| 1 |
34020817 | A non-affinity purification process for GMP production of prefusion-closed HIV-1 envelope trimers from clades A and C for clinical evaluation. | 2021 Jun 8 |
1 |
| 2 |
30429345 | Conformational Differences between Functional Human Immunodeficiency Virus Envelope Glycoprotein Trimers and Stabilized Soluble Trimers. | 2019 Feb 1 |
1 |
| 3 |
29470989 | Redox exchange of the disulfides of human two-domain CD4 regulates the conformational dynamics of each domain, providing insight into its mechanisms of control. | 2018 Mar 4 |
3 |
| 4 |
26860867 | New Approach for Inhibition of HIV Entry: Modifying CD4 Binding Sites by Thiolated Pyrimidine Derivatives. | 2016 Jul |
1 |
| 5 |
27009680 | Human CD4 Metastability Is a Function of the Allosteric Disulfide Bond in Domain 2. | 2016 Apr 19 |
9 |
| 6 |
27041594 | Paring Down HIV Env: Design and Crystal Structure of a Stabilized Inner Domain of HIV-1 gp120 Displaying a Major ADCC Target of the A32 Region. | 2016 May 3 |
1 |
| 7 |
27233453 | Thioredoxin (Trx1) regulates CD4 membrane domain localization and is required for efficient CD4-dependent HIV-1 entry. | 2016 Sep |
1 |
| 8 |
25944298 | Conformational instability governed by disulfide bonds partitions the dominant from subdominant helper T-cell responses specific for HIV-1 envelope glycoprotein gp120. | 2015 Jun 9 |
1 |
| 9 |
26690492 | Discovery of a Natural Defense Against HIV With Therapeutic Potential. | 2015 Oct-Dec |
1 |
| 10 |
26719252 | Structure-Guided Redesign Increases the Propensity of HIV Env To Generate Highly Stable Soluble Trimers. | 2015 Dec 30 |
2 |
| 11 |
24257748 | CD4 and BST-2/tetherin proteins retro-translocate from endoplasmic reticulum to cytosol as partially folded and multimeric molecules. | 2014 Jan 3 |
2 |
| 12 |
25299596 | Probing the effect of force on HIV-1 receptor CD4. | 2014 Oct 28 |
2 |
| 13 |
24146829 | Stabilizing exposure of conserved epitopes by structure guided insertion of disulfide bond in HIV-1 envelope glycoprotein. | 2013 |
4 |
| 14 |
22291921 | Elicitation of neutralizing antibodies directed against CD4-induced epitope(s) using a CD4 mimetic cross-linked to a HIV-1 envelope glycoprotein. | 2012 |
1 |
| 15 |
20538591 | Stabilization of HIV-1 gp120-CD4 receptor complex through targeted interchain disulfide exchange. | 2010 Aug 13 |
11 |
| 16 |
20943653 | Disulfide bond that constrains the HIV-1 gp120 V3 domain is cleaved by thioredoxin. | 2010 Dec 17 |
6 |
| 17 |
20974843 | Reduced monomeric CD4 is the preferred receptor for HIV. | 2010 Dec 24 |
1 |
| 18 |
19038358 | Human glutaredoxin-1 catalyzes the reduction of HIV-1 gp120 and CD4 disulfides and its inhibition reduces HIV-1 replication. | 2009 Jun |
3 |
| 19 |
19018669 | High-affinity binding of southern African HIV type 1 subtype C envelope protein, gp120, to the CCR5 coreceptor. | 2008 Dec |
1 |
| 20 |
16480776 | Molecular cloning and sequencing of the cDNA encoding the bat CD4. | 2006 Jun 15 |
1 |
| 21 |
16507315 | Role of protein disulfide isomerase and other thiol-reactive proteins in HIV-1 envelope protein-mediated fusion. | 2006 Jul 5 |
3 |
| 22 |
16519733 | Marked differences in the structures and protein associations of lymphocyte and monocyte CD4: resolution of a novel CD4 isoform. | 2006 Apr |
2 |
| 23 |
16633351 | Site-specific PEGylation of native disulfide bonds in therapeutic proteins. | 2006 Jun |
1 |
| 24 |
16709847 | Evidence for a domain-swapped CD4 dimer as the coreceptor for binding to class II MHC. | 2006 Jun 1 |
6 |
| 25 |
15322779 | Cloning, expression, and characterization of fugu CD4, the first ectothermic animal CD4. | 2004 Aug |
1 |
| 26 |
12218052 | Protein-disulfide isomerase-mediated reduction of two disulfide bonds of HIV envelope glycoprotein 120 occurs post-CXCR4 binding and is required for fusion. | 2003 Jan 31 |
1 |
| 27 |
12897445 | Disulfide exchange in CD4. | 2003 |
1 |
| 28 |
12089508 | Disulfide exchange in domain 2 of CD4 is required for entry of HIV-1. | 2002 Aug |
2 |
| 29 |
12218051 | Inhibitors of protein-disulfide isomerase prevent cleavage of disulfide bonds in receptor-bound glycoprotein 120 and prevent HIV-1 entry. | 2002 Dec 27 |
4 |
| 30 |
8707860 | Intracellular location of cysteine transport activity correlates with productive processing of antigen disulfide. | 1996 Aug |
1 |
| 31 |
8554907 | Alanine substitution of two arginines in amino terminus of V3 of SIV disrupts CD4 binding whereas a similar replacement of two amino acids, lysine and arginine, in the carboxyl half of V3 prevents binding of a neutralizing monoclonal antibody. | 1995 Sep |
1 |
| 32 |
1985197 | Identification of the principal neutralizing determinant of human immunodeficiency virus type 1 as a fusion domain. | 1991 Jan |
1 |
| 33 |
2494662 | Molecular heterogeneity of gamma delta T-cell antigen receptors expressed by CD4- CD8- T-cell clones from normal donors: both disulfide- and non-disulfide-linked receptors are delta TCS1+. | 1989 Apr |
1 |
| 34 |
2513572 | CD4 and CD8 molecules can physically associate with the same T-cell receptor. | 1989 Dec |
1 |
| 35 |
2558637 | Cystein 402 of HIV gp 120 is essential for CD4-binding and resistance of gp 120 to intracellular degradation. | 1989 |
1 |
| 36 |
2453925 | Location and chemical synthesis of a binding site for HIV-1 on the CD4 protein. | 1988 Jun 3 |
1 |
| 37 |
3104900 | Peptide and nucleotide sequences of rat CD4 (W3/25) antigen: evidence for derivation from a structure with four immunoglobulin-related domains. | 1987 Mar |
1 |