensitization of the TRPA1 receptor. 2017 Jul 15 2
24 28614189 Dose-response study of topical allyl isothiocyanate (mustard oil) as a human surrogate model of pain, hyperalgesia, and neurogenic inflammation. 2017 Sep 2
25 28629997 Membrane translocation of transient receptor potential ankyrin 1 induced by inflammatory cytokines in lung cancer cells. 2017 Aug 26 1
26 26634370 Cold stress increases reactive oxygen species formation via TRPA1 activation in A549 cells. 2016 Mar 1
27 26928772 The TRPA1 Activator Allyl Isothiocyanate (AITC) Contracts Human Jejunal Muscle: Pharmacological Analysis. 2016 Sep 3
28 27345869 N-terminal tetrapeptide T/SPLH motifs contribute to multimodal activation of human TRPA1 channel. 2016 Jun 27 1
29 27799370 Intracellular TRPA1 mediates Ca2+ release from lysosomes in dorsal root ganglion neurons. 2016 Nov 7 2
30 27899696 Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats. 2016 4
31 25642661 Tramadol and its metabolite m1 selectively suppress transient receptor potential ankyrin 1 activity, but not transient receptor potential vanilloid 1 activity. 2015 Apr 1
32 25978436 Five hTRPA1 Agonists Found in Indigenous Korean Mint, Agastache rugosa. 2015 1
33 26171233 Propofol restores TRPV1 sensitivity via a TRPA1-, nitric oxide synthase-dependent activation of PKCε. 2015 Aug 1
34 26351757 Chemical sensing properties of Takifugu TRPA1. 2015 Oct 21 1
35 24815021 Enhanced production of nitric oxide in A549 cells through activation of TRPA1 ion channel by cold stress. 2014 Aug 31 1
36 24893987 Mouse monoclonal antibodies to transient receptor potential ankyrin 1 act as antagonists of multiple modes of channel activation. 2014 Aug 2
37 25062738 TRPA1 and TRPV4 activation in human odontoblasts stimulates ATP release. 2014 Sep 1
38 25172898 Effects of methylglyoxal on human cardiac fibroblast: roles of transient receptor potential ankyrin 1 (TRPA1) channels. 2014 Nov 1 1
39 23219522 Stimulation of the chemosensory TRPA1 cation channel by volatile toxic substances promotes cell survival of small cell lung cancer cells. 2013 Feb 1 3
40 23413875 Modulation of TRP channels by resveratrol and other stilbenoids. 2013 Feb 15 2
41 23477783 Novel therapeutic strategy to prevent chemotherapy-induced persistent sensory neuropathy by TRPA1 blockade. 2013 May 15 1
42 23994502 Functional expression of the transient receptor potential channel TRPA1, a sensor for toxic lung inhalants, in pulmonary epithelial cells. 2013 Dec 5 2
43 24027177 Etodolac activates and desensitizes transient receptor potential ankyrin 1. 2013 Dec 1
44 23192000 1,8-cineole, a TRPM8 agonist, is a novel natural antagonist of human TRPA1. 2012 Nov 29 1
45 20135626 The cannabinoid WIN 55,212-2-mediated protection of dentate gyrus granule cells is driven by CB1 receptors and modulated by TRPA1 and Cav 2.2 channels. 2011 May 2
46 21051219 A cell-based impedance assay for monitoring transient receptor potential (TRP) ion channel activity. 2011 Jan 15 2
47 21195050 The pore properties of human nociceptor channel TRPA1 evaluated in single channel recordings. 2011 Apr 2
48 21316356 Transient receptor potential (TRP) A1 activated currents in TRPV1 and cholecystokinin-sensitive cranial visceral afferent neurons. 2011 Apr 6 2
49 21558163 TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity. 2011 Jul 15 4
50 21619614 Inhibition of TRPA1 channel activity in sensory neurons by the glial cell line-derived neurotrophic factor family member, artemin. 2011 May 27 2