Paclitaxel

caspase 9 ; Homo sapiens







42 Article(s)
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1 35075596 Paclitaxel Promotes Oxidative Stress-Mediated Human Laryngeal Squamous Tumor Cell Death through the Stimulation of Calcium and Zinc Signaling Pathways: No Synergic Action of Melatonin. 2022 May 1
2 35240000 Zerumbone-induced reactive oxygen species-mediated oxidative stress re-sensitizes breast cancer cells to paclitaxel. 2022 Mar 3 1
3 33422634 A novel synergistic anticancer effect of fungal cholestanol glucoside and paclitaxel: Apoptosis induced by an intrinsic pathway through ROS generation in cervical cancer cell line (HeLa). 2021 Apr 1
4 33848578 Synergistic effects of green tea extract and paclitaxel in the induction of mitochondrial apoptosis in ovarian cancer cell lines. 2021 Jun 30 1
5 34363313 The stressosome, a caspase-8-activating signalling complex assembled in response to cell stress in an ATG5-mediated manner. 2021 Sep 1
6 34435645 Proteasome inhibitors decrease paclitaxel‑induced cell death in nasopharyngeal carcinoma with the accumulation of CDK1/cyclin B1. 2021 Oct 1
7 34479918 The Mechanisms of the Growth Inhibitory Effects of Paclitaxel on Gefitinib-resistant Non-small Cell Lung Cancer Cells. 2021 Sep-Oct 1
8 34768915 Ursolic Acid Accelerates Paclitaxel-Induced Cell Death in Esophageal Cancer Cells by Suppressing Akt/FOXM1 Signaling Cascade. 2021 Oct 25 1
9 34873207 The effect of paclitaxel on apoptosis, autophagy and mitotic catastrophe in AGS cells. 2021 Dec 6 1
10 31512793 MicroRNA-193a and taxol combination: A new strategy for treatment of colorectal cancer. 2020 Feb 1
11 30229430 Synergistic Anticancer Effect of a Combination of Paclitaxel and 5-Demethylnobiletin Against Lung Cancer Cell Line In Vitro and In Vivo. 2019 Apr 1
12 31675995 β-arrestin-2 up-regulates toll-like receptor 2 signaling and inhibits apoptosis in human endometrial cancer heterotransplants in nude mice. 2019 Nov 1 1
13 29416675 Phosphorylation of caspase-9 at Thr125 directs paclitaxel resistance in ovarian cancer. 2018 Jan 2 2
14 30249901 Four-and-a-half LIM protein 1 promotes paclitaxel resistance in hepatic carcinoma cells through the regulation of caspase-3 activation. 2018 Sep 3
15 27716527 Nanomedicine-based paclitaxel induced apoptotic signaling pathways in A562 leukemia cancer cells. 2017 Jan 1 1
16 28237486 Targeted inhibition of Notch1 gene enhances the killing effects of paclitaxel on triple negative breast cancer cells. 2017 Feb 1
17 26573761 MiR-106b~25 cluster regulates multidrug resistance in an ABC transporter-independent manner via downregulation of EP300. 2016 Feb 1
18 27304668 Glaucarubinone sensitizes KB cells to paclitaxel by inhibiting ABC transporters via ROS-dependent and p53-mediated activation of apoptotic signaling pathways. 2016 Jul 5 1
19 25633416 3,3'-Diindolylmethane potentiates paclitaxel-induced antitumor effects on gastric cancer cells through the Akt/FOXM1 signaling cascade. 2015 Apr 1
20 24520227 Synergistic Effect of COX-2 Inhibitor on Paclitaxel-Induced Apoptosis in the Human Ovarian Cancer Cell Line OVCAR-3. 2014 Jan 1
21 25089613 Oxygen-carbon nanotubes as a chemotherapy sensitizer for paclitaxel in breast cancer treatment. 2014 1
22 23735541 Apoptosis induced by paclitaxel via Bcl-2, Bax and caspases 3 and 9 activation in NB4 human leukaemia cells is not modulated by ERK inhibition. 2013 Nov 1
23 24023282 Targeting ovarian cancer and chemoresistance through selective inhibition of sphingosine kinase-2 with ABC294640. 2013 Sep 1
24 21074392 Involvement of oxidative stress in taxol-induced apoptosis in chronic myelogenous leukemia K562 cells. 2012 May 6
25 21622622 SRSF1 regulates the alternative splicing of caspase 9 via a novel intronic splicing enhancer affecting the chemotherapeutic sensitivity of non-small cell lung cancer cells. 2011 Jul 2
26 19661300 Comparison of cell death-inducing effect of novel taxane SB-T-1216 and paclitaxel in breast cancer cells. 2009 Aug 1
27 19957654 [Synergistic effects and mechanisms of combined tumor necrosis factor-related apoptosis-inducing ligand and chemotherapeutic drugs or radiotherapy in killing laryngeal squamous carcinoma cells in vitro]. 2009 Jul 1
28 18710614 [Effects of trichostatin A and paclitaxel on apoptosis and mitochondrial membrane potential of human endometrial carcinoma Ark2 cells]. 2008 Aug 2
29 19087722 [Effects of trichostatin A and paclitaxel on apoptosis and microtubule stabilization in endometrial carcinoma cells: an in vitro research]. 2008 Sep 9 1
30 17652622 Apaf-1 and caspase-9 deficiency prevents apoptosis in a Bax-controlled pathway and promotes clonogenic survival during paclitaxel treatment. 2007 Nov 15 3
31 16895478 Treatment of MCF-7 cells with taxol and etoposide induces distinct alterations in the expression of apoptosis-related genes BCL2, BCL2L12, BAX, CASPASE-9 and FAS. 2006 Aug 1
32 17121923 Histone deacetylase inhibitors and paclitaxel cause synergistic effects on apoptosis and microtubule stabilization in papillary serous endometrial cancer cells. 2006 Nov 1
33 15713893 Src inhibition enhances paclitaxel cytotoxicity in ovarian cancer cells by caspase-9-independent activation of caspase-3. 2005 Feb 1
34 16170024 Potentiation of paclitaxel-induced apoptosis by the novel cyclin-dependent kinase inhibitor NU6140: a possible role for survivin down-regulation. 2005 Sep 2
35 14726646 Arsenic trioxide and paclitaxel induce apoptosis by different mechanisms. 2004 Mar 1
36 12644839 Reversal of Taxol resistance in hepatoma by cyclosporin A: involvement of the PI-3 kinase-AKT 1 pathway. 2003 Mar 24 1
37 11677238 Lack of correlation between caspase activation and caspase activity assays in paclitaxel-treated MCF-7 breast cancer cells. 2002 Jan 4 3
38 12032672 Taxol-induced apoptosis in human SKOV3 ovarian and MCF7 breast carcinoma cells is caspase-3 and caspase-9 independent. 2002 Jun 2
39 12389115 Involvement of mitochondrial pathway in Taxol-induced apoptosis of human T24 bladder cancer cells. 2002 Oct 2
40 11489796 Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an RB- and schedule-dependent manner. See: E. A. Sausville, Combining cytotoxics and 17-allylamino, 17-demethoxygeldanamycin: sequence and tumor biology matters, Clin. Cancer Res., 7: 2155-2158, 2001. 2001 Aug 1
41 11600533 Cytochrome c release is upstream to activation of caspase-9, caspase-8, and caspase-3 in the enhanced apoptosis of anaplastic thyroid cancer cells induced by manumycin and paclitaxel. 2001 Oct 3
42 10976921 Plasma membrane estrogen receptors signal to antiapoptosis in breast cancer. 2000 Sep 2