Calcium

purinergic receptor P2X 7 ; Homo sapiens







75 Article(s)
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1 34622987 Tyrosine 288 in the extracellular domain of the human P2X7 receptor is critical for receptor function revealed by structural modeling and site-directed mutagenesis. 2022 Mar 2
2 35222364 P2X7 Receptor Triggers Lysosomal Leakage Through Calcium Mobilization in a Mechanism Dependent on Pannexin-1 Hemichannels. 2022 2
3 34606909 Intracellular calcium and inflammatory markers, mediated by purinergic stimulation, are differentially regulated in monocytes of patients with major depressive disorder. 2021 Nov 20 1
4 34827446 Challenges in Treating Charcot-Marie-Tooth Disease and Related Neuropathies: Current Management and Future Perspectives. 2021 Oct 29 1
5 32004973 Effect of P2X7 receptor on tumorigenesis and its pharmacological properties. 2020 May 1
6 33255431 Polarized Cytokine Release Triggered by P2X7 Receptor from Retinal Pigmented Epithelial Cells Dependent on Calcium Influx. 2020 Nov 24 1
7 30652649 Purinergic P2X7 Receptor: A Cation Channel Sensitive to Tumor Microenvironment. 2019 2
8 31009002 Real-time Live-cell Flow Cytometry to Investigate Calcium Influx, Pore Formation, and Phagocytosis by P2X7 Receptors in Adult Neural Progenitor Cells. 2019 Apr 3 1
9 31279855 Metabolic reprogramming in memory CD4 T cell responses of old adults. 2019 Oct 1
10 31727237 Structure, function and techniques of investigation of the P2X7 receptor (P2X7R) in mammalian cells. 2019 1
11 31736956 Toll-Like Receptor-Mediated Activation of CD39 Internalization in BMDCs Leads to Extracellular ATP Accumulation and Facilitates P2X7 Receptor Activation. 2019 1
12 31878359 Polyhexamethylene Guanidine Phosphate Damages Tight Junctions and the F-Actin Architecture by Activating Calpain-1 via the P2RX7/Ca2+ Signaling Pathway. 2019 Dec 24 2
13 29290027 N-terminal tagging of human P2X7 receptor disturbs calcium influx and dye uptake. 2018 Mar 1
14 29937766 Human P2Y11 Expression Level Affects Human P2X7 Receptor-Mediated Cell Death. 2018 1
15 30081297 Calcimycin induced IL-12 production inhibits intracellular mycobacterial growth by enhancing autophagy. 2018 Nov 1
16 27840225 A calcium-sensitive feed-forward loop regulating the expression of the ATP-gated purinergic P2X7 receptor via specificity protein 1 and microRNA-22. 2017 Feb 2
17 27856358 P2X7Rs are involved in cell death, growth and cellular signaling in primary human osteoblasts. 2017 Feb 2
18 28250280 Species Difference in Sensitivity of Human and Mouse P2X7 Receptors to Inhibitory Effects of Divalent Metal Cations. 2017 1
19 28516276 P2X7 receptor-pannexin 1 interaction mediates extracellular alpha-synuclein-induced ATP release in neuroblastoma SH-SY5Y cells. 2017 Sep 1
20 28672157 The P2X7 receptor is an upstream regulator of dynamic blebbing and a pluripotency marker in human embryonic stem cells. 2017 Aug 1
21 25704409 Brilliant blue FCF is a nontoxic dye for saphenous vein graft marking that abrogates response to injury. 2016 Jul 1
22 25998275 Purinergic signaling in retinal degeneration and regeneration. 2016 May 1
23 26671983 Increased Expression and Cellular Localization of P2X7R in Cortical Lesions of Patients With Focal Cortical Dysplasia. 2016 Jan 2
24 26683661 Purinoreceptor P2X7 Regulation of Ca(2+) Mobilization and Cytoskeletal Rearrangement Is Required for Corneal Reepithelialization after Injury. 2016 Feb 2
25 26910735 P2X7 receptors induce degranulation in human mast cells. 2016 Jun 4
26 26986975 Co-Expression of Wild-Type P2X7R with Gln460Arg Variant Alters Receptor Function. 2016 2
27 27453058 Down-regulation of purinergic P2X7 receptor expression and intracellular calcium dysregulation in peripheral blood mononuclear cells of patients with amyotrophic lateral sclerosis. 2016 Sep 6 1
28 28139817 Alzheimer's amyloid-β peptide disturbs P2X7 receptor-mediated circadian oscillations of intracellular calcium. 2016 1
29 25096398 ATP signaling in brain: release, excitotoxicity and potential therapeutic targets. 2015 Jan 1
30 26064953 The Impact of Vitamin D3 Supplementation on Mechanisms of Cell Calcium Signaling in Chronic Kidney Disease. 2015 1
31 26399685 Epigenetic alteration of the purinergic type 7 receptor in salivary epithelial cells. 2015 Oct 30 1
32 26512962 K(+) regulates Ca(2+) to drive inflammasome signaling: dynamic visualization of ion flux in live cells. 2015 Oct 29 2
33 26778965 In vivo Calcium Imaging of Evoked Calcium Waves in the Embryonic Cortex. 2015 1
34 24671093 Probenecid blocks human P2X7 receptor-induced dye uptake via a pannexin-1 independent mechanism. 2014 1
35 24839011 Mechanosensitive release of adenosine 5'-triphosphate through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head astrocytes: a mechanism for purinergic involvement in chronic strain. 2014 Sep 1
36 25306296 Cathelicidin peptide LL-37 increases UVB-triggered inflammasome activation: possible implications for rosacea. 2014 Dec 1
37 22566162 Glucose transporter 2 expression is down regulated following P2X7 activation in enterocytes. 2013 Jan 1
38 23711511 Oxidative stress induced by P2X7 receptor stimulation in murine macrophages is mediated by c-Src/Pyk2 and ERK1/2. 2013 Oct 1
39 23815895 [Dual over-expression of P2X7 receptor and intracellular domain of Notch1 in leukemia cells]. 2013 Jun 1
40 21860249 Purinergic P2X7 receptors participate in disturbed intracellular calcium homeostasis in peripheral blood mononuclear cells of patients with chronic kidney disease. 2012 3
41 22473129 P2X7 receptor-mediated calcium dynamics in HEK293 cells: experimental characterization and modelling approach. 2012 1
42 23067162 [Chronic kidney disease and cellular calcium homeostasis]. 2012 Jul-Aug 2
43 21298493 Transcriptional control mechanisms associated with the nucleotide receptor P2X7, a critical regulator of immunologic, osteogenic, and neurologic functions. 2011 May 1
44 21502139 ATP release due to Thy-1-integrin binding induces P2X7-mediated calcium entry required for focal adhesion formation. 2011 May 1 3
45 21906809 Gain-of-function of P2X7 receptor gene variants in multiple sclerosis. 2011 Nov 1
46 21911484 Calcium-dependent block of P2X7 receptor channel function is allosteric. 2011 Oct 1
47 21925514 Glibenclamide reduces proinflammatory cytokines in an ex vivo model of human endotoxinaemia under hypoxaemic conditions. 2011 Nov 7 1
48 18414844 Inhibition of P2X(7) receptors by divalent cations: old action and new insight. 2009 Mar 1
49 18568426 Selective P2X(7) receptor antagonists for chronic inflammation and pain. 2009 Mar 1
50 18602931 [3H]A-804598 ([3H]2-cyano-1-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine) is a novel, potent, and selective antagonist radioligand for P2X7 receptors. 2009 Jan 1