Bile Acids and Salts

cytochrome P450 family 7 subfamily A member 1 ; Rattus norvegicus







180 Article(s)
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Pub. Year
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1 35283218 Discovery of farnesoid X receptor and its role in bile acid metabolism. 2022 May 15 1
2 33766756 Effects of Danhong injection on dyslipidemia and cholesterol metabolism in high-fat diets fed rats. 2021 Jun 28 1
3 34064649 Kinsenoside Alleviates 17α-Ethinylestradiol-Induced Cholestatic Liver Injury in Rats by Inhibiting Inflammatory Responses and Regulating FXR-Mediated Bile Acid Homeostasis. 2021 May 11 1
4 34899293 Untargeted and Targeted Metabolomics Reveal the Underlying Mechanism of Aspirin Eugenol Ester Ameliorating Rat Hyperlipidemia via Inhibiting FXR to Induce CYP7A1. 2021 2
5 32173762 Dominant gut Prevotella copri in gastrectomised non-obese diabetic Goto-Kakizaki rats improves glucose homeostasis through enhanced FXR signalling. 2020 Jun 1
6 32240813 Integrative proteomics-metabolomics strategy reveals the mechanism of hepatotoxicity induced by Fructus Psoraleae. 2020 Jun 15 1
7 32414094 Dietary Betaine Addition Promotes Hepatic Cholesterol Synthesis, Bile Acid Conversion, and Export in Rats. 2020 May 13 1
8 32422221 FGF15 improves outcomes after brain dead donor liver transplantation with steatotic and non-steatotic grafts in rats. 2020 Nov 1
9 32926925 Palmatine regulates bile acid cycle metabolism and maintains intestinal flora balance to maintain stable intestinal barrier. 2020 Dec 1 1
10 30453824 Uteroplacental Insufficiency Impairs Cholesterol Elimination in Adult Female Growth-Restricted Rat Offspring Fed a High-Fat Diet. 2019 Sep 3
11 30956864 Effects of sanshoamides and capsaicinoids on plasma and liver lipid metabolism in hyperlipidemic rats. 2019 Apr 2
12 30985903 Experimental Evidence of Liver Injury by BSEP-Inhibiting Drugs With a Bile Salt Supplementation in Rats. 2019 Jul 1 1
13 29198707 Impaired vagus function in rats suppresses bile acid synthesis in the liver by disrupting tight junctions and activating Fxr-Fgf15 signaling in the intestine. 2018 Jan 1 1
14 29438852 Transcriptome analysis to assess the cholestatic hepatotoxicity induced by Polygoni Multiflori Radix: Up-regulation of key enzymes of cholesterol and bile acid biosynthesis. 2018 Apr 15 2
15 29896121 Prenatal Exposure to a Maternal High Fat Diet Increases Hepatic Cholesterol Accumulation in Intrauterine Growth Restricted Rats in Part Through MicroRNA-122 Inhibition of Cyp7a1. 2018 3
16 30383974 Bile acid malabsorption is associated with diarrhea in acute phase of colitis. 2018 Dec 1
17 27988401 Geniposide attenuates ANIT-induced cholestasis through regulation of transporters and enzymes involved in bile acids homeostasis in rats. 2017 Jan 20 1
18 28029505 Parenteral nutrition dysregulates bile salt homeostasis in a rat model of parenteral nutrition-associated liver disease. 2017 Oct 1
19 28251657 Hypolipidaemic effect and mechanism of paprika seed oil on Sprague-Dawley rats. 2017 Sep 1
20 28888833 Iron depletion induces hepatic secretion of biliary lipids and glutathione in rats. 2017 Dec 3
21 29147129 The effect of exercise training on upregulation of molecular markers of bile acid metabolism in the liver of ovariectomized rats fed a cholesterol-rich diet. 2017 Jul 1
22 26710098 Taurine ameliorates cholesterol metabolism by stimulating bile acid production in high-cholesterol-fed rats. 2016 Mar 2
23 26923514 Quercetin regulates hepatic cholesterol metabolism by promoting cholesterol-to-bile acid conversion and cholesterol efflux in rats. 2016 Mar 1
24 27133208 Glucocorticoid treatment alters systemic bile acid homeostasis by regulating the biosynthesis and transport of bile salts. 2016 Jul 2
