| 1 |
35614852 | Conserved Cdk inhibitors show unique structural responses to tyrosine phosphorylation. | 2022 Jun 21 |
1 |
| 2 |
34156324 | Activation of CDC25A phosphatase is limited by CDK2/cyclin A-mediated feedback inhibition. | 2021 Jul |
1 |
| 3 |
34446542 | NP-ALT, a Liposomal:Peptide Drug, Blocks p27Kip1 Phosphorylation to Induce Oxidative Stress, Necroptosis, and Regression in Therapy-Resistant Breast Cancer Cells. | 2021 Nov |
2 |
| 4 |
30976006 | Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation. | 2019 Apr 11 |
1 |
| 5 |
29330290 | Dual Inhibition of CDK4 and CDK2 via Targeting p27 Tyrosine Phosphorylation Induces a Potent and Durable Response in Breast Cancer Cells. | 2018 Mar |
4 |
| 6 |
29718700 | Relationship between intermuscular adipose tissue infiltration and myostatin before and after aerobic exercise training. | 2018 Sep 1 |
1 |
| 7 |
30035169 | Targeting p27 tyrosine phosphorylation as a modality to inhibit CDK4 and CDK2 and cause cell cycle arrest in breast cancer cells. | 2018 May |
1 |
| 8 |
24872417 | Phosphorylation of cyclin-dependent kinase 5 (Cdk5) at Tyr-15 is inhibited by Cdk5 activators and does not contribute to the activation of Cdk5. | 2014 Jul 11 |
1 |
| 9 |
25084614 | CHK1 plays a critical role in the anti-leukemic activity of the wee1 inhibitor MK-1775 in acute myeloid leukemia cells. | 2014 Aug 1 |
1 |
| 10 |
21697511 | Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins. | 2012 Feb 21 |
1 |
| 11 |
22399317 | Intrinsic protein flexibility in regulation of cell proliferation: advantages for signaling and opportunities for novel therapeutics. | 2012 |
1 |
| 12 |
19858290 | A bifunctional regulatory element in human somatic Wee1 mediates cyclin A/Cdk2 binding and Crm1-dependent nuclear export. | 2010 Jan |
1 |
| 13 |
20422243 | Structural and functional relationship between the Ph1 locus protein 5B2 in wheat and CDK2 in mammals. | 2010 May |
2 |
| 14 |
18495657 | Mesalazine negatively regulates CDC25A protein expression and promotes accumulation of colon cancer cells in S phase. | 2008 Jun |
1 |
| 15 |
18617527 | Activation of Cdk2 stimulates proteasome-dependent truncation of tyrosine phosphatase SHP-1 in human proliferating intestinal epithelial cells. | 2008 Sep 12 |
1 |
| 16 |
18627125 | Regulation of cell division by intrinsically unstructured proteins: intrinsic flexibility, modularity, and signaling conduits. | 2008 Jul 22 |
1 |
| 17 |
17095507 | How tyrosine 15 phosphorylation inhibits the activity of cyclin-dependent kinase 2-cyclin A. | 2007 Feb 2 |
3 |
| 18 |
16818510 | PM-20, a novel inhibitor of Cdc25A, induces extracellular signal-regulated kinase 1/2 phosphorylation and inhibits hepatocellular carcinoma growth in vitro and in vivo. | 2006 Jun |
1 |
| 19 |
16930563 | Fluorinated Cpd 5, a pure arylating K-vitamin derivative, inhibits human hepatoma cell growth by inhibiting Cdc25 and activating MAPK. | 2006 Nov 15 |
1 |
| 20 |
16969075 | H32, a non-quinone sulfone analog of vitamin K3, inhibits human hepatoma cell growth by inhibiting Cdc25 and activating ERK. | 2006 Oct |
1 |
| 21 |
16177568 | Aberrant splicing of cables gene, a CDK regulator, in human cancers. | 2005 Nov |
2 |
| 22 |
14767478 | Cyclin A/Cdk2 complexes regulate activation of Cdk1 and Cdc25 phosphatases in human cells. | 2004 Apr 22 |
1 |
| 23 |
15136770 | S-phase inhibition of cell cycle progression by a novel class of pyridopyrimidine tyrosine kinase inhibitors. | 2004 Jun |
1 |
| 24 |
13678583 | UV irradiation triggers ubiquitin-dependent degradation of p21(WAF1) to promote DNA repair. | 2003 Sep 5 |
1 |
| 25 |
14551212 | Phosphorylations of cyclin-dependent kinase 2 revisited using two-dimensional gel electrophoresis. | 2003 Dec 26 |
1 |
| 26 |
12181445 | Inhibition of cyclin-dependent kinase 2 by the Chk1-Cdc25A pathway during the S-phase checkpoint activated by fludarabine: dysregulation by 7-hydroxystaurosporine. | 2002 Sep |
3 |
| 27 |
12356752 | Dual G1 and G2 phase inhibition by a novel, selective Cdc25 inhibitor 6-chloro-7-[corrected](2-morpholin-4-ylethylamino)-quinoline-5,8-dione. | 2002 Dec 6 |
2 |
| 28 |
12359725 | Stimulation of the Raf/MEK/ERK cascade is necessary and sufficient for activation and Thr-160 phosphorylation of a nuclear-targeted CDK2. | 2002 Dec 6 |
1 |
| 29 |
11585773 | Cables enhances cdk2 tyrosine 15 phosphorylation by Wee1, inhibits cell growth, and is lost in many human colon and squamous cancers. | 2001 Oct 1 |
3 |
| 30 |
11716299 | Checkpoints for vesicular traffic? | 2001 |
1 |
| 31 |
10827953 | Rapid destruction of human Cdc25A in response to DNA damage. | 2000 May 26 |
1 |
| 32 |
9989807 | A rate limiting function of cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2. | 1999 Jan 21 |
4 |
| 33 |
10454565 | Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases. | 1999 Sep |
1 |
| 34 |
10597298 | Dual G1 and G2/M phase inhibition by SC-alpha alpha delta 9, a combinatorially derived Cdc25 phosphatase inhibitor. | 1999 Nov 25 |
1 |
| 35 |
9632724 | Critical role for the 310 helix region of p57(Kip2) in cyclin-dependent kinase 2 inhibition and growth suppression. | 1998 Jun 26 |
1 |
| 36 |
9637776 | Inhibition of Cdk2 activation by selected tyrphostins causes cell cycle arrest at late G1 and S phase. | 1998 Jun 15 |
2 |
| 37 |
8662825 | Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage. | 1996 May 31 |
1 |
| 38 |
8668211 | Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest. | 1996 Jul |
1 |
| 39 |
8674031 | Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells. | 1996 Jul 1 |
1 |
| 40 |
8806683 | Interaction of cyclin-dependent kinase 2 and the Lyn tyrosine kinase in cells treated with 1-beta-D-arabinofuranosylcytosine. | 1996 Sep 5 |
1 |
| 41 |
8260651 | Transmembrane signaling by the interleukin-2 receptor: progress and conundrums. | 1993 Oct |
1 |