Serine

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ; Homo sapiens







18 Article(s)
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Title
Pub. Year
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1 34907409 Hierarchical microgroove/nanopore topography regulated cell adhesion to enhance osseointegration around intraosseous implants in vivo. 2022 Jan 18 1
2 35125881 An Analysis of the Pathogenic Genes and Mutation Sites of Macrodactyly. 2022 1
3 35201653 miR-186-5p inhibits the progression of oral squamous cell carcinoma by targeting ITGA6 to impair the activity of the PI3K/AKT pathway. 2022 Apr 1
4 35402577 Circulating exosomal miR-21 mediates HUVEC proliferation and migration through PTEN/PI3K/AKT in Crohn's disease. 2022 Mar 1
5 33488873 Prognostic value of the PIK3CA, AKT, and PTEN mutations in oral squamous cell carcinoma: literature review. 2021 1
6 32120136 Targeting AKT/PKB to improve treatment outcomes for solid tumors. 2020 Jan - Apr 1
7 31056260 Osthole promotes the suppressive effects of cisplatin on NRF2 expression to prevent drug-resistant cervical cancer progression. 2019 Jun 25 1
8 27393705 Dual Inhibition of PI3K/Akt and mTOR by the Dietary Antioxidant, Delphinidin, Ameliorates Psoriatic Features In Vitro and in an Imiquimod-Induced Psoriasis-Like Disease in Mice. 2017 Jan 10 1
9 27401370 p53 Loses grip on PIK3CA expression leading to enhanced cell survival during platinum resistance. 2016 Oct 1
10 22502592 Definition of the binding mode of a new class of phosphoinositide 3-kinase α-selective inhibitors using in vitro mutagenesis of non-conserved amino acids and kinetic analysis. 2012 Jun 15 1
11 23270540 Autophosphorylation of serine 608 in the p85 regulatory subunit of wild type or cancer-associated mutants of phosphoinositide 3-kinase does not affect its lipid kinase activity. 2012 Dec 27 2
12 19638206 PIK3CA alterations in Middle Eastern ovarian cancers. 2009 Jul 28 1
13 19815551 Non-redundant roles of phosphoinositide 3-kinase isoforms alpha and beta in glycoprotein VI-induced platelet signaling and thrombus formation. 2009 Dec 4 2
14 18829572 PIK3CA cooperates with other phosphatidylinositol 3'-kinase pathway mutations to effect oncogenic transformation. 2008 Oct 1 1
15 16815847 Peroxisome proliferator-activated receptor gamma promotes epithelial to mesenchymal transformation by Rho GTPase-dependent activation of ERK1/2. 2006 Aug 25 2
16 16009713 Interferon induces NF-kappa B-inducing kinase/tumor necrosis factor receptor-associated factor-dependent NF-kappa B activation to promote cell survival. 2005 Sep 9 1
17 10488146 JAK1-dependent phosphorylation of insulin receptor substrate-1 (IRS-1) is inhibited by IRS-1 serine phosphorylation. 1999 Sep 24 1
18 9446654 The p85 and p110 subunits of phosphatidylinositol 3-kinase-alpha are substrates, in vitro, for a constitutively associated protein tyrosine kinase in platelets. 1998 Feb 1 2