| 1 |
34942093 | Longer CAG repeat length is associated with shorter survival after disease onset in Huntington disease. | 2022 Jan 6 |
1 |
| 2 |
35108063 | Development of a ligand for in vivo imaging of mutant huntingtin in Huntington's disease. | 2022 Feb 2 |
3 |
| 3 |
35241644 | An orally available, brain penetrant, small molecule lowers huntingtin levels by enhancing pseudoexon inclusion. | 2022 Mar 3 |
2 |
| 4 |
35395060 | Development of mAb-based polyglutamine-dependent and polyglutamine length-independent huntingtin quantification assays with cross-site validation. | 2022 |
2 |
| 5 |
35608753 | CRISPR-Based Genome-Editing Tools for Huntington's Disease Research and Therapy. | 2022 May 24 |
2 |
| 6 |
35615642 | Current and Possible Future Therapeutic Options for Huntington's Disease. | 2022 |
2 |
| 7 |
32235053 | The phasor FLIM method reveals a link between a change in energy metabolism and mHtt protein spread in healthy Mammalian cells when co-cultured with Huntington diseased cells. | 2021 Jan 11 |
2 |
| 8 |
33517535 | Developmental malformations in Huntington disease: neuropathologic evidence of focal neuronal migration defects in a subset of adult brains. | 2021 Mar |
1 |
| 9 |
33567536 | A Novel Triplet-Primed PCR Assay to Detect the Full Range of Trinucleotide CAG Repeats in the Huntingtin Gene (HTT). | 2021 Feb 8 |
2 |
| 10 |
33576024 | False-negative tests in Huntington's disease: A new variant within primer hybridization site. | 2021 Jun |
2 |
| 11 |
33586075 | Huntington's Disease: New Frontiers in Therapeutics. | 2021 Feb 14 |
1 |
| 12 |
33606279 | An imaging mass spectrometry atlas of lipids in the human neurologically normal and Huntington's disease caudate nucleus. | 2021 Jun |
1 |
| 13 |
34038804 | Epigenetic regulation in Huntington's disease. | 2021 Sep |
2 |
| 14 |
34098113 | Gene targeting techniques for Huntington's disease. | 2021 Sep |
1 |
| 15 |
34180418 | Association Analysis of Chromosome X to Identify Genetic Modifiers of Huntington's Disease. | 2021 |
2 |
| 16 |
34206228 | Cell Reprogramming to Model Huntington's Disease: A Comprehensive Review. | 2021 Jun 22 |
1 |
| 17 |
34211373 | Huntingtin and the Synapse. | 2021 |
3 |
| 18 |
34266596 | Hypothalamic pathology in Huntington disease. | 2021 |
1 |
| 19 |
34423068 | Patients With Extreme Early Onset Juvenile Huntington Disease Can Have Delays in Diagnosis: A Case Report and Literature Review. | 2021 Jan-Dec |
1 |
| 20 |
34504195 | Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidates. | 2021 Sep 9 |
4 |
| 21 |
34520257 | Oligonucleotides Targeting DNA Repeats Downregulate Huntingtin Gene Expression in Huntington's Patient-Derived Neural Model System. | 2021 Dec |
4 |
| 22 |
34786953 | Sporadic Huntington's disease in the Philippines: a case report. | 2021 Dec |
1 |
| 23 |
34830381 | Non-Cell Autonomous and Epigenetic Mechanisms of Huntington's Disease. | 2021 Nov 19 |
2 |
| 24 |
34831058 | The Cytotoxicity and Clearance of Mutant Huntingtin and Other Misfolded Proteins. | 2021 Oct 21 |
1 |
| 25 |
34884576 | Myelinosome Organelles in the Retina of R6/1 Huntington Disease (HD) Mice: Ubiquitous Distribution and Possible Role in Disease Spreading. | 2021 Nov 25 |
2 |
| 26 |
34911927 | Small molecule splicing modifiers with systemic HTT-lowering activity. | 2021 Dec 15 |
2 |
| 27 |
31223078 | Reviewing Biochemical Implications of Normal and Mutated Huntingtin in Huntington's Disease. | 2020 |
1 |
| 28 |
31899071 | Huntington's Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy. | 2020 Mar 4 |
1 |
| 29 |
32279715 | Medical, Surgical, and Genetic Treatment of Huntington Disease. | 2020 May |
1 |
| 30 |
32407769 | Inhibiting cellular uptake of mutant huntingtin using a monoclonal antibody: Implications for the treatment of Huntington's disease. | 2020 Jul |
2 |
| 31 |
32555394 | High frequency of intermediary alleles in the HTT gene in Northern Sweden - The Swedish Huntingtin Alleles and Phenotype (SHAPE) study. | 2020 Jun 17 |
4 |
| 32 |
32566927 | Altered cerebrovascular response to acute exercise in patients with Huntington's disease. | 2020 |
1 |
| 33 |
32657893 | Therapeutic strategies for Huntington's disease. | 2020 Aug |
1 |
| 34 |
32979507 | Inconsistencies in histone acetylation patterns among different HD model systems and HD post-mortem brains. | 2020 Dec |
1 |
| 35 |
33049985 | Investigating the Transition of Pre-Symptomatic to Symptomatic Huntington's Disease Status Based on Omics Data. | 2020 Oct 8 |
2 |
| 36 |
33329316 | RNA Sequencing of Human Peripheral Blood Cells Indicates Upregulation of Immune-Related Genes in Huntington's Disease. | 2020 |
1 |
| 37 |
30419368 | Huntington disease: A quarter century of progress since the gene discovery. | 2019 Jan 15 |
2 |
| 38 |
30573872 | Spectrum of tau pathologies in Huntington's disease. | 2019 Jul |
1 |
| 39 |
31103960 | Clinical phenotype in carriers of intermediate alleles in the huntingtin gene. | 2019 Jul 15 |
1 |
| 40 |
31296921 | Full sequence of mutant huntingtin 3'-untranslated region and modulation of its gene regulatory activity by endogenous microRNA. | 2019 Oct |
2 |
| 41 |
31358058 | A soluble truncated tau species related to cognitive dysfunction and caspase-2 is elevated in the brain of Huntington's disease patients. | 2019 Jul 30 |
3 |
| 42 |
28817209 | Huntington's disease: a clinical review. | 2018 Jan |
1 |
| 43 |
29134321 | Co-occurrence of mixed proteinopathies in late-stage Huntington's disease. | 2018 Feb |
2 |
| 44 |
29212816 | Complete suppression of Htt fibrilization and disaggregation of Htt fibrils by a trimeric chaperone complex. | 2018 Jan 17 |
2 |
| 45 |
29218782 | Therapy development in Huntington disease: From current strategies to emerging opportunities. | 2018 Apr |
2 |
| 46 |
29427096 | Clinical Features of Huntington's Disease. | 2018 |
1 |
| 47 |
29440125 | Small interfering RNAs based on huntingtin trinucleotide repeats are highly toxic to cancer cells. | 2018 Mar |
1 |
| 48 |
29802276 | A human huntingtin SNP alters post-translational modification and pathogenic proteolysis of the protein causing Huntington disease. | 2018 May 25 |
2 |
| 49 |
29889077 | Cancer: From Wild-Type to Mutant Huntingtin. | 2018 |
2 |
| 50 |
29898922 | Epigenetic alterations mediate iPSC-induced normalization of DNA repair gene expression and TNR stability in Huntington's disease cells. | 2018 Jul 6 |
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