Fatty Acids

nuclear receptor subfamily 1, group H, member 3 ; Mus musculus







47 Article(s)
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Pub. Year
#Total Relationships
1 35150895 Enterocyte-specific ATGL overexpression affects intestinal and systemic cholesterol homeostasis. 2022 Apr 2
2 33188828 Synthetic high-density lipoproteins delivering liver X receptor agonist prevent atherogenesis by enhancing reverse cholesterol transport. 2021 Jan 10 1
3 35082691 Expressing the Human Cholesteryl Ester Transfer Protein Minigene Improves Diet-Induced Fatty Liver and Insulin Resistance in Female Mice. 2021 1
4 30602604 LXR Alpha Restricts Gammaherpesvirus Reactivation from Latently Infected Peritoneal Cells. 2019 Mar 15 1
5 31421115 Acanthoic acid modulates lipogenesis in nonalcoholic fatty liver disease via FXR/LXRs-dependent manner. 2019 Sep 25 2
6 29632203 Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages. 2018 May 15 1
7 29702089 Oxyresveratrol ameliorates nonalcoholic fatty liver disease by regulating hepatic lipogenesis and fatty acid oxidation through liver kinase B1 and AMP-activated protein kinase. 2018 Jun 1 1
8 28239648 Liver X receptor α mediates hepatic triglyceride accumulation through upregulation of G0/G1 Switch Gene 2 expression. 2017 Feb 23 4
9 26833026 Intestinal Phospholipid Remodeling Is Required for Dietary-Lipid Uptake and Survival on a High-Fat Diet. 2016 Mar 8 1
10 27251289 Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis. 2016 Jun 2 1
11 23945440 Liver X receptor activation increases hepatic fatty acid desaturation by the induction of SCD1 expression through an LXRα-SREBP1c-dependent mechanism. 2014 May 1
12 24688217 Role of Nrf2 in the alteration of cholesterol and bile acid metabolism-related gene expression by dietary cholesterol in high fat-fed mice. 2014 Mar 1
13 24807964 Activation of liver X receptors inhibits hedgehog signaling, clonogenic growth, and self-renewal in multiple myeloma. 2014 Jul 1
14 23609963 Liver X receptors, nervous system, and lipid metabolism. 2013 Jun 2
15 23651738 Resveratrol inhibits LXRα-dependent hepatic lipogenesis through novel antioxidant Sestrin2 gene induction. 2013 Aug 15 2
16 23686114 Differential regulation of gene expression by LXRs in response to macrophage cholesterol loading. 2013 Jul 3
17 22739758 Soy protein isoflavones differentially regulate liver X receptor isoforms to modulate lipid metabolism and cholesterol transport in the liver and intestine in mice. 2012 Sep 1
18 21573029 Metabolic changes in skin caused by Scd1 deficiency: a focus on retinol metabolism. 2011 May 9 1
19 21609322 PPARα-LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status. 2011 Aug 1 1
20 21704188 n-3 fatty acids ameliorate hepatic steatosis and dysfunction after LXR agonist ingestion in mice. 2011 Sep 2
21 21792736 Effect of synthetic ligands of PPAR α, β/δ, γ, RAR, RXR and LXR on the fatty acid composition of phospholipids in mice. 2011 Nov 1
22 19889862 The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction. 2010 Feb 1
23 20218765 Genetic control of de novo lipogenesis: role in diet-induced obesity. 2010 Jun 2
24 19119143 Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha-mediated improvement of hepatic lipid profile. 2009 Mar 6 2
25 19724022 Fetal liver X receptor activation acutely induces lipogenesis but does not affect plasma lipid response to a high-fat diet in adult mice. 2009 Nov 1
26 20067898 LXR regulate cholesterol homeostasis in the proximal mouse epididymis. 2009 1
27 18356535 A cholesterol-free, high-fat diet suppresses gene expression of cholesterol transporters in murine small intestine. 2008 May 2
28 18840761 Pharmacological activation of LXR in utero directly influences ABC transporter expression and function in mice but does not affect adult cholesterol metabolism. 2008 Dec 2
29 17088263 Cholesterol feeding strongly reduces hepatic VLDL-triglyceride production in mice lacking the liver X receptor alpha. 2007 Feb 2
30 17341595 Multiple roles of the nuclear receptors for oxysterols liver X receptor to maintain male fertility. 2007 May 1
31 16325781 Different roles of liver X receptor alpha and beta in lipid metabolism: effects of an alpha-selective and a dual agonist in mice deficient in each subtype. 2006 Feb 14 1
32 16368743 Liver X receptor agonist TO-901317 upregulates SCD1 expression in renal proximal straight tubule. 2006 May 1
33 16876124 Improved metabolic control by depletion of Liver X Receptors in mice. 2006 Sep 15 1
34 15855229 Differential regulation of fatty acid elongation enzymes in brown adipocytes implies a unique role for Elovl3 during increased fatty acid oxidation. 2005 Oct 2
35 15913974 LXR is crucial in lipid metabolism. 2005 Jul 2
36 16123164 Hepatic peroxisomal fatty acid beta-oxidation is regulated by liver X receptor alpha. 2005 Dec 1
37 14967823 LXR-mediated activation of macrophage stearoyl-CoA desaturase generates unsaturated fatty acids that destabilize ABCA1. 2004 May 2
38 12554745 On the role of liver X receptors in lipid accumulation in adipocytes. 2003 Feb 2
39 12730332 Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling. 2003 Jul 6
40 12897148 Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression. 2003 Aug 1
41 12923232 The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse. 2003 Nov 1
42 11781314 Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis. 2002 Mar 22 1
43 12032330 Synthetic LXR ligand inhibits the development of atherosclerosis in mice. 2002 May 28 1
44 12097330 Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles. 2002 Sep 13 3
45 12196343 Accumulation of foam cells in liver X receptor-deficient mice. 2002 Aug 27 1
46 12449021 LXRs; oxysterol-activated nuclear receptors that regulate genes controlling lipid homeostasis. 2002 Apr 1
47 11090131 Role of LXRs in control of lipogenesis. 2000 Nov 15 1