Fatty Acids

peroxisome proliferator activated receptor alpha ; Rattus norvegicus







193 Article(s)
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1 35051553 Pdcd4 promotes lipid deposition by attenuating PPARα-mediated fatty acid oxidation in hepatocytes. 2022 Apr 5 1
2 35157213 Exploring the Pattern of Metabolic Alterations Causing Energy Imbalance via PPARα Dysregulation in Cardiac Muscle During Doxorubicin Treatment. 2022 May 2
3 33578161 Exposure to short-chain chlorinated paraffins inhibited PPARα-mediated fatty acid oxidation and stimulated aerobic glycolysis in vitro in human cells. 2021 Jun 10 1
4 33991387 Programming by Methyl Donor Deficiency during Pregnancy and Lactation Produces Cardiomyopathy in Adult Rats Subjected to High Fat Diet. 2021 Jul 1
5 34118565 Metabolic maturation of differentiating cardiosphere-derived cells. 2021 Jul 3
6 34445672 Mechanisms Mediating the Regulation of Peroxisomal Fatty Acid Beta-Oxidation by PPARα. 2021 Aug 20 1
7 34829565 Anti-NAFLD Effect of Djulis Hull and Its Major Compound, Rutin, in Mice with High-Fat Diet (HFD)-Induced Obesity. 2021 Oct 27 1
8 35222262 Medications Activating Tubular Fatty Acid Oxidation Enhance the Protective Effects of Roux-en-Y Gastric Bypass Surgery in a Rat Model of Early Diabetic Kidney Disease. 2021 1
9 31112599 PPARα/β Activation Alleviates Age-Associated Renal Fibrosis in Sprague Dawley Rats. 2020 Feb 14 2
10 31712968 Acute naloxone-precipitated morphine withdrawal elicits nausea-like somatic behaviors in rats in a manner suppressed by N-oleoylglycine. 2020 Feb 2
11 31950587 Effects and therapeutic mechanism of Yinzhihuang on steatohepatitis in rats induced by a high-fat, high-cholesterol diet. 2020 Mar 2
12 32141989 Ursolic Acid Improves Monocrotaline-Induced Right Ventricular Remodeling by Regulating Metabolism. 2020 Jun 2
13 32479954 Oleic acid stimulates monoamine efflux through PPAR-α: Differential effects in diet-induced obesity. 2020 Aug 15 2
14 33061495 Urolithins Attenuate Multiple Symptoms of Obesity in Rats Fed on a High-Fat Diet. 2020 1
15 30080446 Alterations in plasma acylcarnitine and amino acid profiles may indicate poor nutrition during the suckling period due to maternal intake of an unbalanced diet and may predict later metabolic dysfunction. 2019 Jan 1
16 30590197 Chronic treatment with the modified Longdan Xiegan Tang attenuates olanzapine-induced fatty liver in rats by regulating hepatic de novo lipogenesis and fatty acid beta-oxidation-associated gene expression mediated by SREBP-1c, PPAR-alpha and AMPK-alpha. 2019 Mar 25 2
17 30659956 Osthole inhibits oleic acid/lipopolysaccharide-induced lipid accumulation and inflammatory response through activating PPARα signaling pathway in cultured hepatocytes. 2019 May 1
18 30818137 Protective effect of cultured bear bile powder against dimethylnitrosamine-induced hepatic fibrosis in rats. 2019 Apr 1
19 30897468 Fine particles cause the abnormality of cardiac ATP levels via PPARɑ-mediated utilization of fatty acid and glucose using in vivo and in vitro models. 2019 Jun 1
20 31185430 Short-chain chlorinated paraffins (SCCPs) disrupt hepatic fatty acid metabolism in liver of male rat via interacting with peroxisome proliferator-activated receptor α (PPARα). 2019 Oct 15 3
21 31308847 Short-Term Activation of Peroxisome Proliferator-Activated Receptors α and γ Induces Tissue-Specific Effects on Lipid Metabolism and Fatty Acid Composition in Male Wistar Rats. 2019 2
22 31678905 Integration of metabolomics and transcriptomics reveals short-chain chlorinated paraffin-induced hepatotoxicity in male Sprague-Dawley rat. 2019 Dec 1
23 28760335 MicroRNA-21 regulates peroxisome proliferator-activated receptor alpha, a molecular mechanism of cardiac pathology in Cardiorenal Syndrome Type 4. 2018 Feb 2
24 29031784 Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomics for the investigation of the effect of Hugan Qingzhi on non-alcoholic fatty liver disease in rats. 2018 Feb 15 1
