Proline

cyclin dependent kinase 5 ; Homo sapiens







47 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34814918 Three decades of Cdk5. 2021 Nov 23 1
2 32286796 Physiological and Pathological Roles of Cdk5: Potential Directions for Therapeutic Targeting in Neurodegenerative Disease. 2020 May 6 2
3 28877958 Proline-dependent and basophilic kinases phosphorylate human TRPC6 at serine 14 to control channel activity through increased membrane expression. 2018 Jan 2
4 29111393 Cyclin-dependent kinase 5-mediated phosphorylation of CHIP promotes the tAIF-dependent death pathway in rotenone-treated cortical neurons. 2018 Jan 1 2
5 29288339 Cdk5 Contributes to Huntington's Disease Learning and Memory Deficits via Modulation of Brain Region-Specific Substrates. 2018 Aug 1
6 26206088 Phosphorylation of CHIP at Ser20 by Cdk5 promotes tAIF-mediated neuronal death. 2016 Feb 2
7 26601962 Neuroprotective Mechanisms Mediated by CDK5 Inhibition. 2016 2
8 27345869 N-terminal tetrapeptide T/SPLH motifs contribute to multimodal activation of human TRPA1 channel. 2016 Jun 27 1
9 25128817 The Cdk5 activator P39 specifically links muskelin to myosin II and regulates stress fiber formation and actin organization in lens. 2015 Jan 1 2
10 25807947 Cdk5: a key player at neuronal synapse with diverse functions. 2015 1
11 26555036 Phosphorylation of a splice variant of collapsin response mediator protein 2 in the nucleus of tumour cells links cyclin dependent kinase-5 to oncogenesis. 2015 Nov 10 1
12 24498195 ERK MAP kinase activation in spinal cord regulates phosphorylation of Cdk5 at serine 159 and contributes to peripheral inflammation induced pain/hypersensitivity. 2014 1
13 25329792 p35 regulates the CRM1-dependent nucleocytoplasmic shuttling of nuclear hormone receptor coregulator-interacting factor 1 (NIF-1). 2014 2
14 23362255 Isomerase Pin1 stimulates dephosphorylation of tau protein at cyclin-dependent kinase (Cdk5)-dependent Alzheimer phosphorylation sites. 2013 Mar 15 2
15 24085300 Structural basis for the different stability and activity between the Cdk5 complexes with p35 and p39 activators. 2013 Nov 8 1
16 24121667 CDK5 is essential for TGF-β1-induced epithelial-mesenchymal transition and breast cancer progression. 2013 Oct 14 1
17 24235147 Cyclin-dependent kinase 5 (Cdk5) regulates the function of CLOCK protein by direct phosphorylation. 2013 Dec 27 2
18 24391960 Cdk5 phosphorylates dopamine D2 receptor and attenuates downstream signaling. 2013 2
19 21924349 Going out of the brain: non-nervous system physiological and pathological functions of Cdk5. 2012 Jan 2
20 22795893 Extraneuronal activities and regulatory mechanisms of the atypical cyclin-dependent kinase Cdk5. 2012 Oct 15 2
21 28066692 Special Issue on "Cdk5 and Brain Disorders": Prologue. 2012 1
22 21056617 Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease. 2011 Jan 1
23 21144757 Design, synthesis, and testing of an 6-O-linked series of benzimidazole based inhibitors of CDK5/p25. 2011 Jan 1 2
24 21145377 The role of Cdk5 in cognition and neuropsychiatric and neurological pathology. 2011 Apr 25 2
25 20061803 Cdk5, the multifunctional surveyor. 2010 Jan 15 1
26 20717630 [Roles of cyclin-dependent kinase 5 in central nervous system development and neurodegenerative diseases]. 2010 Aug 25 2
27 21044075 Regulation and role of cyclin-dependent kinase activity in neuronal survival and death. 2010 Dec 1
28 19343042 Single-nucleotide polymorphisms in the promoter of the CDK5 gene and lung cancer risk in a Korean population. 2009 May 2
29 19457112 Phosphorylation of the homer-binding domain of group I metabotropic glutamate receptors by cyclin-dependent kinase 5. 2009 Jul 2
30 18183483 An unusual member of the Cdk family: Cdk5. 2008 May 1
31 18388733 Che-1 enhances cyclin-dependent kinase 5 expression and interacts with the active kinase-complex. 2008 Mar 26 2
32 18490454 Cooperative roles of c-Abl and Cdk5 in regulation of p53 in response to oxidative stress. 2008 Jul 11 2
33 17394551 Cdk5--p39 is a labile complex with the similar substrate specificity to Cdk5--p35. 2007 Sep 2
34 17526057 The roles of cyclin-dependent kinase 5 in dendrite and synapse development. 2007 Aug 2
35 17591690 Stabilization and activation of p53 induced by Cdk5 contributes to neuronal cell death. 2007 Jul 1 2
36 18076569 Regulation of the interaction of Disabled-1 with CIN85 by phosphorylation with Cyclin-dependent kinase 5. 2007 Dec 2
37 16407116 Cyclin-dependent kinase 5 activity regulates pain signaling. 2006 Jan 17 2
38 16029324 CDK5 regulates cell-cell and cell-matrix adhesion in human keratinocytes. 2005 Jul 1
39 15023357 Neuronal cyclin-dependent kinase 5: role in nervous system function and its specific inhibition by the Cdk5 inhibitory peptide. 2004 Mar 11 1
40 15123626 Cyclin-dependent kinase 5 associated with p39 promotes Munc18-1 phosphorylation and Ca(2+)-dependent exocytosis. 2004 Jul 9 2
41 15342635 Protein kinase CK2 is an inhibitor of the neuronal Cdk5 kinase. 2004 Nov 5 1
42 11248668 The protein kinase Cdk5. Structural aspects, roles in neurogenesis and involvement in Alzheimer's pathology. 2001 Mar 1
43 10386957 CDK-5-mediated neurofilament phosphorylation in SHSY5Y human neuroblastoma cells. 1999 Jul 1
44 10413323 Elevated neuronal Cdc2-like kinase activity in the Alzheimer disease brain. 1999 May 1
45 9378721 Role of the pyrrolidine ring of proline in determining the substrate specificity of cdc2 kinase or cdk5. 1997 Aug 5
46 8702879 Site-specific phosphorylation of synapsin I by mitogen-activated protein kinase and Cdk5 and its effects on physiological functions. 1996 Aug 30 1
47 7566345 Tau domains, phosphorylation, and interactions with microtubules. 1995 May-Jun 1