AZD 1480

Janus kinase 2 ; Mus musculus







8 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 31467427 JAK2/STAT1-mediated HMGB1 translocation increases inflammation and cell death in a ventilator-induced lung injury model. 2019 Dec 2
2 30007232 Erythropoietin alleviates hyperglycaemia-associated inflammation by regulating macrophage polarization via the JAK2/STAT3 signalling pathway. 2018 Sep 1
3 27976373 Tumour-associated macrophage-mediated survival of myeloma cells through STAT3 activation. 2017 Mar 1
4 28292965 Repurposed JAK1/JAK2 Inhibitor Reverses Established Autoimmune Insulitis in NOD Mice. 2017 Jun 1
5 24359159 Discovery of 1-methyl-1H-imidazole derivatives as potent Jak2 inhibitors. 2014 Jan 9 1
6 23942095 Pharmacologic inhibition of Jak2-Stat5 signaling By Jak2 inhibitor AZD1480 potently suppresses growth of both primary and castrate-resistant prostate cancer. 2013 Oct 15 6
7 21926964 Kinase domain mutations confer resistance to novel inhibitors targeting JAK2V617F in myeloproliferative neoplasms. 2012 Apr 1
8 21164517 The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival. 2011 Mar 1