Tretinoin

cyclin dependent kinase 2 ; Homo sapiens







33 Article(s)
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1 31740384 CDK2 suppression synergizes with all-trans-retinoic acid to overcome the myeloid differentiation blockade of AML cells. 2020 Jan 4
2 32032659 Roscovitine enhances All-trans retinoic acid (ATRA)-induced leukemia cell differentiation: Novel effects on signaling molecules for a putative Cdk2 inhibitor. 2020 Jul 1
3 30859584 RA promotes proliferation of primordial germ cell-like cells differentiated from porcine skin-derived stem cells. 2019 Aug 2
4 28412739 Retinoic acid receptor alpha drives cell cycle progression and is associated with increased sensitivity to retinoids in T-cell lymphoma. 2017 Apr 18 1
5 24635079 All-trans retinoic acid induces cell-cycle arrest in human cutaneous squamous carcinoma cells by inhibiting the mitogen-activated protein kinase-activated protein 1 pathway. 2014 Apr 1
6 24646031 Role of cell cycle regulatory molecules in retinoic acid- and vitamin D3-induced differentiation of acute myeloid leukaemia cells. 2014 Jun 4
7 17960384 Combination of all-trans retinoic acid and interferon-gamma upregulated p27(kip1) and down regulated CDK2 to cause cell cycle arrest leading to differentiation and apoptosis in human glioblastoma LN18 (PTEN-proficient) and U87MG (PTEN-deficient) cells. 2008 Aug 1
8 18006504 A MAPK-positive feedback mechanism for BLR1 signaling propels retinoic acid-triggered differentiation and cell cycle arrest. 2008 Feb 15 1
9 18539384 Epstein-Barr virus latent membrane protein 1 suppresses the growth-inhibitory effect of retinoic acid by inhibiting retinoic acid receptor-beta2 expression via DNA methylation. 2008 Oct 18 2
10 18773862 Retinoic acid and sodium butyrate as cell cycle regulators in the treatment of oral squamous carcinoma cells. 2008 2
11 16765349 Increased p21 expression and complex formation with cyclin E/CDK2 in retinoid-induced pre-B lymphoma cell apoptosis. 2006 Jun 26 2
12 16766008 Enhancement of caffeic acid phenethyl ester on all-trans retinoic acid-induced differentiation in human leukemia HL-60 cells. 2006 Oct 1 1
13 15715961 CDK2/4 regulate retinoic acid-induced G1 arrest in hepatocellular carcinoma cells. 2005 Mar 5
14 15587392 The effect of sodium butyrate in combination with ATRA on the proliferation/differentiation of SKM-1. 2004 1
15 14587026 Differential regulation of protein expression, growth and apoptosis by natural and synthetic retinoids. 2003 Nov 1 2
16 12012012 All trans retinoic acid enhances CDDP-induced apoptosis: modulation of the CDDP effect on cell cycle progression. 2002 Jun 3
17 12421932 Retinoic acid stimulates the cell cycle machinery in normal T cells: involvement of retinoic acid receptor-mediated IL-2 secretion. 2002 Nov 15 1
18 11753676 Cell cycle genes as targets of retinoid induced ovarian tumor cell growth suppression. 2001 Nov 29 1
19 11753686 The retinoic acid receptor antagonist, BMS453, inhibits normal breast cell growth by inducing active TGFbeta and causing cell cycle arrest. 2001 Nov 29 1
20 10644979 p27Kip1 accumulation is associated with retinoic-induced neuroblastoma differentiation: evidence of a decreased proteasome-dependent degradation. 2000 Jan 6 1
21 10896783 Retinoic acid-mediated G1 arrest is associated with induction of p27(Kip1) and inhibition of cyclin-dependent kinase 3 in human lung squamous carcinoma CH27 cells. 2000 Aug 1 2
22 11030153 Complex regulation of CDKs and G1 arrest during the granulocytic differentiation of human myeloblastic leukemia ML-1 cells. 2000 Sep 21 2
23 11063125 Retinoic acid induces neuronal differentiation of embryonal carcinoma cells by reducing proteasome-dependent proteolysis of the cyclin-dependent inhibitor p27. 2000 Oct 1
24 10094816 Induction of p21(CIP1/Waf1) and activation of p34(cdc2) involved in retinoic acid-induced apoptosis in human hepatoma Hep3B cells. 1999 Apr 10 2
25 10438723 Retinoic acid prevents phosphorylation of pRB in normal human B lymphocytes: regulation of cyclin E, cyclin A, and p21(Cip1). 1999 Aug 15 1
26 10706449 Inhibition of myeloma cell growth by all-trans retinoic acid is associated with upregulation of p21WAF1 and dephosphorylation of the retinoblastoma protein. 1999 Oct 3
27 11601206 [Study of the role of cyclin-dependent kinases (CDKs) in retinoic acid (RA) inducing HL-60 cell differentiation]. 1999 Feb 5
28 9716179 Increased cdc2 and cdk2 kinase activity by retinoid X receptor gamma-mediated transcriptional down-regulation of the cyclin-dependent kinase inhibitor p21Cip1/WAF1 correlates with terminal differentiation of squamous cell carcinoma lines. 1998 Aug 1
29 9778049 Retinoic acid-mediated growth arrest of EBV-immortalized B lymphocytes is associated with multiple changes in G1 regulatory proteins: p27Kip1 up-regulation is a relevant early event. 1998 Oct 8 5
30 9259311 CDK2 is a target for retinoic acid-mediated growth inhibition in MCF-7 human breast cancer cells. 1997 Aug 9
31 9366521 Retinoic acid and the cyclin dependent kinase inhibitors synergistically alter proliferation and morphology of U343 astrocytoma cells. 1997 Oct 23 1
32 8788034 Differential effects of retinoids and antiestrogens on cell cycle progression and cell cycle regulatory genes in human breast cancer cells. 1996 Jan 1
33 17180006 Signals transduced via insulin-like growth factor I receptor (IGF(R)) mediate resistance to retinoic acid-induced cell growth arrest in a human neuroblastoma cell line. 1994 Jul 1