| 1 |
34260721 | Inhibition of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the nicotinamide adenine dinucleotide (NAD) salvage pathway, to target glioma heterogeneity through mitochondrial oxidative stress. | 2022 Feb 1 |
1 |
| 2 |
35012648 | Mesenchymal stromal cells attenuate alveolar type 2 cells senescence through regulating NAMPT-mediated NAD metabolism. | 2022 Jan 10 |
1 |
| 3 |
35060352 | Nampt activator P7C3 ameliorates diabetes and improves skeletal muscle function modulating cell metabolism and lipid mediators. | 2022 Apr |
2 |
| 4 |
35063804 | NAMPT mitigates colitis severity by supporting redox-sensitive activation of phagocytosis in inflammatory macrophages. | 2022 Apr |
8 |
| 5 |
35218657 | Intestinal Epithelial NAD+ Biosynthesis Regulates GLP-1 Production and Postprandial Glucose Metabolism in Mice. | 2022 Apr 1 |
5 |
| 6 |
35228549 | SIRT1 selectively exerts the metabolic protective effects of hepatocyte nicotinamide phosphoribosyltransferase. | 2022 Feb 28 |
3 |
| 7 |
35385807 | Optimization of NAMPT activators to achieve in vivo neuroprotective efficacy. | 2022 Jun 5 |
2 |
| 8 |
35399501 | AZD5153, a Bivalent BRD4 Inhibitor, Suppresses Hepatocarcinogenesis by Altering BRD4 Chromosomal Landscape and Modulating the Transcriptome of HCC Cells. | 2022 |
1 |
| 9 |
35490894 | Crocin ameliorates depressive-like behaviors induced by chronic restraint stress via the NAMPT-NAD+-SIRT1 pathway in mice. | 2022 Jul |
1 |
| 10 |
33049665 | Signaling pathways and effectors of aging. | 2021 Jan 1 |
2 |
| 11 |
33528041 | Mitochondrial translation deficiency impairs NAD+ -mediated lysosomal acidification. | 2021 Apr 15 |
2 |
| 12 |
33543238 | Importance of Adipose Tissue NAD+ Biology in Regulating Metabolic Flexibility. | 2021 Mar 1 |
2 |
| 13 |
33563078 | Metabolomic and transcriptional profiling reveals bioenergetic stress and activation of cell death and inflammatory pathways in vivo after neuronal deletion of NAMPT. | 2021 Aug |
5 |
| 14 |
33788980 | Ablation of Nampt in AgRP neurons leads to neurodegeneration and impairs fasting- and ghrelin-mediated food intake. | 2021 May |
2 |
| 15 |
33810973 | Inhibition of nicotinamide phosphoribosyltransferase protects against acute pancreatitis via modulating macrophage polarization and its related metabolites. | 2021 Aug |
4 |
| 16 |
33818184 | Nicotinamide phosphoribosyltransferase inhibitor ameliorates mouse aging-induced cognitive impairment. | 2021 Oct |
4 |
| 17 |
33928788 | Nampt Potentiates Antioxidant Defense in Diabetic Cardiomyopathy. | 2021 Jun 25 |
5 |
| 18 |
33949241 | Nicotinamide improves NAD+ levels to protect against acetaminophen-induced acute liver injury in mice. | 2021 Nov |
1 |
| 19 |
34119711 | Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity. | 2021 Nov |
5 |
| 20 |
34187548 | Anti-tumor NAMPT inhibitor, KPT-9274, mediates gender-dependent murine anemia and nephrotoxicity by regulating SIRT3-mediated SOD deacetylation. | 2021 Jun 29 |
2 |
| 21 |
34374300 | NAD+ Redox Imbalance in the Heart Exacerbates Diabetic Cardiomyopathy. | 2021 Aug |
2 |
| 22 |
34380043 | NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells. | 2021 Aug 10 |
4 |
| 23 |
34520170 | Butyl Benzyl Phthalate Promotes Adipogenesis in 3T3-L1 Cells via the miRNA-34a-5p Signaling Pathway in the Absence of Exogenous Adipogenic Stimuli. | 2021 Nov 15 |
2 |
| 24 |
34719594 | Discovery of DS68702229 as a Potent, Orally Available NAMPT (Nicotinamide Phosphoribosyltransferase) Activator. | 2021 |
6 |
| 25 |
34752167 | NAMPT-mediated NAD+ biosynthesis suppresses activation of hepatic stellate cells and protects against CCl4-induced liver fibrosis in mice. | 2021 Dec |
