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35414769 | Disruption of peroxisome proliferator-activated receptor α in hepatocytes protects against acetaminophen-induced liver injury by activating the IL-6/STAT3 pathway. | 2022 |
4 |
| 2 |
33395599 | Sleep disorders are associated with acetaminophen-induced adverse reactions and liver injury. | 2021 Feb |
1 |
| 3 |
29730296 | FGF21 mediates the protective effect of fenofibrate against acetaminophen -induced hepatotoxicity via activating autophagy in mice. | 2018 Sep 5 |
2 |
| 4 |
28583670 | Hepatic hypoxia-inducible factors inhibit PPARα expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity. | 2017 Sep |
1 |
| 5 |
26398229 | Loss of 5-lipoxygenase activity protects mice against paracetamol-induced liver toxicity. | 2016 Jan |
1 |
| 6 |
26850476 | Enhanced hepatotoxicity by acetaminophen in Vanin-1 knockout mice is associated with deficient proliferative and immune responses. | 2016 Apr |
4 |
| 7 |
25689681 | Identification of modulators of the nuclear receptor peroxisome proliferator-activated receptor α (PPARα) in a mouse liver gene expression compendium. | 2015 |
1 |
| 8 |
22318764 | Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity. | 2012 Jul |
3 |
| 9 |
19256530 | Serum metabolomics reveals irreversible inhibition of fatty acid beta-oxidation through the suppression of PPARalpha activation as a contributing mechanism of acetaminophen-induced hepatotoxicity. | 2009 Apr |
4 |
| 10 |
18501395 | Nonalcoholic steatohepatitic (NASH) mice are protected from higher hepatotoxicity of acetaminophen upon induction of PPARalpha with clofibrate. | 2008 Aug 1 |
4 |
| 11 |
12958197 | Activation of PPAR-alpha in streptozotocin-induced diabetes is essential for resistance against acetaminophen toxicity. | 2003 Sep |
2 |
| 12 |
11006348 | PPAR-alpha: a key to the mechanism of hepatoprotection by clofibrate. | 2000 Oct |
1 |
| 13 |
11006363 | Peroxisome proliferator-activated receptor alpha-null mice lack resistance to acetaminophen hepatotoxicity following clofibrate exposure. | 2000 Oct |
3 |
| 14 |
10522648 | The PPAR activator docosahexaenoic acid prevents acetaminophen hepatotoxicity in male CD-1 mice. | 1999 Oct 15 |
3 |