Cysteine

Parkinsonism associated deglycase ; Homo sapiens







68 Article(s)
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Pub. Year
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1 35303520 Modulation of signaling pathways by DJ-1: An updated overview. 2022 May 1
2 33669258 Impact of DJ-1 and Helix 8 on the Proteome and Degradome of Neuron-Like Cells. 2021 Feb 16 1
3 34515295 Stepwise oxidations play key roles in the structural and functional regulations of DJ-1. 2021 Oct 15 2
4 34680099 DJ-1 Acts as a Scavenger of α-Synuclein Oligomers and Restores Monomeric Glycated α-Synuclein. 2021 Oct 6 1
5 31891690 DJ-1-binding compound B enhances Nrf2 activity through the PI3-kinase-Akt pathway by DJ-1-dependent inactivation of PTEN. 2020 Feb 15 1
6 31377986 Backbone resonance assignment of human DJ-1 in the reduced state and in the cysteine sulfinic acid state. 2019 Oct 2
7 31460051 Polymerization of Oxidized DJ-1 via Noncovalent and Covalent Binding: Significance of Disulfide Bond Formation. 2019 Jun 30 2
8 31474749 The effect of cysteine oxidation on DJ-1 cytoprotective function in human alveolar type II cells. 2019 Sep 2 2
9 28707023 Oxidative inactivation of the endogenous antioxidant protein DJ-1 by the food contaminants 3-MCPD and 2-MCPD. 2018 Jan 2
10 29218631 Intracellular metal binding and redox behavior of human DJ-1. 2018 Jan 1
11 29753659 A conserved human DJ1-subfamily motif (DJSM) is critical for anti-oxidative and deglycase activities of Plasmodium falciparum DJ1. 2018 Jun 2
12 30011180 Chemical Probe To Monitor the Parkinsonism-Associated Protein DJ-1 in Live Cells. 2018 Aug 17 3
13 30190129 A transient post-translational modification of active site cysteine alters binding properties of the parkinsonism protein DJ-1. 2018 Sep 26 2
14 28177569 The oxidized thiol proteome in aging and cataractous mouse and human lens revealed by ICAT labeling. 2017 Apr 2
15 29147904 The Multifaceted Roles of DJ-1 as an Antioxidant. 2017 1
16 29147905 Transcriptional Regulation of DJ-1. 2017 2
17 29147908 DJ-1 as a Biomarker of Parkinson's Disease. 2017 4
18 26945066 Oxidant-induced Interprotein Disulfide Formation in Cardiac Protein DJ-1 Occurs via an Interaction with Peroxiredoxin 2. 2016 May 6 7
19 27105916 DJ-1 activates SIRT1 through its direct binding to SIRT1. 2016 May 20 2
20 27470541 Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson's disease patients. 2016 Jul 29 2
21 27556455 Novel Redox-Dependent Esterase Activity (EC 3.1.1.2) for DJ-1: Implications for Parkinson's Disease. 2016 Aug 22 3
22 25416785 Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residues. 2015 Jan 16 3
23 26048984 Epidermal Growth Factor-dependent Activation of the Extracellular Signal-regulated Kinase Pathway by DJ-1 Protein through Its Direct Binding to c-Raf Protein. 2015 Jul 17 5
24 24397869 Proteomic profiling of nitrosative stress: protein S-oxidation accompanies S-nitrosylation. 2014 Mar 21 2
25 24832775 Use of cysteine-reactive cross-linkers to probe conformational flexibility of human DJ-1 demonstrates that Glu18 mutations are dimers. 2014 Sep 4
26 24894116 Oxidized DJ-1 as a possible biomarker of Parkinson's disease. 2014 May 4
27 24918637 Immunostaining of oxidized DJ-1 in human and mouse brains. 2014 Jul 1
28 25283443 Stereospecific mechanism of DJ-1 glyoxalases inferred from their hemithioacetal-containing crystal structures. 2014 Dec 1
29 23149933 Oxidized DJ-1 inhibits p53 by sequestering p53 from promoters in a DNA-binding affinity-dependent manner. 2013 Jan 4
30 23766857 Neuroprotective function of DJ-1 in Parkinson's disease. 2013 2
31 23847046 DJ-1 associates with lipid rafts by palmitoylation and regulates lipid rafts-dependent endocytosis in astrocytes. 2013 Dec 1 1
32 24144264 Structure of Cu(I)-bound DJ-1 reveals a biscysteinate metal binding site at the homodimer interface: insights into mutational inactivation of DJ-1 in Parkinsonism. 2013 Oct 30 1
33 22104028 Effect of single amino acid substitution on oxidative modifications of the Parkinson's disease-related protein, DJ-1. 2012 Feb 1
34 22431735 Dopamine-derived quinones affect the structure of the redox sensor DJ-1 through modifications at Cys-106 and Cys-53. 2012 May 25 4
35 22515803 Conservation of oxidative protein stabilization in an insect homologue of parkinsonism-associated protein DJ-1. 2012 May 8 2
36 22554508 Stimulation of vesicular monoamine transporter 2 activity by DJ-1 in SH-SY5Y cells. 2012 May 18 3
37 22687481 2'-Benzoyloxycinnamaldehyde-mediated DJ-1 upregulation protects MCF-7 cells from mitochondrial damage. 2012 1
38 20812780 The role of cysteine oxidation in DJ-1 function and dysfunction. 2011 Jul 1 3
39 21160133 DJ-1-Mediated protective effect of protocatechuic aldehyde against oxidative stress in SH-SY5Y cells. 2011 2
40 21670272 Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion. 2011 Jun 28 1
41 21740546 Neuroprotective effect of a new DJ-1-binding compound against neurodegeneration in Parkinson's disease and stroke model rats. 2011 Jul 8 3
42 21893204 Identification of an artificial peptide motif that binds and stabilizes reduced human DJ-1. 2011 Dec 1
43 22132160 Oxidation of DJ-1 induced by 6-hydroxydopamine decreasing intracellular glutathione. 2011 2
44 20304780 Parkinson disease protein DJ-1 converts from a zymogen to a protease by carboxyl-terminal cleavage. 2010 Jun 15 1
45 20630867 Evolution of new enzymatic function by structural modulation of cysteine reactivity in Pseudomonas fluorescens isocyanide hydratase. 2010 Sep 17 3
46 20708070 Elevation of oxidized DJ-1 in the brain and erythrocytes of Parkinson disease model animals. 2010 Oct 15 3
47 18711745 Mitochondrial localization of DJ-1 leads to enhanced neuroprotection. 2009 Jan 2
48 19124468 Formation of a stabilized cysteine sulfinic acid is critical for the mitochondrial function of the parkinsonism protein DJ-1. 2009 Mar 6 2
49 19498271 Kaempferol derivatives prevent oxidative stress-induced cell death in a DJ-1-dependent manner. 2009 Jun 3
50 19703902 Oxidative status of DJ-1-dependent activation of dopamine synthesis through interaction of tyrosine hydroxylase and 4-dihydroxy-L-phenylalanine (L-DOPA) decarboxylase with DJ-1. 2009 Oct 16 3