Acetylcholine

cholinergic receptor nicotinic alpha 4 subunit ; Homo sapiens







160 Article(s)
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1 34756924 Evidence of a dual mechanism of action underlying the anti-proliferative and cytotoxic effects of ammonium-alkyloxy-stilbene-based α7- and α9-nicotinic ligands on glioblastoma cells. 2022 Jan 1
2 35054856 Disorders of the Cholinergic System in COVID-19 Era-A Review of the Latest Research. 2022 Jan 8 1
3 35177988 α-Conotoxin TxIB Improved Behavioral Abnormality and Changed Gene Expression in Zebrafish (Danio rerio) Induced by Alcohol Withdrawal. 2022 1
4 35222535 Comparative Assessment of Outcomes in Drug Treatment for Smoking Cessation and Role of Genetic Polymorphisms of Human Nicotinic Acetylcholine Receptor Subunits. 2022 1
5 35225139 The α9α10 nicotinic acetylcholine receptor: a compelling drug target for hearing loss? 2022 Mar 2
6 32935187 (+)-[18F]Flubatine as a novel α4β2 nicotinic acetylcholine receptor PET ligand-results of the first-in-human brain imaging application in patients with β-amyloid PET-confirmed Alzheimer's disease and healthy controls. 2021 Mar 1
7 33284031 Nicotine: A Targeted Therapy for Epilepsy Due to nAChR Gene Variants. 2021 Apr 1
8 33380469 α3* Nicotinic Acetylcholine Receptors in the Habenula-Interpeduncular Nucleus Circuit Regulate Nicotine Intake. 2021 Feb 24 1
9 33506493 A conserved arginine with non-conserved function is a key determinant of agonist selectivity in α7 nicotinic ACh receptors. 2021 Apr 2
10 33613194 Loss of Choline Agonism in the Inner Ear Hair Cell Nicotinic Acetylcholine Receptor Linked to the α10 Subunit. 2021 1
11 33809417 Garcinol Attenuates Lipoprotein(a)-Induced Oxidative Stress and Inflammatory Cytokine Production in Ventricular Cardiomyocyte through α7-Nicotinic Acetylcholine Receptor-Mediated Inhibition of the p38 MAPK and NF-κB Signaling Pathways. 2021 Mar 16 1
12 33836585 Acetylcholine ameliorates colitis by promoting IL-10 secretion of monocytic myeloid-derived suppressor cells through the nAChR/ERK pathway. 2021 Mar 16 2
13 34197807 Regulation of epithelial sodium channel activity by SARS-CoV-1 and SARS-CoV-2 proteins. 2021 Jul 20 1
14 34301823 Therapeutic Targeting of α7 Nicotinic Acetylcholine Receptors. 2021 Jul 1
15 34471351 Efficient Anti-Glioma Therapy Through the Brain-Targeted RVG15-Modified Liposomes Loading Paclitaxel-Cholesterol Complex. 2021 1
16 31614011 Role of the cutaneous extraneuronal cholinergic system in the pathogenesis of psoriasis: a case-control study. 2020 Jun 1
17 31789411 Cholinergic α5 nicotinic receptor is involved in the proliferation and invasion of human prostate cancer cells. 2020 Jan 2
18 32007796 Roles of nAChR and Wnt signaling in intestinal stem cell function and inflammation. 2020 Apr 1
19 32017982 3-Quinuclidinyl-α-methoxydiphenylacetate: A multi-targeted ligand with antimuscarinic and antinicotinic effects designed for the treatment of anticholinesterase poisoning. 2020 Jun 1 1
20 32031532 Two mutations in the nicotinic acetylcholine receptor subunit A4 (CHRNA4) in a family with autosomal dominant sleep-related hypermotor epilepsy. 2020 Feb 1 1
21 32048843 Menthol Binding to the Human α4β2 Nicotinic Acetylcholine Receptor Facilitated by Its Strong Partitioning in the Membrane. 2020 Mar 12 1
22 32272701 αO-Conotoxin GeXIVA Inhibits the Growth of Breast Cancer Cells via Interaction with α9 Nicotine Acetylcholine Receptors. 2020 Apr 7 1
23 32463026 A Novel Vaccine Employing Non-Replicating Rabies Virus Expressing Chimeric SARS-CoV-2 Spike Protein Domains: Functional Inhibition of Viral/Nicotinic Acetylcholine Receptor Complexes. 2020 May 28 1
