Doxorubicin

BCL2, apoptosis regulator ; Rattus norvegicus







78 Article(s)
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1 34913064 Substance P prevents doxorubicin‑induced cardiomyocyte injury by regulating apoptosis and autophagy: In vitro and in vivo evidence. 2022 Feb 1
2 34968927 Isoliquiritigenin prevents Doxorubicin-induced hepatic damage in rats by upregulating and activating SIRT1. 2022 Feb 1
3 35322164 LCZ696 ameliorates doxorubicin-induced cardiomyocyte toxicity in rats. 2022 Mar 23 1
4 35470029 Scutellarin attenuates doxorubicin-induced oxidative stress, DNA damage, mitochondrial dysfunction, apoptosis and autophagy in H9c2 cells, cardiac fibroblasts and HUVECs. 2022 Aug 1
5 35559248 Dimethyl Fumarate Ameliorates Doxorubicin-Induced Cardiotoxicity By Activating the Nrf2 Pathway. 2022 1
6 35624893 Anti-Inflammatory, Anti-Apoptotic, and Antioxidant Roles of Honey, Royal Jelly, and Propolis in Suppressing Nephrotoxicity Induced by Doxorubicin in Male Albino Rats. 2022 May 23 1
7 33460662 Berberine ameliorates doxorubicin-induced cognitive impairment (chemobrain) in rats. 2021 Mar 15 2
8 34029952 Comparative study on beneficial effects of vitamins B and D in attenuating doxorubicin induced cardiotoxicity in rats: Emphasis on calcium homeostasis. 2021 Aug 1
9 34153024 Salvianolic Acid A Protects H9C2 Cardiomyocytes from Doxorubicin-Induced Damage by Inhibiting NFKB1 Expression Thereby Downregulating Long-Noncoding RNA (lncRNA) Plasmacytoma Variant Translocation 1 (PVT1). 2021 Jun 21 1
10 34273911 Protective effect of valsartan against doxorubicin-induced cardiotoxicity: Histopathology and metabolomics in vivo study. 2021 Sep 2
11 31811646 Doxorubicin-induces NFAT/Fas/FasL cardiac apoptosis in rats through activation of calcineurin and P38 MAPK and inhibition of mTOR signalling pathways. 2020 Apr 1
12 31853613 Protection from doxorubicin-induced nephrotoxicity by clindamycin: novel antioxidant, anti-inflammatory and anti-apoptotic roles. 2020 Apr 1
13 31858651 Calycosin ameliorates doxorubicin-induced cardiotoxicity by suppressing oxidative stress and inflammation via the sirtuin 1-NOD-like receptor protein 3 pathway. 2020 Mar 1
14 31881187 Teneligliptin prevents doxorubicin-induced inflammation and apoptosis in H9c2 cells. 2020 Apr 15 1
15 32068341 Melatonin attenuates doxorubicin-induced cardiotoxicity through preservation of YAP expression. 2020 Mar 1
16 32388215 Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro. 2020 Jul 1
17 32435528 Luteolin attenuates doxorubicin-induced cardiotoxicity by modulating the PHLPP1/AKT/Bcl-2 signalling pathway. 2020 2
18 32704131 Cardioprotective effects of miR-34a silencing in a rat model of doxorubicin toxicity. 2020 Jul 23 2
19 32855734 Mitochondria-associated protein LRPPRC exerts cardioprotective effects against doxorubicin-induced toxicity, potentially via inhibition of ROS accumulation. 2020 Oct 1
20 32958254 Adiponectin agonist ADP355 ameliorates doxorubicin-induced cardiotoxicity by decreasing cardiomyocyte apoptosis and oxidative stress. 2020 Dec 10 1
21 32968640 MiR-181c protects cardiomyocyte injury by preventing cell apoptosis through PI3K/Akt signaling pathway. 2020 Aug 1
22 32992421 [Dihydromyricin alleviates doxorubicin-induced myocardial injury by inhibiting NLRP3 inflammasome in rats]. 2020 Oct 8 2
23 30827825 Deciphering the molecular mechanism during doxorubicin-mediated oxidative stress, apoptosis through Nrf2 and PGC-1α in a rat testicular milieu. 2019 Mar 2
24 30836069 β-Caryophyllene, a natural bicyclic sesquiterpene attenuates doxorubicin-induced chronic cardiotoxicity via activation of myocardial cannabinoid type-2 (CB2) receptors in rats. 2019 May 1 1
