Acetylcysteine

hypoxia inducible factor 1 subunit alpha ; Homo sapiens







38 Article(s)
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1 35629355 The Antileukemic and Anti-Prostatic Effect of Aeroplysinin-1 Is Mediated through ROS-Induced Apoptosis via NOX Activation and Inhibition of HIF-1a Activity. 2022 May 5 2
2 33761438 Spleen tyrosine kinase regulates crosstalk of hypoxia-inducible factor-1α and nuclear factor (erythroid-derived2)-like 2 for B cell survival. 2021 Jun 2
3 33771976 CXCR4 promotes B cell viability by the cooperation of nuclear factor (erythroid-derived 2)-like 2 and hypoxia-inducible factor-1α under hypoxic conditions. 2021 Mar 26 1
4 33806765 Role of the ROS-JNK Signaling Pathway in Hypoxia-Induced Atrial Fibrotic Responses in HL-1 Cardiomyocytes. 2021 Mar 23 1
5 34175667 Ubiquitination and receptor-mediated mitophagy converge to eliminate oxidation-damaged mitochondria during hypoxia. 2021 Sep 2
6 34258270 N-Acetylcysteine Improves Inflammatory Response in COPD Patients by Regulating Th17/Treg Balance through Hypoxia Inducible Factor-1α Pathway. 2021 2
7 35186974 HIF-1α Alleviates High-Glucose-Induced Renal Tubular Cell Injury by Promoting Parkin/PINK1-Mediated Mitophagy. 2021 2
8 32566089 Melatonin Antagonizes Nickel-Induced Aerobic Glycolysis by Blocking ROS-Mediated HIF-1α/miR210/ISCU Axis Activation. 2020 2
9 31310363 Glutathione peroxidase 3 (GPX3) suppresses the growth of melanoma cells through reactive oxygen species (ROS)-dependent stabilization of hypoxia-inducible factor 1-α and 2-α. 2019 Nov 3
10 31885794 Hypoxia-Induced ROS Contribute to Myoblast Pyroptosis during Obstructive Sleep Apnea via the NF-κB/HIF-1α Signaling Pathway. 2019 1
11 29435131 PD-L1 confers resistance to EGFR mutation-independent tyrosine kinase inhibitors in non-small cell lung cancer via upregulation of YAP1 expression. 2018 Jan 12 1
12 29972798 Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling. 2018 Jul 3 1
13 28365254 Regulation of hypoxia-inducible factor-1α in human buccal mucosal fibroblasts stimulated with arecoline. 2017 Jun 1
14 28901751 Sulfate Aerosols Promote Lung Cancer Metastasis by Epigenetically Regulating the Epithelial-to-Mesenchymal Transition (EMT). 2017 Oct 3 4
15 27405163 [Sodium nitrite enhanced the potentials of migration and invasion of human hepatocellular carcinoma SMMC-7721 cells through induction of mitophagy]. 2016 Jan 1
16 27803454 Isorhamnetin Inhibits Reactive Oxygen Species-Dependent Hypoxia Inducible Factor (HIF)-1α Accumulation. 2016 1
17 25406100 Titanium nanoparticle inhalation induces renal fibrosis in mice via an oxidative stress upregulated transforming growth factor-β pathway. 2015 Mar 16 1
18 26088922 Antioxidant inhibition of steady-state reactive oxygen species and cell growth in neuroblastoma. 2015 Sep 1
19 24296245 Hypoxia-inducible factor 1 contributes to N-acetylcysteine's protection in stroke. 2014 Mar 8
20 25272228 TCDD induces the hypoxia-inducible factor (HIF)-1α regulatory pathway in human trophoblastic JAR cells. 2014 Sep 30 1
21 22833345 Attenuation of reactive oxygen species by antioxidants suppresses hypoxia-induced epithelial-mesenchymal transition and metastasis of pancreatic cancer cells. 2013 Feb 1
22 23792775 Role of direct reactivity with metals in chemoprotection by N-acetylcysteine against chromium(VI), cadmium(II), and cobalt(II). 2013 Dec 1
23 25206699 Hypoxia regulates reactive oxygen species levels in SHG-44 glioma cells. 2013 Feb 25 2
24 22648416 Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation. 2012 Jul 20 1
25 21252047 Mammalian target of rapamycin mediates the angiogenic effects of leptin in human hepatic stellate cells. 2011 Aug 1
26 21283817 Chronic CSE treatment induces the growth of normal oral keratinocytes via PDK2 upregulation, increased glycolysis and HIF1α stabilization. 2011 Jan 19 1
27 21595915 Regulation of hypoxia inducible factor-1α expression by the alteration of redox status in HepG2 cells. 2011 May 19 2
28 21980400 PI3K and ERK-induced Rac1 activation mediates hypoxia-induced HIF-1α expression in MCF-7 breast cancer cells. 2011 1
29 20637781 Actin-sequestering protein, thymosin beta-4, induces paclitaxel resistance through ROS/HIF-1alpha stabilization in HeLa human cervical tumor cells. 2010 Aug 28 2
30 20846156 Hypoxia inducible factor-1α expression in areca quid chewing-associated oral squamous cell carcinomas. 2010 Oct 2
31 18199003 LPS induces hypoxia-inducible factor 1 activation in macrophage-differentiated cells in a reactive oxygen species-dependent manner. 2008 May 1
32 17561100 HIF-1alpha activation by a redox-sensitive pathway mediates cyanide-induced BNIP3 upregulation and mitochondrial-dependent cell death. 2007 Jul 1 1
33 17785204 HIF-dependent antitumorigenic effect of antioxidants in vivo. 2007 Sep 1
34 16424008 Nitric oxide is a factor in the stabilization of hypoxia-inducible factor-1alpha in cancer: role of free radical formation. 2006 Jan 15 1
35 12560087 HIF-1 alpha protein as a target for S-nitrosation. 2003 Jan 30 3
36 11886167 Stabilization of hypoxia-inducible factor-1alpha is involved in the hypoxic stimuli-induced expression of vascular endothelial growth factor in osteoblastic cells. 2002 Jan 7 2
37 10801793 Antioxidant/pro-oxidant equilibrium regulates HIF-1alpha and NF-kappa B redox sensitivity. Evidence for inhibition by glutathione oxidation in alveolar epithelial cells. 2000 Jul 14 1
38 11112413 iNOS expression inhibits hypoxia-inducible factor-1 activity. 2000 Dec 9 1