24 32577853 The α7 and β2 nicotinic acetylcholine receptor subunits regulate apoptosis in the infant hippocampus, and in sudden infant death syndrome (SIDS). 2020 Aug 1
25 32590127 Swertiamarin, a secoiridoid glycoside modulates nAChR and AChE activity. 2020 Sep 1
26 32649832 Rational Design of α-Conotoxin RegIIA Analogues Selectively Inhibiting the Human α3β2 Nicotinic Acetylcholine Receptor through Computational Scanning. 2020 Sep 16 1
27 32707263 The role of nicotinic acetylcholine receptors in alcohol-related behaviors. 2020 Oct 1
28 32806654 α-Conotoxin as Potential to α7-nAChR Recombinant Expressed in Escherichia coli. 2020 Aug 12 2
29 32957649 Low-Dose Nicotine Activates EGFR Signaling via α5-nAChR and Promotes Lung Adenocarcinoma Progression. 2020 Sep 17 1
30 33074244 Functional α6β4 acetylcholine receptor expression enables pharmacological testing of nicotinic agonists with analgesic properties. 2020 Nov 2 1
31 33184264 Vagus nerve stimulation optimized cardiomyocyte phenotype, sarcomere organization and energy metabolism in infarcted heart through FoxO3A-VEGF signaling. 2020 Nov 12 1
32 33253222 Component of nicotine-induced intracellular calcium elevation mediated through α3- and α5-containing nicotinic acetylcholine receptors are regulated by cyclic AMP in SH-SY 5Y cells. 2020 1
33 30623678 Design, stability and efficacy of a new targeting peptide for nanoparticulate drug delivery to SH-SY5Y neuroblastoma cells. 2019 Nov 1
34 30665006 The α3 and α4 nicotinic acetylcholine receptor (nAChR) subunits in the brainstem medulla of sudden infant death syndrome (SIDS). 2019 May 1
35 30914244 Electrochemical studies of human nAChR a7 subunit phosphorylation by kinases PKA, PKC and Src. 2019 Jun 1 1
36 31175218 Heteromeric Neuronal Nicotinic Acetylcholine Receptors with Mutant β Subunits Acquire Sensitivity to α7-Selective Positive Allosteric Modulators. 2019 Aug 1
37 31242717 A Novel Immunomodulatory Mechanism Dependent on Acetylcholine Secreted by Human Bone Marrow-derived Mesenchymal Stem Cells. 2019 Jul 31 1
38 31421156 Nicotinic acetylcholine receptor at vertebrate motor endplates: Endocytosis, recycling, and degradation. 2019 Oct 15 1
39 31581202 Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury. 2019 1
40 28600847 The fifth subunit of the (α4β2)2 β2 nicotinic ACh receptor modulates maximal ACh responses. 2018 Jun 1
41 28762314 Insights Into Nicotinic Receptor Signaling in Nicotine Addiction: Implications for Prevention and Treatment. 2018 1
42 30072754 Effect of imidacloprid ingestion on immune responses to porcine reproductive and respiratory syndrome virus. 2018 Aug 2 1
43 30362667 Synthesis of a Series of Non-Symmetric Bispyridinium and Related Compounds and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor. 2018 Dec 20 2
44 30687021 Minimal Circuit Model of Reward Prediction Error Computations and Effects of Nicotinic Modulations. 2018 1
45 27573666 Role of the α7 Nicotinic Acetylcholine Receptor and RIC-3 in the Cholinergic Anti-inflammatory Pathway. 2017 1
46 27581650 The potential use of rabies virus glycoprotein-derived peptides to facilitate drug delivery into the central nervous system: a mini review. 2017 Jun 1
47 27871840 Probing the structure of the uncoupled nicotinic acetylcholine receptor. 2017 Feb 1
48 27917874 Discovery, synthesis, biological evaluation and structure-based optimization of novel piperidine derivatives as acetylcholine-binding protein ligands. 2017 Jan 3
49 28221788 Substituted 2-Aminopyrimidines Selective for α7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins. 2017 Mar 15 2
50 28450546 Nicotinic α4β2 Cholinergic Receptor Influences on Dorsolateral Prefrontal Cortical Neuronal Firing during a Working Memory Task. 2017 May 24 2