| 1 |
34417577 | TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2. | 2022 May |
2 |
| 2 |
35151835 | Glaucocalyxin A impairs tumor growth via amplification of the ATF4/CHOP/CHAC1 cascade in human oral squamous cell carcinoma. | 2022 May 23 |
1 |
| 3 |
33454563 | Melatonin protects against environmental stress-induced fetal growth restriction via suppressing ROS-mediated GCN2/ATF4/BNIP3-dependent mitophagy in placental trophoblasts. | 2021 Apr |
2 |
| 4 |
33946018 | Activation of the eIF2α/ATF4 axis drives triple-negative breast cancer radioresistance by promoting glutathione biosynthesis. | 2021 Jul |
1 |
| 5 |
34553295 | Methionine restriction exposes a targetable redox vulnerability of triple-negative breast cancer cells by inducing thioredoxin reductase. | 2021 Dec |
1 |
| 6 |
34650437 | Nox4 Promotes RANKL-Induced Autophagy and Osteoclastogenesis via Activating ROS/PERK/eIF-2α/ATF4 Pathway. | 2021 |
3 |
| 7 |
32121537 | ATF4-Dependent NRF2 Transcriptional Regulation Promotes Antioxidant Protection during Endoplasmic Reticulum Stress. | 2020 Mar 1 |
1 |
| 8 |
32506763 | ROS-mediated PERK-eIF2α-ATF4 pathway plays an important role in arsenite-induced L-02 cells apoptosis via regulating CHOP-DR5 signaling. | 2020 Oct |
2 |
| 9 |
32885420 | Protective role of HO-1 against acute kidney injury caused by cutaneous exposure to arsenicals. | 2020 Nov |
1 |
| 10 |
30552230 | Combinations of Tyrosine Kinase Inhibitor and ERAD Inhibitor Promote Oxidative Stress-Induced Apoptosis through ATF4 and KLF9 in Medullary Thyroid Cancer. | 2019 Mar |
2 |
| 11 |
30765862 | Mitochondrial GPT2 plays a pivotal role in metabolic adaptation to the perturbation of mitochondrial glutamine metabolism. | 2019 Jun |
1 |
| 12 |
30798142 | Luteolin, a flavonoid, as an anticancer agent: A review. | 2019 Apr |
2 |
| 13 |
31090954 | MicroRNA-214 contributes to regulation of necroptosis via targeting ATF4 in diabetes-associated periodontitis. | 2019 Sep |
1 |
| 14 |
29964331 | Inhibition of euchromatin histone-lysine N-methyltransferase 2 sensitizes breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through reactive oxygen species-mediated activating transcription factor 4-C/EBP homologous protein-death receptor 5 pathway activation. | 2018 Nov |
1 |
| 15 |
30380689 | Activated Integrated Stress Response Induced by Salubrinal Promotes Cisplatin Resistance in Human Gastric Cancer Cells via Enhanced xCT Expression and Glutathione Biosynthesis. | 2018 Oct 29 |
2 |
| 16 |
28254665 | Early-stage autophagy protects nucleus pulposus cells from glucose deprivation-induced degeneration via the p-eIF2α/ATF4 pathway. | 2017 May |
2 |
| 17 |
28457938 | PARP inhibition protects mitochondria and reduces ROS production via PARP-1-ATF4-MKP-1-MAPK retrograde pathway. | 2017 Jul |
2 |
| 18 |
28524233 | Bortezomib sensitizes human osteosarcoma cells to adriamycin-induced apoptosis through ROS-dependent activation of p-eIF2α/ATF4/CHOP axis. | 2017 Sep 1 |
1 |
| 19 |
26661339 | Decursin enhances TRAIL-induced apoptosis through oxidative stress mediated- endoplasmic reticulum stress signalling in non-small cell lung cancers. | 2016 Mar |
2 |
| 20 |
26742780 | Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling. | 2016 Feb 1 |
2 |
| 21 |
27634458 | Endoplasmic reticulum stress-mediated neuronal apoptosis by acrylamide exposure. | 2016 Nov 1 |
1 |
| 22 |
27708226 | Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROS-activated GCN2-eIF2α-ATF4-xCT pathway. | 2016 Nov 8 |
2 |
| 23 |
26176264 | Disruption of the ribosomal P complex leads to stress-induced autophagy. | 2015 |
2 |
| 24 |
24525405 | Valproic acid suppresses Nrf2/Keap1 dependent antioxidant protection through induction of endoplasmic reticulum stress and Keap1 promoter DNA demethylation in human lens epithelial cells. | 2014 Apr |
2 |
| 25 |
24939851 | Role of activating transcription factor 3 (ATF3) in endoplasmic reticulum (ER) stress-induced sensitization of p53-deficient human colon cancer cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through up-regulation of death receptor 5 (DR5) by zerumbone and celecoxib. | 2014 Aug 1 |
2 |
| 26 |
25236743 | Oxidative stress-dependent activation of the eIF2α–ATF4 unfolded protein response branch by skin sensitizer 1-fluoro-2,4-dinitrobenzene modulates dendritic-like cell maturation and inflammatory status in a biphasic manner [corrected]. | 2014 Dec |
1 |
| 27 |
23554101 | The chalcone 2'-hydroxy-4',5'-dimethoxychalcone activates death receptor 5 pathway and leads to apoptosis in human nonsmall cell lung cancer cells. | 2013 Jun |
1 |
| 28 |
21709020 | PERK integrates autophagy and oxidative stress responses to promote survival during extracellular matrix detachment. | 2011 Sep |
1 |
| 29 |
18768473 | Hypoxic reactive oxygen species regulate the integrated stress response and cell survival. | 2008 Nov 7 |
2 |
| 30 |
17707795 | TRB3 protects cells against the growth inhibitory and cytotoxic effect of ATF4. | 2007 Oct 1 |
5 |