gemcitabine

hypoxia inducible factor 1 subunit alpha ; Homo sapiens







21 Article(s)
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1 33045974 Studying the Anti-Tumor Effects of siRNA Gene Silencing of Some Metabolic Genes in Pancreatic Ductal Adenocarcinoma. 2021 Oct 25 2
2 33830713 VHH212 nanobody targeting the hypoxia-inducible factor 1α suppresses angiogenesis and potentiates gemcitabine therapy in pancreatic cancer in vivo. 2021 Apr 8 2
3 34593522 LncRNA HIF1A-AS1 Promotes Gemcitabine Resistance of Pancreatic Cancer by Enhancing Glycolysis through Modulating the AKT/YB1/HIF1α Pathway. 2021 Nov 15 4
4 32226541 IL-37/ STAT3/ HIF-1α negative feedback signaling drives gemcitabine resistance in pancreatic cancer. 2020 2
5 32819602 In vitro affinity maturation to improve the efficacy of a hypoxia-inducible factor 1α single-domain intrabody. 2020 Sep 3 1
6 33052979 Quercetin potentializes the respective cytotoxic activity of gemcitabine or doxorubicin on 3D culture of AsPC-1 or HepG2 cells, through the inhibition of HIF-1α and MDR1. 2020 1
7 30628067 Rg3 inhibits gemcitabine-induced lung cancer cell invasiveness through ROS-dependent, NF-κB- and HIF-1α-mediated downregulation of PTX3. 2019 Jul 1
8 31565190 Correction: Inhibition of HIF-1α by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma. 2019 Sep 17 1
9 29693166 Hypoxia-induced autophagy promotes gemcitabine resistance in human bladder cancer cells through hypoxia-inducible factor 1α activation. 2018 Jul 3
10 29772221 miR-301a plays a pivotal role in hypoxia-induced gemcitabine resistance in pancreatic cancer. 2018 Aug 1 1
11 29953500 Potential role of HIF-1-responsive microRNA210/HIF3 axis on gemcitabine resistance in cholangiocarcinoma cells. 2018 1
12 26785721 Hypoxia regulates ABCG2 activity through the activivation of ERK1/2/HIF-1α and contributes to chemoresistance in pancreatic cancer cells. 2016 1
13 25678112 Co-delivery of HIF1α siRNA and gemcitabine via biocompatible lipid-polymer hybrid nanoparticles for effective treatment of pancreatic cancer. 2015 Apr 2
14 24535079 Effects of the HIF-1α and NF-κB loop on epithelial-mesenchymal transition and chemoresistance induced by hypoxia in pancreatic cancer cells. 2014 Apr 1
15 24575976 Gemcitabine resistance is associated with epithelial-mesenchymal transition and induction of HIF-1α in pancreatic cancer cells. 2014 6
16 23579097 BLU enhances the effects of anti-angiogenic activity in combination with gemcitabine-based chemotherapeutic agents. 2013 Jul 1
17 23740244 An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor κB- and hypoxia-inducible factor 1α-mediated up-regulation of CXCR4. 2013 Jul 19 5
18 21839751 CCK-2/gastrin receptor signaling pathway is significant for gemcitabine-induced gene expression of VEGF in pancreatic carcinoma cells. 2011 Oct 24 2
19 21922147 Hypoxia-inducible factor-1α expression and gemcitabine chemotherapy for pancreatic cancer. 2011 Dec 2
20 22993609 Gemcitabine and paclitaxel suppress the production of vascular endothelial growth factor induced by deferoxamine in human non-small cell lung cancer A549 cells. 2010 Sep 2
21 15845181 Clinical significance of hypoxia-inducible factor-1a messenger RNA expression in locally advanced non-small-cell lung cancer after platinum agent and gemcitabine chemotherapy followed by surgery. 2005 Mar 3