Paclitaxel

cyclin B1 ; Homo sapiens







40 Article(s)
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1 34126457 N-acetylgalactosamine-decorated nanoliposomes for targeted delivery of paclitaxel to hepatocellular carcinoma. 2021 Oct 15 3
2 34435645 Proteasome inhibitors decrease paclitaxel‑induced cell death in nasopharyngeal carcinoma with the accumulation of CDK1/cyclin B1. 2021 Oct 3
3 34510641 FASN inhibition sensitizes metastatic OSCC cells to cisplatin and paclitaxel by downregulating cyclin B1. 2021 Sep 12 3
4 32401925 Treatment with β-elemene combined with paclitaxel inhibits growth, migration, and invasion and induces apoptosis of ovarian cancer cells by activation of STAT-NF-κB pathway. 2020 1
5 32494162 MiR-153-5p Enhances the Sensitivity of Triple-Negative Breast Cancer Cells to Paclitaxel by Inducing G2M Phase Arrest. 2020 1
6 30851646 Blocking Mitotic Exit of Ovarian Cancer Cells by Pharmaceutical Inhibition of the Anaphase-Promoting Complex Reduces Chromosomal Instability. 2019 Apr 1
7 31249607 M2I-1 disrupts the in vivo interaction between CDC20 and MAD2 and increases the sensitivities of cancer cell lines to anti-mitotic drugs via MCL-1s. 2019 1
8 31295843 Inhibition of Phosphatidylinositol 3-kinase (PI3K) Signaling Synergistically Potentiates Antitumor Efficacy of Paclitaxel and Overcomes Paclitaxel-Mediated Resistance in Cervical Cancer. 2019 Jul 10 2
9 31906029 Activation of PERK Contributes to Apoptosis and G2/M Arrest by Microtubule Disruptors in Human Colorectal Carcinoma Cells . 2019 Dec 30 1
10 29299936 Development of a novel morphological paclitaxel-loaded PLGA microspheres for effective cancer therapy: in vitro and in vivo evaluations. 2018 Nov 1
11 30008912 β-elemene enhances anticancer bone neoplasms efficacy of paclitaxel through regulation of GPR124 in bone neoplasms cells. 2018 Aug 1
12 30101722 Anticancer Mechanism of Lobaplatin as Monotherapy and in Combination with Paclitaxel in Human Gastric Cancer. 2018 2
13 25708932 C-MYC modulation induces responsiveness to paclitaxel in adrenocortical cancer cell lines. 2015 May 1
14 24695965 Conditional targeting of MAD1 to kinetochores is sufficient to reactivate the spindle assembly checkpoint in metaphase. 2014 Oct 1
15 23114644 Overexpression of cyclin B1 antagonizes chemotherapeutic-induced apoptosis through PTEN/Akt pathway in human esophageal squamous cell carcinoma cells. 2013 Jan 2
16 23628417 Tumor suppressor BLU promotes paclitaxel antitumor activity by inducing apoptosis through the down-regulation of Bcl-2 expression in tumorigenesis. 2013 May 24 1
17 22264882 Hypoxia decreased chemosensitivity of breast cancer cell line MCF-7 to paclitaxel through cyclin B1. 2012 Feb 5
18 22469813 RNA interference targeting CHFR enhances taxol chemosensitivity in endometrial cancer cells. 2012 Jul 1
19 22544540 High expression of TIMP-1 in human breast cancer tissues is a predictive of resistance to paclitaxel-based chemotherapy. 2012 Dec 1
20 23023313 Taxol-induced growth arrest and apoptosis is associated with the upregulation of the Cdk inhibitor, p21WAF1/CIP1, in human breast cancer cells. 2012 Dec 2
21 19609944 Tissue inhibitor of metalloproteinase-1 protects MCF-7 breast cancer cells from paclitaxel-induced apoptosis by decreasing the stability of cyclin B1. 2010 Jan 15 3
22 17960385 The effect of p53 gene expression on the inhibition of cell proliferation by paclitaxel. 2008 Aug 2
23 18813780 Low doses of paclitaxel potently induce apoptosis in human retinoblastoma Y79 cells by up-regulating E2F1. 2008 Oct 1
24 19113992 Targeting cyclin B1 inhibits proliferation and sensitizes breast cancer cells to taxol. 2008 Dec 29 4
25 16278675 Stable gene silencing of cyclin B1 in tumor cells increases susceptibility to taxol and leads to growth arrest in vivo. 2006 Mar 16 1
26 16356831 2-Methoxyestradiol and paclitaxel have similar effects on the cell cycle and induction of apoptosis in prostate cancer cells. 2006 Jan 8 2
27 16528475 Regulation of survivin by retinoic acid and its role in paclitaxel-mediated cytotoxicity in MCF-7 breast cancer cells. 2006 Apr 1
28 16849574 E2F-1 overexpression in U2OS cells increases cyclin B1 levels and cdc2 kinase activity and sensitizes cells to antimitotic agents. 2006 Jul 15 2
29 15688426 Novel indication for cancer therapy: Chk1 inhibition sensitizes tumor cells to antimitotics. 2005 Jul 1 1
30 14695171 Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer. 2003 Dec 15 1
31 26680929 Differential Sensitivity of Taxol-induced Apoptosis in U2OS and SaOS2 Osteogenic Sarcoma Cells. 2003 Apr 1
32 11843726 Analysis of cell-cycle checkpoint pathways in head and neck cancer cell lines: implications for therapeutic strategies. 2002 Feb 1
33 10810342 Induction of senescence-like phenotype and loss of paclitaxel sensitivity after wild-type p53 gene transfection of p53-null human non-small cell lung cancer H358 cells. 2000 Mar-Apr 1
34 11225845 Activation of MAD 2 checkprotein and persistence of cyclin B1/CDC 2 activity associate with paclitaxel-induced apoptosis in human nasopharyngeal carcinoma cells. 2000 Jun 4
35 10347252 Overexpression of p21(waf1) decreases G2-M arrest and apoptosis induced by paclitaxel in human sarcoma cells lacking both p53 and functional Rb protein. 1999 Jun 1
36 9438385 Taxol-induced p34cdc2 kinase activation and apoptosis inhibited by 12-O-tetradecanoylphorbol-13-acetate in human breast MCF-7 carcinoma cells. 1998 Jan 4
37 9506539 Accumulation of cyclin B1, activation of cyclin B1-dependent kinase and induction of programmed cell death in human epidermoid carcinoma KB cells treated with taxol. 1998 Mar 16 6
38 9668078 Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis. 1998 Jul 24 3
39 9721872 Paclitaxel-induced apoptosis is associated with expression and activation of c-Mos gene product in human ovarian carcinoma SKOV3 cells. 1998 Aug 15 2
40 14646529 Cell cycle G2/M arrest and activation of cyclin-dependent kinases associated with low-dose paclitaxel-induced sub-G1 apoptosis. 1997 1