25 27255380 Pyrazinamide Induced Rat Cholestatic Liver Injury through Inhibition of FXR Regulatory Effect on Bile Acid Synthesis and Transport. 2016 Aug 1
26 25634785 Bile acid promotes liver regeneration via farnesoid X receptor signaling pathways in rats. 2015 Jun 1
27 25683903 Alpinumisoflavone and abyssinone V 4'-methylether derived from Erythrina lysistemon (Fabaceae) promote HDL-cholesterol synthesis and prevent cholesterol gallstone formation in ovariectomized rats. 2015 Jul 1
28 25710810 Effect of the particle size of cellulose from sweet potato residues on lipid metabolism and cecal conditions in ovariectomized rats. 2015 Apr 1
29 25912874 Influence of dietary sugar on cholesterol and bile acid metabolism in the rat: Marked reduction of hepatic Abcg5/8 expression following sucrose ingestion. 2015 Jun 12 1
30 26424014 Dioxin-Produced Alteration in the Profiles of Fecal and Urinary Metabolomes: A Change in Bile Acids and Its Relevance to Toxicity. 2015 1
31 24197062 Effect of chronic renal failure on the hepatic, intestinal, and renal expression of bile acid transporters. 2014 Jan 1 1
32 24212381 Protein restoration in low-birth-weight rat offspring derived from maternal low-protein diet leads to elevated hepatic CYP3A and CYP2C11 activity in adulthood. 2014 Feb 1
33 25066374 A GAPDH-mediated trans-nitrosylation pathway is required for feedback inhibition of bile salt synthesis in rat liver. 2014 Nov 4
34 25119340 Combination of intrauterine growth restriction and a high-fat diet impairs cholesterol elimination in rats. 2014 Nov 1
35 22918684 Dipeptidyl peptidase 4-deficient rats have improved bile secretory function in high fat diet-induced steatosis. 2013 Jan 1
36 23463147 The hypocholesterolemic effect of capsaicinoids in ovariectomized rats fed with a cholesterol-free diet was mediated by inhibition of hepatic cholesterol synthesis. 2013 Apr 30 1
37 23471827 Hypocholesterolemic effect of capsaicinoids by increased bile acids excretion in ovariectomized rats. 2013 Jun 2
38 23852734 FGF15/19 protein levels in the portal blood do not reflect changes in the ileal FGF15/19 or hepatic CYP7A1 mRNA levels. 2013 Oct 1
39 24010021 Hepatic bile acids and bile acid-related gene expression in pregnant and lactating rats. 2013 1
40 22554715 Hypocholesterolemia of Rhizoma Coptidis alkaloids is related to the bile acid by up-regulated CYP7A1 in hyperlipidemic rats. 2012 Jun 15 3
41 22883218 Effects of bile duct ligation and cholic acid treatment on fatty liver in two rat models of non-alcoholic fatty liver disease. 2012 Dec 1
42 23050430 [Active constituents in compound whole grain and its regulation on bile acids metabolism]. 2012 May 2
43 23231860 Hypolipidemic effects of lactic acid bacteria fermented cereal in rats. 2012 Dec 11 1
44 29243638 Cholesterol-lowering effect of dietary Lupinus angustifolius proteins in adult rats through regulation of genes involved in cholesterol homeostasis. 2012 Jun 1 1
45 21291544 Differential gene expression in liver and small intestine from lactating rats compared to age-matched virgin controls detects increased mRNA of cholesterol biosynthetic genes. 2011 Feb 3 1
46 21372147 Maternal protein restriction elevates cholesterol in adult rat offspring due to repressive changes in histone modifications at the cholesterol 7alpha-hydroxylase promoter. 2011 May 2
47 21396994 A new TCM formula FTZ lowers serum cholesterol by regulating HMG-CoA reductase and CYP7A1 in hyperlipidemic rats. 2011 May 17 1
48 21817852 Insulin-dependent suppression of cholesterol 7α-hydroxylase is a possible link between glucose and cholesterol metabolisms. 2011 Oct 31 3
49 22007308 Mechanism of resistance to dietary cholesterol. 2011 1
50 20607063 Hypocholesterolemic effects of curcumin via up-regulation of cholesterol 7a-hydroxylase in rats fed a high fat diet. 2010 Jun 1