Adenosine Triphosphate

cyclin dependent kinase 6 ; Homo sapiens







7 Article(s)
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1 33890551 Predictive hybrid paradigm for cytotoxic activity of 1,3,4-thiadiazole derivatives as CDK6 inhibitors against human (MCF-7) breast cancer cell line and its structural modifications: rational for novel cancer therapeutics. 2021 Apr 23 2
2 34771669 Inhibitors, PROTACs and Molecular Glues as Diverse Therapeutic Modalities to Target Cyclin-Dependent Kinase. 2021 Nov 2 1
3 30935795 Selective degradation of CDK6 by a palbociclib based PROTAC. 2019 Jun 1 1
4 29108955 Reduced state transition barrier of CDK6 from open to closed state induced by Thr177 phosphorylation and its implication in binding modes of inhibitors. 2018 Mar 1
5 29050219 Preclinical characterization of abemaciclib in hormone receptor positive breast cancer. 2017 Sep 19 1
6 11278443 Cell cycle and biochemical effects of PD 0183812. A potent inhibitor of the cyclin D-dependent kinases CDK4 and CDK6. 2001 May 18 1
7 9751050 Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a. 1998 Sep 17 1