| 1 |
34969360 | Induction of lncRNA NORAD accounts for hypoxia-induced chemoresistance and vasculogenic mimicry in colorectal cancer by sponging the miR-495-3p/ hypoxia-inducible factor-1α (HIF-1α). | 2022 Jan |
1 |
| 2 |
34998404 | ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer. | 2022 Jan 8 |
10 |
| 3 |
35355718 | HIF1α/VEGF Feedback Loop Contributes to 5-Fluorouracil Resistance. | 2022 |
5 |
| 4 |
35484214 | HIF-1α stimulates the progression of oesophageal squamous cell carcinoma by activating the Wnt/β-catenin signalling pathway. | 2022 Apr 28 |
2 |
| 5 |
33641785 | Jiedu Sangen decoction inhibits chemoresistance to 5-fluorouracil of colorectal cancer cells by suppressing glycolysis via PI3K/AKT/HIF-1α signaling pathway. | 2021 Feb |
3 |
| 6 |
34540836 | Lack of MOF Decreases Susceptibility to Hypoxia and Promotes Multidrug Resistance in Hepatocellular Carcinoma via HIF-1α. | 2021 |
1 |
| 7 |
32388677 | Activated HIF1α of tumor cells promotes chemoresistance development via recruiting GDF15-producing tumor-associated macrophages in gastric cancer. | 2020 Oct |
5 |
| 8 |
32425596 | Circular RNA circNRIP1 Sponges microRNA-138-5p to Maintain Hypoxia-Induced Resistance to 5-Fluorouracil Through HIF-1α-Dependent Glucose Metabolism in Gastric Carcinoma. | 2020 |
2 |
| 9 |
28454454 | Chemotherapy regimen based on sorafenib combined with 5-FU on HIF-1α and VEGF expression and survival in advanced gastric cancer patients. | 2017 Apr |
1 |
| 10 |
26728163 | Baseline [(18)F]FMISO μPET as a Predictive Biomarker for Response to HIF-1α Inhibition Combined with 5-FU Chemotherapy in a Human Colorectal Cancer Xenograft Model. | 2016 Aug |
3 |
| 11 |
26931435 | Enhancement of Drug Sensitivity by Knockdown of HIF-1α in Gastric Carcinoma Cells. | 2016 |
1 |
| 12 |
27060169 | Adult hematopoietic stem cells lacking Hif-1α self-renew normally. | 2016 Jun 9 |
1 |
| 13 |
27210058 | Metformin in combination with 5-fluorouracil suppresses tumor growth by inhibiting the Warburg effect in human oral squamous cell carcinoma. | 2016 Jul |
1 |
| 14 |
27234614 | l-carnosine dipeptide overcomes acquired resistance to 5-fluorouracil in HT29 human colon cancer cells via downregulation of HIF1-alpha and induction of apoptosis. | 2016 Aug |
3 |
| 15 |
24342832 | Dichloroacetate attenuates hypoxia-induced resistance to 5-fluorouracil in gastric cancer through the regulation of glucose metabolism. | 2014 Feb 15 |
1 |
| 16 |
24788596 | Metformin inhibits proliferation and enhances chemosensitivity of intrahepatic cholangiocarcinoma cell lines. | 2014 Jun |
1 |
| 17 |
25426963 | Advancements in the development of HIF-1α-activated protein switches for use in enzyme prodrug therapy. | 2014 |
2 |
| 18 |
25699390 | Effects of hypoxia-inducible factor-1α silencing on drug resistance of human pancreatic cancer cell line Patu8988/5-Fu. | 2014 Nov-Dec |
1 |
| 19 |
20020496 | HIF-1alpha is an unfavorable determinant of relapse in gastric cancer patients who underwent curative surgery followed by adjuvant 5-FU chemotherapy. | 2010 Sep 1 |
2 |
| 20 |
19171477 | Effect of HIF-1 modulation on the response of two- and three-dimensional cultures of human colon cancer cells to 5-fluorouracil. | 2009 Mar |
2 |
| 21 |
19724845 | Hypoxia-inducible factor-1alpha expression predicts the response to 5-fluorouracil-based adjuvant chemotherapy in advanced gastric cancer. | 2009 Oct |
3 |
| 22 |
17066447 | The involvement of hypoxia-inducible factor-1alpha in the susceptibility to gamma-rays and chemotherapeutic drugs of oral squamous cell carcinoma cells. | 2007 Jan 15 |
1 |
| 23 |
17219956 | Hypoxia-inducible factor-1alpha suppressing apoptosis and increasing tolerance of lung cancer cells to chemotherapy. | 2006 |
2 |
| 24 |
16471319 | Involvement of hypoxia-inducible factor-1-alpha in multidrug resistance induced by hypoxia in HepG2 cells. | 2005 Dec |
2 |