25 30991846 Mesenchymal stem cells pretreated with platelet-rich plasma modulate doxorubicin-induced cardiotoxicity. 2019 Jul 2
26 31048226 Effects of high-intensity interval training on the expression of microRNA-499 and pro- and anti-apoptotic genes in doxorubicin-cardiotoxicity in rats. 2019 Jul - Aug 4
27 31093684 Acylated ghrelin prevents doxorubicin-induced cardiac intrinsic cell death and fibrosis in rats by restoring IL-6/JAK2/STAT3 signaling pathway and inhibition of STAT1. 2019 Sep 1
28 31100273 Protective effect of morin on doxorubicin-induced hepatorenal toxicity in rats. 2019 Aug 1 1
29 31216443 β-caryophyllene, a dietary phytocannabinoid attenuates oxidative stress, inflammation, apoptosis and prevents structural alterations of the myocardium against doxorubicin-induced acute cardiotoxicity in rats: An in vitro and in vivo study. 2019 Sep 5 1
30 31412018 Irisin Enhances Doxorubicin-Induced Cell Apoptosis in Pancreatic Cancer by Inhibiting the PI3K/AKT/NF-κB Pathway. 2019 Aug 14 2
31 31434946 Extracorporeal shock waves protect cardiomyocytes from doxorubicin-induced cardiomyopathy by upregulating survivin via the integrin-ILK-Akt-Sp1/p53 axis. 2019 Aug 21 1
32 29660505 GCN2 deficiency ameliorates doxorubicin-induced cardiotoxicity by decreasing cardiomyocyte apoptosis and myocardial oxidative stress. 2018 Jul 1
33 30025410 MicroRNA-29b Regulates the Mitochondria-Dependent Apoptotic Pathway by Targeting Bax in Doxorubicin Cardiotoxicity. 2018 2
34 27607345 Protective Role of GPER Agonist G-1 on Cardiotoxicity Induced by Doxorubicin. 2017 Jul 1
35 28780599 Liraglutide ameliorates cardiotoxicity induced by doxorubicin in rats through the Akt/GSK-3β signaling pathway. 2017 Nov 1
36 28928469 Activation of miR-34a-5p/Sirt1/p66shc pathway contributes to doxorubicin-induced cardiotoxicity. 2017 Sep 19 1
37 28962145 Attenuation of doxorubicin-induced cardiotoxicity by esculetin through modulation of Bmi-1 expression. 2017 Sep 1
38 26675978 Resveratrol protects cardiomyocytes from doxorubicin-induced apoptosis through the AMPK/P53 pathway. 2016 Feb 3
39 26818447 Effect of metformin and sitagliptin on doxorubicin-induced cardiotoxicity in adult male albino rats. 2016 Nov 2
40 26974593 Effect of valsartan on cardiac senescence and apoptosis in a rat model of cardiotoxicity. 2016 Jun 1
41 27284328 Paeoniflorin inhibits doxorubicin-induced cardiomyocyte apoptosis by downregulating microRNA-1 expression. 2016 Jun 1
42 27811390 Fullerenol/doxorubicin nanocomposite mitigates acute oxidative stress and modulates apoptosis in myocardial tissue. 2016 Dec 2 1
43 24509133 Chrysin alleviates acute doxorubicin cardiotoxicity in rats via suppression of oxidative stress, inflammation and apoptosis. 2014 Apr 5 1
44 24902966 Quercetin attenuates doxorubicin cardiotoxicity by modulating Bmi-1 expression. 2014 Oct 1
45 25220638 Liguzinediol improved the heart function and inhibited myocardial cell apoptosis in rats with heart failure. 2014 Oct 1
46 23519142 Neuregulin-1 attenuates doxorubicin-induced autophagy in neonatal rat cardiomyocytes. 2013 Aug 2
47 23896563 α-Linolenic acid attenuates doxorubicin-induced cardiotoxicity in rats through suppression of oxidative stress and apoptosis. 2013 Oct 1
48 24072175 Salidroside improves doxorubicin-induced cardiac dysfunction by suppression of excessive oxidative stress and cardiomyocyte apoptosis. 2013 Dec 1
49 24404586 The role of autophagy in doxorubicin-induced cardiotoxicity. 2013 Dec 5 1
50 21476075 Taurine protects rat testes against doxorubicin-induced oxidative stress as well as p53, Fas and caspase 12-mediated apoptosis. 2012 May 1