tanespimycin

B-Raf proto-oncogene, serine/threonine kinase ; Homo sapiens







5 Article(s)
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1 18281615 17-AAG and 17-DMAG-induced inhibition of cell proliferation through B-Raf downregulation in WT B-Raf-expressing uveal melanoma cell lines. 2008 Jun 4
2 18375819 BRAF and NRAS mutations in melanoma: potential relationships to clinical response to HSP90 inhibitors. 2008 Apr 1
3 18676857 Oxidative stress plays a critical role in inactivating mutant BRAF by geldanamycin derivatives. 2008 Aug 1 1
4 16371460 V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors. 2006 Jan 3 1
5 16322212 Activated B-RAF is an Hsp90 client protein that is targeted by the anticancer drug 17-allylamino-17-demethoxygeldanamycin. 2005 Dec 1 1