| 1 |
35343565 | Reciprocal regulation of p21 and Chk1 controls the cyclin D1-RB pathway to mediate senescence onset after G2 arrest. | 2022 Apr 15 |
1 |
| 2 |
35361964 | Cell cycle regulation: p53-p21-RB signaling. | 2022 May |
1 |
| 3 |
33516252 | The circular RNA circZFR phosphorylates Rb promoting cervical cancer progression by regulating the SSBP1/CDK2/cyclin E1 complex. | 2021 Jan 30 |
1 |
| 4 |
34658297 | Polyphyllin I, a lethal partner of Palbociclib, suppresses non-small cell lung cancer through activation of p21/CDK2/Rb pathway in vitro and in vivo. | 2021 Dec |
1 |
| 5 |
32041019 | Reactive oxygen species-mediated cellular genotoxic stress is involved in 1-nitropyrene-induced trophoblast cycle arrest and fetal growth restriction. | 2020 May |
1 |
| 6 |
32899250 | PI3K p110α Blockade Enhances Anti-Tumor Efficacy of Abemaciclib in Human Colorectal Cancer Cells. | 2020 Sep 3 |
1 |
| 7 |
33039146 | Cyclin Y binds and activates CDK4 to promote the G1/S phase transition in hepatocellular carcinoma cells via Rb signaling. | 2020 Dec 17 |
1 |
| 8 |
30508677 | Cyclin-dependent protein serine/threonine kinase inhibitors as anticancer drugs. | 2019 Jan |
1 |
| 9 |
26783196 | Phosphorylated retinoblastoma protein is a potential predictive marker of irinotecan efficacy for colorectal cancer. | 2016 Mar |
2 |
| 10 |
24240190 | Arterial territory-specific phosphorylated retinoblastoma protein species and CDK2 promote differences in the vascular smooth muscle cell response to mitogens. | 2014 |
2 |
| 11 |
22768064 | Epstein-Barr virus BGLF4 kinase retards cellular S-phase progression and induces chromosomal abnormality. | 2012 |
1 |
| 12 |
21421237 | Costunolide induces apoptosis through nuclear calcium2+ overload and DNA damage response in human prostate cancer. | 2011 May |
1 |
| 13 |
20473330 | Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure. | 2010 Jul 15 |
1 |
| 14 |
16759374 | Cdk2 and Cdk4 cooperatively control the expression of Cdc2. | 2006 Jun 6 |
1 |
| 15 |
16861913 | Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway. | 2006 Aug |
1 |
| 16 |
15355984 | Construction of a cyclin D1-Cdk2 fusion protein to model the biological functions of cyclin D1-Cdk2 complexes. | 2004 Nov 12 |
2 |
| 17 |
11919196 | Cyclin E is a target of WT1 transcriptional repression. | 2002 May 31 |
1 |
| 18 |
11359910 | Retinoblastoma tumor suppressor protein signals through inhibition of cyclin-dependent kinase 2 activity to disrupt PCNA function in S phase. | 2001 Jun |
3 |
| 19 |
10942587 | TGF-beta-mediated cell cycle arrest of HPV16-immortalized human ectocervical cells correlates with decreased E6/E7 mRNA and increased p53 and p21(WAF-1) expression. | 2000 Aug 25 |
1 |
| 20 |
11175348 | PKCeta associates with cyclin E/cdk2/p21 complex, phosphorylates p21 and inhibits cdk2 kinase in keratinocytes. | 2000 Dec 14 |
2 |
| 21 |
9990305 | Differential regulation of p27kip1 levels and CDK activities by hypertrophic and hyperplastic agents in vascular smooth muscle cells. | 1999 Jan 11 |
1 |
| 22 |
10499802 | Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1. | 1999 Sep 17 |
1 |
| 23 |
8635520 | Behavior of the cell cycle-associated proteins in an unusual G0-arrestable cancer cell line. | 1996 May 25 |
1 |
| 24 |
8033212 | Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. | 1994 Jul 15 |
2 |
| 25 |
8242751 | The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. | 1993 Nov 19 |
2 |
| 26 |
8253384 | Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins. | 1993 Dec |
1 |