abemaciclib

cyclin dependent kinase 6 ; Homo sapiens







5 Article(s)
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Pub. Year
#Total Relationships
1 32781837 Abemaciclib, a CDK4 and CDK6 inhibitor for the treatment of metastatic breast cancer. 2020 Nov 1
2 31875784 Molecular Dynamics Mechanisms of the Inhibitory Effects of Abemaciclib, Hymenialdisine, and Indirubin on CDK-6. 2019 1
3 27748766 Acquired CDK6 amplification promotes breast cancer resistance to CDK4/6 inhibitors and loss of ER signaling and dependence. 2017 Apr 20 1
4 24850847 Semi-mechanistic pharmacokinetic/pharmacodynamic modeling of the antitumor activity of LY2835219, a new cyclin-dependent kinase 4/6 inhibitor, in mice bearing human tumor xenografts. 2014 Jul 15 2
5 24919854 Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine. 2014 Oct 1