LY3009120

B-Raf proto-oncogene, serine/threonine kinase ; Homo sapiens







9 Article(s)
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1 31645440 A Phase I Study of LY3009120, a Pan-RAF Inhibitor, in Patients with Advanced or Metastatic Cancer. 2020 Feb 3
2 32366411 Antitumor Effects of Pan-RAF Inhibitor LY3009120 Against Lung Cancer Cells Harboring Oncogenic BRAF Mutation. 2020 May 3
3 29059158 RAF inhibitor LY3009120 sensitizes RAS or BRAF mutant cancer to CDK4/6 inhibition by abemaciclib via superior inhibition of phospho-RB and suppression of cyclin D1. 2018 Feb 8 3
4 30118796 Targeting oncogenic Raf protein-serine/threonine kinases in human cancers. 2018 Sep 1
5 27999210 LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer. 2017 Feb 7 1
6 28382170 Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer. 2017 1
7 28576749 A combinatorial strategy using YAP and pan-RAF inhibitors for treating KRAS-mutant pancreatic cancer. 2017 Aug 28 1
8 26732095 Oncogenic BRAF Deletions That Function as Homodimers and Are Sensitive to Inhibition by RAF Dimer Inhibitor LY3009120. 2016 Mar 8
9 26343583 Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers. 2015 Sep 14 6