25 29115530 Curcumin suppresses Notch‑1 signaling: Improvements in fatty liver and insulin resistance in rats. 2018 Jan 1
26 29138817 Reduced triglyceride accumulation due to overactivation of farnesoid X receptor signaling contributes to impaired liver regeneration following 50% hepatectomy in extra‑cholestatic liver tissue. 2018 Jan 1
27 29311481 A PPAR Pan Agonist, MHY2013 Alleviates Age-Related Hepatic Lipid Accumulation by Promoting Fatty Acid Oxidation and Suppressing Inflammation. 2018 1
28 29474705 PCB126 Inhibits the Activation of AMPK-CREB Signal Transduction Required for Energy Sensing in Liver. 2018 Jun 1 1
29 29860222 Acylated ghrelin induces but deacylated ghrelin prevents hepatic steatosis and insulin resistance in lean rats: Effects on DAG/ PKC/JNK pathway. 2018 Sep 1
30 29961332 Sodium Butyrate Ameliorates High-Fat-Diet-Induced Non-alcoholic Fatty Liver Disease through Peroxisome Proliferator-Activated Receptor α-Mediated Activation of β Oxidation and Suppression of Inflammation. 2018 Jul 25 1
31 30328346 Apoptotic germ cells regulate Sertoli cell lipid storage and fatty acid oxidation. 2018 Dec 1
32 30564122 Pro-angiogenic Role of Danqi Pill Through Activating Fatty Acids Oxidation Pathway Against Coronary Artery Disease. 2018 1
33 27271251 Oxidized tea polyphenols prevent lipid accumulation in liver and visceral white adipose tissue in rats. 2017 Sep 1
34 28549240 Dietary salecan reverts partially the metabolic gene expressions and NMR-based metabolomic profiles from high-fat-diet-induced obese rats. 2017 Sep 1
35 29903312 [Effects of perfluorooctanoic acid on oxidative stress and PPARα and its related CYP4A1 gene expression in rat liver]. 2017 Sep 1
36 26396156 PCB126-Induced Disruption in Gluconeogenesis and Fatty Acid Oxidation Precedes Fatty Liver in Male Rats. 2016 Jan 1
37 26908215 Anti-Obesity Effects of Aster spathulifolius Extract in High-Fat Diet-Induced Obese Rats. 2016 Apr 1
38 26918671 Peroxisome proliferator-activated receptor γ activation favours selective subcutaneous lipid deposition by coordinately regulating lipoprotein lipase modulators, fatty acid transporters and lipogenic enzymes. 2016 Jul 2
39 27187182 A High Phosphorus Diet Affects Lipid Metabolism in Rat Liver: A DNA Microarray Analysis. 2016 3
40 27279428 Genomic expression profiling and bioinformatics analysis on diabetic nephrology with ginsenoside Rg3. 2016 Aug 2
41 27413362 Testosterone Replacement Modulates Cardiac Metabolic Remodeling after Myocardial Infarction by Upregulating PPARα. 2016 4
42 25186103 5-Caffeoylquinic acid decreases diet-induced obesity in rats by modulating PPARα and LXRα transcription. 2015 Jul 2
43 25377249 The dipeptide H-Trp-Arg-OH (WR) Is a PPARα agonist and reduces hepatic lipid accumulation in lipid-loaded H4IIE cells. 2015 Jan 1
44 25701199 Cyanidin and malvidin in aqueous extracts of black carrots fermented with Aspergillus oryzae prevent the impairment of energy, lipid and glucose metabolism in estrogen-deficient rats by AMPK activation. 2015 Mar 1
45 25888880 Treatment of lactating sows with clofibrate as a synthetic agonist of PPARα does not influence milk fat content and gains of litters. 2015 Mar 7 1
46 25976666 Ligand specific variation in cardiac response to stimulation of peroxisome proliferator-activated receptor-alpha in spontaneously hypertensive rat. 2015 Aug 2
47 26160389 Celecoxib and Ibuprofen Restore the ATP Content and the Gluconeogenesis Activity in the Liver of Walker-256 Tumor-Bearing Rats. 2015 1
48 26171116 Genome-Wide Expression Profiling of Anoxia/Reoxygenation in Rat Cardiomyocytes Uncovers the Role of MitoKATP in Energy Homeostasis. 2015 1
49 26558146 Role of peroxisome proliferator-activated receptors alpha and gamma in gastric ulcer: An overview of experimental evidences. 2015 Nov 6 1
50 26696906 Maternal Melatonin Therapy Rescues Prenatal Dexamethasone and Postnatal High-Fat Diet Induced Programmed Hypertension in Male Rat Offspring. 2015 1