| 1 |
32767959 | Docking Studies and Antiproliferative Activities of 6-(3-aryl-2-propenoyl)-2(3H)- benzoxazolone Derivatives as Novel Inhibitors of Phosphatidylinositol 3-Kinase (PI3Kα). | 2021 |
1 |
| 2 |
31816384 | Insight into the mechanism of allosteric activation of PI3Kα by oncoprotein K-Ras4B. | 2020 Feb 1 |
2 |
| 3 |
33139939 | Phosphatidylinositol-3-OH kinase signalling is spatially organized at endosomal compartments by microtubule-associated protein 4. | 2020 Nov |
1 |
| 4 |
30747208 | Expression and significance of EBV, ARID1A and PIK3CA in gastric carcinoma. | 2019 Mar |
1 |
| 5 |
30952761 | Exon 9 Mutation of PIK3CA Associated With Poor Survival in Patients With Epstein-Barr Virus-associated Gastric Cancer. | 2019 Apr |
1 |
| 6 |
31135801 | The structural basis for Ras activation of PI3Kα lipid kinase. | 2019 Jun 5 |
2 |
| 7 |
31525283 | Nicotinic acid affects cytoskeleton remodeling via increasing the activity of gelsolin. | 2019 Jul |
2 |
| 8 |
31790629 | PI3Kα in cardioprotection: Cytoskeleton, late Na+ current, and mechanism of arrhythmias. | 2019 Dec |
2 |
| 9 |
31802830 | Reduced microRNA 375 in colorectal cancer upregulates metadherin-mediated signaling. | 2019 Nov 28 |
1 |
| 10 |
29484141 | Association between PIK3CA alteration and prognosis of gastric cancer patients: a meta-analysis. | 2018 Jan 26 |
1 |
| 11 |
29549527 | In vitro efficacy of ARQ 092, an allosteric AKT inhibitor, on primary fibroblast cells derived from patients with PIK3CA-related overgrowth spectrum (PROS). | 2018 May |
2 |
| 12 |
29636989 | Comprehensive molecular screening by next generation sequencing reveals a distinctive mutational profile of KIT/PDGFRA genes and novel genomic alterations: results from a 20-year cohort of patients with GIST from north-western Greece. | 2018 |
1 |
| 13 |
29985963 | PIK3CA mutations are specifically localized to lymphatic endothelial cells of lymphatic malformations. | 2018 |
1 |
| 14 |
29211993 | Single-Molecule Study Reveals How Receptor and Ras Synergistically Activate PI3Kα and PIP3 Signaling. | 2017 Dec 5 |
1 |
| 15 |
26921096 | Mutation distributions and clinical correlations of PIK3CA gene mutations in breast cancer. | 2016 Jun |
1 |
| 16 |
28060271 | Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures. | 2016 Dec 26 |
1 |
| 17 |
26053643 | Molecular spectrum of PIK3CA gene mutations in patients with nonsmall-cell lung cancer in Turkey. | 2015 Jul |
1 |
| 18 |
26627007 | Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations. | 2015 Dec 15 |
1 |
| 19 |
25043846 | Engineering of an isolated p110α subunit of PI3Kα permits crystallization and provides a platform for structure-based drug design. | 2014 Oct |
1 |
| 20 |
25103565 | PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors. | 2014 Aug 8 |
1 |
| 21 |
25105564 | Structural basis of nSH2 regulation and lipid binding in PI3Kα. | 2014 Jul 30 |
1 |
| 22 |
25309634 | Activation of PI3Kα by physiological effectors and by oncogenic mutations: structural and dynamic effects. | 2014 Mar 1 |
4 |
| 23 |
25422220 | Detection of PIK3CA gene mutations with HRM analysis and association with IGFBP-5 expression levels in breast cancer. | 2014 |
1 |
| 24 |
19509113 | Blocking phosphoinositide 3-kinase activity in colorectal cancer cells reduces proliferation but does not increase apoptosis alone or in combination with cytotoxic drugs. | 2009 Jun |
1 |
| 25 |
15135396 | Cloning, expression, purification, and characterization of the human Class Ia phosphoinositide 3-kinase isoforms. | 2004 Jun |
1 |
| 26 |
10947948 | Comparison of the kinetic properties of the lipid- and protein-kinase activities of the p110alpha and p110beta catalytic subunits of class-Ia phosphoinositide 3-kinases. | 2000 Sep 1 |
1 |
| 27 |
7929193 | Biochemical characterization of the free catalytic p110 alpha and the complexed heterodimeric p110 alpha.p85 alpha forms of the mammalian phosphatidylinositol 3-kinase. | 1994 Oct 7 |
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