2 |
| 26 |
34762911 | Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes. | 2021 Dec |
4 |
| 27 |
31791580 | Intracellular cAMP contents regulate NAMPT expression via induction of C/EBPβ in adipocytes. | 2020 Feb 12 |
2 |
| 28 |
31838391 | 2, 2', 4, 4'-tetrabromodiphenyl ether (BDE-47) induces mitochondrial dysfunction and related liver injury via eliciting miR-34a-5p-mediated mitophagy impairment. | 2020 Mar |
1 |
| 29 |
31873757 | Extracellular signal-regulated kinase 1/2 regulates NAD metabolism during acute kidney injury through microRNA-34a-mediated NAMPT expression. | 2020 Sep |
2 |
| 30 |
31896781 | OT-82, a novel anticancer drug candidate that targets the strong dependence of hematological malignancies on NAD biosynthesis. | 2020 Jul |
2 |
| 31 |
31900990 | Fasting- and ghrelin-induced food intake is regulated by NAMPT in the hypothalamus. | 2020 Apr |
3 |
| 32 |
31974433 | Targeting NAD immunometabolism limits severe graft-versus-host disease and has potent antileukemic activity. | 2020 Jul |
2 |
| 33 |
31988240 | A nicotinamide phosphoribosyltransferase-GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus. | 2020 Mar 13 |
1 |
| 34 |
32049549 | NAD+ precursors protect corneal endothelial cells from UVB-induced apoptosis. | 2020 Apr 1 |
2 |
| 35 |
32278117 | Depot-specific regulation of NAD+/SIRTs metabolism identified in adipose tissue of mice in response to high-fat diet feeding or calorie restriction. | 2020 Jun |
2 |
| 36 |
32389638 | Reversal of endothelial dysfunction by nicotinamide mononucleotide via extracellular conversion to nicotinamide riboside. | 2020 Aug |
1 |
| 37 |
32533606 | Over-expression of Nicotinamide phosphoribosyltransferase in mouse cells confers protective effect against oxidative and ER stress-induced premature senescence. | 2020 Aug |
1 |
| 38 |
32629939 | Nicotinamide Phosphoribosyltransferase (Nampt)/Nicotinamide Adenine Dinucleotide (NAD) Axis Suppresses Atrial Fibrillation by Modulating the Calcium Handling Pathway. | 2020 Jun 30 |
6 |
| 39 |
32636388 | Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry. | 2020 Jul 7 |
4 |
| 40 |
32908120 | Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) with OT-82 induces DNA damage, cell death, and suppression of tumor growth in preclinical models of Ewing sarcoma. | 2020 Sep 10 |
2 |
| 41 |
32998997 | Local Targeting of NAD+ Salvage Pathway Alters the Immune Tumor Microenvironment and Enhances Checkpoint Immunotherapy in Glioblastoma. | 2020 Nov 15 |
3 |
| 42 |
33488923 | NAMPT/SIRT1 Attenuate Ang II-Induced Vascular Remodeling and Vulnerability to Hypertension by Inhibiting the ROS/MAPK Pathway. | 2020 |
10 |
| 43 |
30218374 | NAD metabolism and the SLC34 family: evidence for a liver-kidney axis regulating inorganic phosphate. | 2019 Jan |
1 |
| 44 |
30774990 | Epigenetic regulation of NfatC1 transcription and osteoclastogenesis by nicotinamide phosphoribosyl transferase in the pathogenesis of arthritis. | 2019 |
1 |
| 45 |
30777853 | Nicotinamide Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-Derived Suppressor Cells. | 2019 Apr 15 |
3 |
| 46 |
30833708 | Nicotinamide phosphoribosyltransferase aggravates inflammation and promotes atherosclerosis in ApoE knockout mice. | 2019 Sep |
4 |
| 47 |
31141164 | NAMPT regulates PKM2 nuclear location through 14-3-3ζ: Conferring resistance to tamoxifen in breast cancer. | 2019 Dec |
2 |
| 48 |
31204283 | Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice. | 2019 Aug 6 |
1 |
| 49 |
31320478 | Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity. | 2019 Sep 6 |
5 |
| 50 |
31324777 | Boosting NAD+ with a small molecule that activates NAMPT. | 2019 Jul 19 |
1 |