Lysine

lysine demethylase 6B ; Homo sapiens







53 Article(s)
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1 35239138 Emerging roles of JMJD3 in cancer. 2022 Jul 2
2 35278430 Downregulation of the endothelial histone demethylase JMJD3 is associated with neointimal hyperplasia of arteriovenous fistulas in kidney failure. 2022 May 2
3 33359755 Suppression of canonical TGF-β signaling enables GATA4 to interact with H3K27me3 demethylase JMJD3 to promote cardiomyogenesis. 2021 Apr 1
4 33450416 The KDM6B mutation: Phenotype and clinical characteristics-Report of a case. 2021 Jan 12 2
5 33789369 [Role of histone demethylase KDM6B in HBx-mediated podocyte-macrophage transdifferentiation]. 2021 Mar 30 4
6 34113620 PRMT5 Is Involved in Spermatogonial Stem Cells Maintenance by Regulating Plzf Expression via Modulation of Lysine Histone Modifications. 2021 1
7 34217316 JMJD3: a critical epigenetic regulator in stem cell fate. 2021 Jul 3 2
8 32817139 Lysine Demethylase KDM6A in Differentiation, Development, and Cancer. 2020 Sep 28 2
9 32855205 Inhibition of Histone H3K27 Demethylases Inactivates Brachyury (TBXT) and Promotes Chordoma Cell Death. 2020 Oct 15 2
10 30631055 Histone demethylase KDM6B has an anti-tumorigenic function in neuroblastoma by promoting differentiation. 2019 Jan 4 3
11 30633952 The histone H3 Lys 27 demethylase KDM6B promotes migration and invasion of glioma cells partly by regulating the expression of SNAI1. 2019 Mar 2
12 30651137 Elevated H3K27me3 levels sensitize osteosarcoma to cisplatin. 2019 Jan 16 1
13 30793225 Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Ameliorates the Inflammatory Response in Periodontal Disease. 2019 Aug 2
14 30896884 Targeting P16INK4A in uterine serous carcinoma through inhibition of histone demethylation. 2019 May 1
15 30996803 Identification of the 2-Benzoxazol-2-yl-phenol Scaffold as New Hit for JMJD3 Inhibition. 2019 Apr 11 1
16 31124279 Genetic variants in the KDM6B gene are associated with neurodevelopmental delays and dysmorphic features. 2019 Jul 2
17 28894299 DHEA inhibits acute microglia-mediated inflammation through activation of the TrkA-Akt1/2-CREB-Jmjd3 pathway. 2018 Jun 1
18 29220567 Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity. 2018 Feb 6 2
19 29377540 MicroRNA-99a is a novel regulator of KDM6B-mediated osteogenic differentiation of BMSCs. 2018 Apr 1
20 29594337 Therapeutic potential of GSK-J4, a histone demethylase KDM6B/JMJD3 inhibitor, for acute myeloid leukemia. 2018 Jun 1
21 29753027 JMJD3 inhibition protects against isoproterenol-induced cardiac hypertrophy by suppressing β-MHC expression. 2018 Dec 5 2
22 29859500 Jumonji domain-containing protein 3 regulates the early inflammatory response epigenetically in human periodontal ligament cells. 2018 Sep 3
23 29961803 Human histone demethylase KDM6B can catalyse sequential oxidations. 2018 Jul 12 3
24 27983522 Different expression patterns of histone H3K27 demethylases in renal cell carcinoma and bladder cancer. 2017 1
25 28430662 Histone demethylase JMJD3 regulates CD11a expression through changes in histone H3K27 tri-methylation levels in CD4+ T cells of patients with systemic lupus erythematosus. 2017 Jul 25 1
26 28487543 KDM6B modulates MAPK pathway mediating multiple myeloma cell growth and survival. 2017 Dec 2
27 28509866 HDAC8 Prevents Anthrax Lethal Toxin-induced Cell Cycle Arrest through Silencing PTEN in Human Monocytic THP-1 Cells. 2017 May 16 1
28 26416711 The Prognostic Significance of Histone Lysine Demethylase JMJD3/KDM6B in Colorectal Cancer. 2016 Feb 2
29 26567139 PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer. 2016 Jan 15 1
30 25520177 Regulation of histone demethylase KDM6B by hypoxia-inducible factor-2α. 2015 Feb 2
31 25652587 The histone demethylase jumonji coordinates cellular senescence including secretion of neural stem cell-attracting cytokines. 2015 Apr 2
32 25998860 The histone methyltransferase EZH2 promotes mammary stem and luminal progenitor cell expansion, metastasis and inhibits estrogen receptor-positive cellular differentiation in a model of basal breast cancer. 2015 Jul 1
33 26303949 KDM6B Elicits Cell Apoptosis by Promoting Nuclear Translocation of FOXO1 in Non-Small Cell Lung Cancer. 2015 1
34 24726732 MIR146A inhibits JMJD3 expression and osteogenic differentiation in human mesenchymal stem cells. 2014 May 2 2
35 24798337 Human UTY(KDM6C) is a male-specific Nϵ-methyl lysyl demethylase. 2014 Jun 27 2
36 24947179 Loss of histone demethylase KDM6B enhances aggressiveness of pancreatic cancer through downregulation of C/EBPα. 2014 Nov 1
37 25132549 Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia. 2014 Oct 23 1
38 25176653 Activation of neuronal gene expression by the JMJD3 demethylase is required for postnatal and adult brain neurogenesis. 2014 Sep 11 1
39 22986503 A new horizon for epigenetic medicine? 2013 Mar 1
40 23671187 EED and KDM6B coordinate the first mammalian cell lineage commitment to ensure embryo implantation. 2013 Jul 1
41 23711388 Proteomic changes induced by histone demethylase JMJD3 in TNF alpha-treated human monocytic (THP-1) cells. 2013 Nov 1
42 23748155 Epigenetic induction of the Ink4a/Arf locus prevents Schwann cell overproliferation during nerve regeneration and after tumorigenic challenge. 2013 Jul 1
43 24106268 Histone demethylase Jmjd3 regulates osteoblast differentiation via transcription factors Runx2 and osterix. 2013 Nov 22 2
44 22252741 Gene networking and inflammatory pathway analysis in a JMJD3 knockdown human monocytic cell line. 2012 Apr 2
45 22713873 The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation. 2012 Jun 15 1
46 23103168 The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, neonatal breathing, and survival. 2012 Nov 29 2
47 23152497 Histone demethylase KDM6B promotes epithelial-mesenchymal transition. 2012 Dec 28 3
48 21245294 Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming. 2011 Feb 1 1
49 20064925 Epithelial cell adhesion molecule regulation is associated with the maintenance of the undifferentiated phenotype of human embryonic stem cells. 2010 Mar 19 1
50 21209387 Role of H3K27 demethylases Jmjd3 and UTX in transcriptional regulation. 2010 1